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BioPharma Dive
High ImpactOriginal article

Roche scraps two Ionis-partnered Huntington’s drugs

Data ReadoutnegativetominersenNegative
AI Analysis

Summary

Roche terminated development of two Ionis-partnered Huntington's disease drugs after tominersen failed to show disease progression delay in a clinical trial and a second candidate was scrapped due to animal safety signals.

Clinical Trial Data

Primary Endpoint

Not Met

Outcome Details

Tominersen failed to delay disease progression in one trial. A second Huntington's drug study was terminated due to safety signal in animal testing.

Importance:8/10
Sentiment:
-0.95
Huntington's diseaseclinical failurepartnershipdrug terminationsafety concern
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Published by BioPharma Dive on July 9, 2026 8:53 PM

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