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ASTRAZENECA PLC

AZNCF
$290.60B
Mega Cap
NASDAQBiotechnology🇺🇸North America94.3K employees

Drugs in Pipeline

303

Phase 3 Programs

188

Upcoming Catalysts

16

Next Catalyst

This month

Market Overview

Stock performance and key metrics

AZNCF News
Catalyst Timeline

16 upcoming, 4 past

Phase 2Next

Zibotentan/Dapagliflozin Phase 2 Est. Readout

July 2026~STALE+IMMINENTZibotentan/Dapagliflozin224

Estimated primary completion for Zibotentan/Dapagliflozin trial (NCT06942910) in Chronic Kidney Disease With High Proteinuria. Topline data typically follows completion by weeks to months.

Source

15 more catalysts beyond 14 days

Start a 48-hour free trial to see all upcoming catalysts

Pro
Drug Pipeline

candsartan cilexetil

Phase 3

Pediatric Hypertension

Simvastatin

Phase 3

Hypercholesterolemia

Etoposide

Phase 3

Non-small Cell Lung Cancer

Baxdrostat/dapagliflozin

Phase 3

Chronic Kidney Disease and Hypertension

Pemetrexed

Phase 3

NSCLC

Glyburide

Phase 3

Diabetes

Quetiapine fumarate (Seroquel) SR

Phase 3

Affective Psychosis, Bipolar

Seloken ZOK/Toprol-XL

Phase 3

Heart Failure, Congestive

Quetiapine Fumarate (SEROQUEL) Extended Release

Phase 3

Bipolar Depression

Risperidone

Phase 3

Schizophrenia

Budesonide/formoterol (SYMBICORT) pMDI

Phase 3

Asthma

Esomeprazole 40 mg

Phase 3

Gastric Ulcer

Symbicort, used twice daily (b.i.d) and as needed (prn)

Phase 3

Asthma

AZD0120

Phase 3

Relapsed Refractory Multiple Myeloma

Camizestrant

Phase 3

Breast Cancer, Early Breast Cancer

budesonide

Phase 3

Asthma

Tamoxifen

Phase 3

Bone Density

Paclitaxel

Phase 3

Metastatic Breast Cancer

Candesartan

Phase 3

Congestive Heart Failure

Puxitatug Samrotecan

Phase 3

Endometrial Cancer

Ticagrelor

Phase 3

Peripheral Artery Disease

Symbicort pMDI

Phase 3

Asthma

Rosuvastatin calcium

Phase 3

Coronary Arteriosclerosis

pramlintide acetate

Phase 3

Overweight

BDA MDI HFO 160/180 μg

Phase 3

Asthma

Rilvegostomig

Phase 3

Biliary Tract Cancer

Symbicort

Phase 3

Asthma

Domvanalimab

Phase 3

Non-Small Cell Lung Cancer

75mg selumetinib

Phase 3

Metastatic

glimepiride

Phase 3

Type 2 Diabetes Mellitus

biphasic insulin aspart

Phase 3

Diabetes Mellitus, Type 2

AZD9833

Phase 3

Advanced ER-Positive HER2-Negative Breast Cancer

Letrozole

Phase 3

ER-Positive HER2-Negative Breast Cancer

Ranitidine

Phase 3

NSAID Associated Gastric Ulcers

Tralokinumab

Phase 3

Asthma

Budesonide/formoterol Turbuhaler

Phase 3

Asthma

candesartan cilexetil

Phase 3

Type 1 Diabetes

dacarbazine

Phase 3

Melanoma

AZD9291 80 mg/40 mg

Phase 3

Stage IB-IIIA Non-small Cell Lung Carcinoma

AZD0780

Phase 3

Cardiovascular Disease

Anastrozole (Arimidex)

Phase 3

Breast Cancer

savolitinib

Phase 3

Carcinoma

MEDI4736 (Durvalumab)

Phase 3

Advanced Solid Malignancies

Sunitinib

Phase 3

Carcinoma

sitagliptin

Phase 3

Type 2 Diabetes

Carboplatin

Phase 3

Endometrial Cancer

Tozorakimab

Phase 3

Asthma

Metformin XR

Phase 3

Type 2 Diabetes

AZD0486

Phase 3

B-cell Acute Lymphoblastic Leukemia (B-ALL)

methotrexate

Phase 3

Squamous Cell Carcinoma of the Head and Neck

Rosuvastatin 20mg

Phase 3

Homozygous Familial Hypercholesterolemia (HoFH)

Aclidinium bromide

Phase 3

Chronic Obstructive Pulmonary Disease

Aclidinium Bromide/Formoterol Fumarate

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Duloxetine

Phase 3

Major Depressive Disorder

Olaparib 300mg tablets

Phase 3

Newly Diagnosed

MEDI4736 (Durvalumab)+Tremelimumab

Phase 3

Non-Small-Cell Lung Carcinoma NSCLC

Exemestane

Phase 3

Locally Advanced Breast Cancer

Symbicort Turbuhaler (Budesonide/formoterol)

Phase 3

Chronic Obstructive Pulmonary Disease

rosiglitazone

Phase 3

Diabetes Mellitus, Type 2

AZD0585

Phase 3

Hypertriglyceridemia

Gefitinib or Docetaxel

Phase 3

Non-Small Cell Lung Cancer

Surovatamig

Phase 3

Untreated Follicular Lymphoma

insulin glargine

Phase 3

Type 2 Diabetes Mellitus

R-mini-CHOP

Phase 3

Large B-cell Lymphoma

Budesonide/formoterol pMDI 40/2.25ug + spacer

Phase 3

Asthma

MEDI4736

Phase 3

Ovarian

Glycopyrronium/Formoterol Fumarate

Phase 3

Chronic Obstructive Pulmonary Disease COPD

D961H sachet 10 mg

Phase 3

Gastric Ulcer (GU)

Budesonide/formoterol pMDI

Phase 3

Chronic Obstructive Pulmonary Disease

Eribulin

Phase 3

Breast Cancer

Volrustomig

Phase 3

Unresectable Pleural Mesothelioma

Docetaxel

Phase 3

Non-Small-Cell Lung Carcinoma

MEDI8897

Phase 3

Respiratory Syncytial Virus Infections

AZD9291

Phase 3

Non-Small Cell Lung Cancer

BFF MDI 160/9.6 μg BID (320/19.2μg/day)

Phase 3

Asthma

Ribociclib

Phase 3

ER-Positive HER2-Negative Breast Cancer

Formoterol Turbuhaler

Phase 3

Chronic Obstructive Pulmonary Disease

Durvalumab + Chemotherapy phase

Phase 3

Advanced or Recurrent Endometrial Cancer

Anastozole (Arimidex)

Phase 3

Breast Cancer

pioglitazone

Phase 3

Type 2 Diabetes Mellitus

Prednisolone

Phase 3

Chronic Obstructive Pulmonary Disease

liraglutide

Phase 3

Type 2 Diabetes Mellitus

AZD9291 Dosing

Phase 3

Lung Cancer

insulin detemir

Phase 3

Type 2 Diabetes Mellitus

Experimental: Tralokinumab

Phase 3

Uncontrolled Asthma

Nab-paclitaxel

Phase 3

Non-small Cell Lung Cancer

Durvalumab (MEDI4736)

Phase 3

Non Small Cell Lung Carcinoma NSCLC

BGF MDI 320/14.4/9.6 μg

Phase 3

COPD (Chronic Obstructive Pulmonary Disease)

Salbutamol

Phase 3

COPD

Dato-DXd

Phase 3

Metastatic Non-small Cell Lung Cancer

TC-5214

Phase 3

Major Depressive Disorder

Fluticasone propionate

Phase 3

Seasonal Allergic Rhinitis

Vinblastine

Phase 3

Urinary Bladder Neoplasms

Open Label Run In Esomeprazole

Phase 3

Gastroesophageal Reflux Disease (GERD)

exenatide twice daily

Phase 3

Type 2 Diabetes Mellitus

NXY-059

Phase 3

Cerebral Stroke

Metoprolol Succinate

Phase 3

High Blood Pressure (Hypertension).

Fulvestrant

Phase 3

Advanced Breast Cancer

Exenatide once weekly suspension

Phase 3

Diabetes Type 2

Elecoglipron

Phase 3

Type 2 Diabetes Mellitus

Ciclesonide Nasal Spray

Phase 3

Rhinitis, Allergic, Seasonal

Tezepelumab

Phase 3

Asthma

Nirsevimab

Phase 3

Lower Respiratory Tract Infection

Experimental: Tezepelumab

Phase 3

Asthma

formoterol

Phase 3

Stable Asthma

Quetiapine Extended Release

Phase 3

Schizophrenia

Tremelimumab

Phase 3

Non Small Cell Lung Cancer NSCLC

enzalutamide

Phase 3

Metastatic Castration-resistant Prostate Cancer

Dapagliflozin 10 mg

Phase 3

Type 2 Diabetes Mellitus

Monalizumab

Phase 3

Squamous Cell Carcinoma of the Head and Neck

Ticagrelor 90 mg

Phase 3

Myocardial Infarction

Aclidinium bromide/formoterol Fixed-Dose Combination

Phase 3

COPD

Gemcitabine

Phase 3

Urothelial Cancer

Foscarnet sodium

Phase 3

HIV Infections

Pravastatin

Phase 3

Hypercholesterolemia

Quetiapine SR

Phase 3

Anxiety Disorders

Biological: Experimental: Tezepelumab

Phase 3

Severe Asthma

Paroxetine

Phase 3

Generalized Anxiety Disorder

AZD2265

Phase 3

Metastatic Castration-resistant Prostate Cancer

MEDI3250

Phase 3

Healthy Japanese Children Age 2 Years Through 6 Years

abiraterone acetate

Phase 3

Metastatic Castration-resistant Prostate Cancer

Capivasertib

Phase 3

Triple Negative Breast Neoplasms

Metformin IR

Phase 3

Diabetes Mellitus, Type 2

Formoterol (OT)

Phase 3

Chronic Obstructive Pulmonary Disease

fostamatinib

Phase 3

Rheumatoid Arthritis

fluticasone

Phase 3

Asthma

Aclidinium bromide/formoterol Fixed-Dose Combination (FDC)

Phase 3

Chronic Obstructive Pulmonary Disease

Anastrozole

Phase 3

Breast Neoplasms

Roflumilast

Phase 3

Asthma

metformin

Phase 3

Type 2 Diabetes Mellitus

SEROQUEL (quetiapine fumarate) Tablets

Phase 3

Bipolar Disorder

Taxane

Phase 3

Breast Cancer; HER2-positive; Metastatic

Rosuvastatin

Phase 3

Aortic Stenosis

Esomeprazole

Phase 3

NSAIDs

Osimertinib

Phase 3

Non-Small Cell Lung Cancer

Formoterol Fumarate

Phase 3

Chronic Obstructive Pulmonary Disease

Exenatide Once Weekly

Phase 3

Type 2 Diabetes Mellitus

Cisplatin

Phase 3

Non-Small Cell Lung Cancer

olaparib

Phase 3

Colorectal Cancer

Dapagliflozin

Phase 3

Type 2 Diabetes Mellitus

Ciclesonide

Phase 3

Asthma

Saxagliptin

Phase 3

Type 2 Diabetes

Quetiapine

Phase 3

Psychotic Disorders

AC2993

Phase 3

Diabetes Mellitus, Non-Insulin-Dependent

Bicalutamide

Phase 3

Prostate Cancer

budesonide/formoterol

Phase 3

Asthma

Quetiapine fumarate

Phase 3

Schizophrenia

Budesonide Turbuhaler (Pulmicort)

Phase 3

Asthma

Saruparib

Phase 3

Metastatic Castration-Sensitive Prostate Cancer

Symbicort Turbuhaler

Phase 3

Asthma

Quetiapine XR

Phase 3

Schizophrenic Disorders

Erlotinib 150/100 mg

Phase 3

Locally Advanced or Metastatic EGFR Sensitising Mutation Positive Non Small Cell Lung Cancer

AZD0901

Phase 3

Gastric Cancer

Ramucirumab+ paclitaxel

Phase 3

Gastric Cancer

Budesonide/formoterol (Symbicort Turbuhaler)

Phase 3

Chronic Obstructive Pulmonary Disease

Selumetinib

Phase 3

Neurofibromatosis 1

AZD7442

Phase 3

COVID-19

Ropivacaine

Phase 3

Anesthesia,Spinal

Chlorambucil

Phase 3

Untreated Chronic Lymphocytic Leukemia

Acalabrutinib

Phase 3

Phase I: Relapsed or Refractory B-cell Malignancies

ARIMIDEX (anastrazole)

Phase 3

Breast Cancer

Terbutaline

Phase 3

Asthma

budesonide (Pulmicort)

Phase 3

Chronic Obstructive Pulmonary Disease

Sodium Zirconium Cyclosilicate (ZS) 5g

Phase 3

Hyperkalemia

HFA MDI

Phase 3

Asthma

Ceralasertib

Phase 3

Advanced or Metastatic NSCLC

Esomeprazole (Nexium)

Phase 3

Gastroesophageal Reflux Disease (GERD)

Durvalumab +Tremelimumab

Phase 3

Non Small Cell Lung Carcinoma NSCLC

Durvalumab

Phase 3

Hepatocellular Carcinoma

Gefitinib

Phase 3

NSCLC

Atorvastatin

Phase 3

Hypercholesterolaemia

Baxdrostat

Phase 3

Primary Hyperaldosteronism

Benralizumab 30 mg SC + Mometasone Furoate

Phase 3

Nasal Polyposis

Sodium Zirconium Cyclosilicate 5g

Phase 3

Hyperkalemia

Datopotamab Deruxtecan

Phase 3

Non-Small Cell Lung Cancer

Capecitabine

Phase 3

Breast Cancer

budesonide/formoterol (Symbicort)

Phase 3

Mild or Moderate Asthma

Seroquel SR

Phase 3

Schizophrenia

NKTR-118

Phase 3

Opioid-Induced Constipation (OIC)

fluticasone/salmeterol

Phase 3

Asthma

Benralizumab

Phase 3

Asthma

Omeprazole

Phase 3

Non-erosive Reflux Disease

Terbutaline Turbuhaler

Phase 3

Asthma

exenatide

Phase 3

Type 2 Diabetes Mellitus

Anifrolumab

Phase 3

Active Systemic Lupus Erythematosus

Lithium

Phase 3

Mania

BGF MDI 320/28.8/9.6 μg

Phase 3

Asthma

Lenvatinib

Phase 3

Hepatocellular Carcinoma

MEDI4736 + Tremelimumab

Phase 2

Recurrent/Metastatic Squamous Cell Carcinoma of Head & Neck

gefitinib (IRESSA™, ZD1839)

Phase 2

Breast Cancer

AZD2811

Phase 2

Small-Cell Lung Cancer

Omega-3 carboxylic acids

Phase 2

T2 Diabetes and Fatty Liver Disease (Non-alcoholic Origin)

Durvalumab / Tremelimumab Combination Therapy

Phase 2

Pediatric Cancer

Vinorelbine

Phase 2

Non-Small-Cell Lung Carcinoma

AZD1419

Phase 2

Asthma

AZD6765 iv

Phase 2

Major Depressive Disorder

Tomudex

Phase 2

Inoperable or Recurrent Rectal Cancer

AZD1656

Phase 2

Type II Diabetes

Arimidex 1 mg

Phase 2

McCune-Albright Syndrome

AZD0837

Phase 2

Persistent or Permanent Non-valvular Atrial Fibrillation

Goserelin acetate

Phase 2

Breast Cancer

AZD1222

Phase 2

COVID-19

AZD6793

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

AZD8359

Phase 2

Metastatic Prostate Cancer

AZD7798

Phase 2

Moderate to Severe Crohn's Disease

AZD9567

Phase 2

Rheumatoid Arthritis

AZD0865

Phase 2

GERD With Erosive Esophagitis

AZD9750

Phase 2

Prostate Cancer

AZD1305

Phase 2

Left Ventricle Function

AZD3355

Phase 2

Reflux Episodes

AZD7268

Phase 2

Major Depressive Disorder

Quetiapine fumarate (Seroquel)

Phase 2

Major Depressive Disorder

AZD9668

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

AZD5305

Phase 2

Metastatic Prostate Cancer

AZD1236

Phase 2

Chronic Obstructive Pulmonary Disease

5-FU

Phase 2

Sub-study 1 Cervical Cancer (Volrustomig Monotherapy)

AZD7624 1.0 mg

Phase 2

Chronic Obstructive Pulmonary Disease COPD

AZD3480

Phase 2

Alzheimer Disease

LAS100977

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

Tesaglitazar

Phase 2

Type 2 Diabetes

ZD4054

Phase 2

Non Small Cell Lung Cancer

AZD0292

Phase 2

Bronchiectasis With Pseudomonas Aeruginosa Colonization

AZD6765

Phase 2

Depression

Aclidinium bromide and formoterol

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

Cediranib

Phase 2

Renal Cell Carcinoma

clopidogrel

Phase 2

Stable Coronary Artery Disease

Gefitinib 250mg

Phase 2

Lung Cancer

AZD4831

Phase 2

Non-Cirrhotic Non-alcoholic Steatohepatitis With Fibrosis

MEDI0382 100 μg

Phase 2

Type 2 Diabetes

Selumetinib granule formulation

Phase 2

Neurofibromatosis Type 1

MEDI-546

Phase 2

Systemic Lupus Erythematosus

AZD3199

Phase 2

Asthma

AZD2423

Phase 2

Chronic Obstructive Pulmonary Disease

AZD2516, 5 mg

Phase 2

Reflux

AZD2265 (FPI-2265)

Phase 2

Metastatic Prostate Cancer

MEDI3506

Phase 2

Diabetic Kidney Disease

AZD9550

Phase 2

Obesity or Overweight

AZD4547

Phase 2

FGFR Inhibition, Pharmacokinetics, Biomarkers

AZD4635

Phase 2

Progressive Metastatic Castrate-Resistant Prostate Cancer

CP-675,206 (Tremelimumab)

Phase 2

Colorectal Neoplasms

AZD5423

Phase 2

Asthma

Selumetinib+Docetaxel

Phase 2

Locally Advanced or Metastatic Non-Small-Cell Lung Cancer (Stage IIIB-IV)

AZD2066

Phase 2

Pain

AZD4604

Phase 2

Asthma

AZD5004

Phase 2

Obesity or Overweight

CP-675,206

Phase 2

Carcinoma, Non-small-cell Lung

AZD4573

Phase 2

Relapsed/Refractory Peripheral T-cell Lymphoma

AZD2171

Phase 2

Gastrointestinal Stromal Tumors

Zibotentan/Dapagliflozin

Phase 2

Chronic Kidney Disease With High Proteinuria

Febuxostat

Phase 2

Asymptomatic Hyperuricemia

AZD1386

Phase 2

Pain

AZD2389

Phase 2

Liver Fibrosis

Ciclesonide HFA

Phase 2

Rhinitis, Allergic, Seasonal

FOLFOX

Phase 2

Gastric Cancer

gefitinib (Iressa)

Phase 2

Neoplasms, Squamous Cell

Eplontersen

Phase 2

Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

AZD5213 + pregabalin

Phase 2

Diabetic Neuropathy, Painful; Diabetic Neuropathies

RDEA3170

Phase 2

Gout and Asymptomatic Hyperuricemia

AZD1446

Phase 2

Mild to Moderate Alzheimer's Disease

AZD5863

Phase 2

Gastric Cancer

AZD3470

Phase 2

Advanced Solid Tumors That Are MTAP Deficient

AZD4877

Phase 2

Bladder Cancer

AZD5148

Phase 2

Clostridioides Difficile Infection

CIN-107

Phase 2

Hypertension

AZD3632

Phase 2

Acute Lymphoblastic Leukaemia

Adavosertib

Phase 2

Uterine Serous Carcinoma

AZD1981

Phase 2

Chronic Obstructive Pulmonary Disease

MEDI7183 low dose

Phase 2

Ulcerative Colitis

AZD8233

Phase 2

Dyslipidaemia

AZD0530

Phase 2

Ovarian Neoplasms

AZD4144

Phase 2

Sepsis

AZD4956

Phase 2

Solid Tumours

Glipizide

Phase 2

Type II Diabetes Mellitus

AZD0516

Phase 2

Metastatic Prostate Cancer

Acalabrutinib monotherapy

Phase 2

Mantle-cell Lymphoma

MEDI4736 in combination with nab-paclitaxel and gemcitabine

Phase 2

Metastatic Pancreatic Ductal Adenocarcinoma

Atirmociclib

Phase 2

Advanced Breast Cancer

AZD6234

Phase 2

Endocrinology

Datopotamab Deruxtecan (Dato-DXd)

Phase 2

Carcinoma, Non-Small-Cell Lung

AZD7325

Phase 2

Anxiety Disorders

AZD6244

Phase 2

Metastatic Colorectal Cancer

AZD5069

Phase 2

Bronchiectasis

CIN-107 2 mg dosing

Phase 2

Primary Aldosteronism

exenatide once monthly suspension

Phase 2

Type 2 Diabetes

Oleclumab

Phase 2

Non-Small Cell Lung Cancer

AZD9773

Phase 2

Severe Sepsis

Nab-paclitaxel+carboplatin

Phase 2

Non-small Cell Lung Cancer NSCLC

Amivantamab

Phase 2

Non-Small Cell Lung Cancer (NSCLC)

Aclidinium Bromide/Formoterol Fumarate 400/12μg BID

Phase 2

Pulmonary Disease, Chronic Obstructive

AZD8848

Phase 2

Allergic Rhinitis

Zibotentan

Phase 2

Chronic Kidney Disease

Drug: carboplatin

Phase 2

Ovarian Cancer

ZD4054 15 mg

Phase 2

Prostate Cancer

Hydrochlorothiazide

Phase 2

Type 2 Diabetes Mellitus

Venetoclax

Phase 2

Mantle Cell Lymphoma (MCL)

AZD0305

Phase 2

Multiple Myeloma

[18F]AZD4694

Phase 2

Alzheimer's Disease

Verinurad

Phase 2

Heart Failure With Preserved Ejection Fraction (HFpEF)

AZD5672

Phase 2

Rheumatoid Arthritis

AZD2281

Phase 2

Ovarian Carcinoma

Zibotentan + dapagliflozin

Phase 2

Liver Cirrhosis

tralokinumab cohort 1

Phase 2

Idiopathic Pulmonary Fibrosis

Anastrazole

Phase 2

Breast Cancer

Market-Implied Move
Regulatory Approvals

Frequently asked questions

What is in ASTRAZENECA PLC's drug pipeline?

CatalystAlert tracks 303 drug candidates in ASTRAZENECA PLC's (AZNCF) pipeline across Phase 3, Phase 2. Its lead program is candsartan cilexetil (Phase 3). Each drug's phase, indication and upcoming catalysts are listed on this page.

When is ASTRAZENECA PLC's next FDA catalyst?

ASTRAZENECA PLC's (AZNCF) next tracked catalyst is a Phase 2 expected July 8, 2026. See the catalyst timeline on this page for the full schedule of PDUFA dates, trial readouts and FDA events.

How do I track AZNCF biotech catalysts?

Add AZNCF to your CatalystAlert watchlist for alerts ahead of each catalyst, and follow ASTRAZENECA PLC's live catalyst calendar, drug pipeline and clinical-trial timeline on this page — sourced from ClinicalTrials.gov, FDA and SEC filings.

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Data is aggregated from public sources (FDA, SEC, ClinicalTrials.gov). While we strive for accuracy, information may be incomplete, delayed, or contain errors. Terms apply