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Roche Holding AG

RHHBY
$328.74B
Mega Cap
NYSEBiotechnology🇨🇭Europe103.2K employees
Website

Drugs in Pipeline

440

Phase 3 Programs

274

Upcoming Catalysts

110

Next Catalyst

Apr 30, 2026

Tomorrow

Market Overview

Stock performance and key metrics

RHHBY News
Catalyst Timeline

113 upcoming, 7 past

Phase 3Next
Positive

Vincristine Phase 3 Results Expected

Apr 30, 2026Vincristine1,000

Primary completion for Vincristine trial (NCT03274492) in Diffuse Large B-Cell Lymphoma

Met primary endpoint; significantly reduced relapses versus standard of care to approximately one every 17 years

Source
Phase 3

Prednisone Phase 3 Results Expected

Apr 30, 2026Prednisone1,000

Primary completion for Prednisone trial (NCT03274492) in Diffuse Large B-Cell Lymphoma

Source
Phase 3

Polatuzumab Vedotin Phase 3 Results Expected

Apr 30, 2026Polatuzumab Vedotin1,000

Primary completion for Polatuzumab Vedotin trial (NCT03274492) in Diffuse Large B-Cell Lymphoma

Source
Phase 3

Cyclophosphamide Phase 3 Results Expected

Apr 30, 2026Cyclophosphamide1,000

Primary completion for Cyclophosphamide trial (NCT03274492) in Diffuse Large B-Cell Lymphoma

Source
Phase 3

Rituximab Phase 3 Results Expected

Apr 30, 2026Rituximab1,000

Primary completion for Rituximab trial (NCT03274492) in Diffuse Large B-Cell Lymphoma

Source
Phase 3
Negative

Doxorubicin Phase 3 Results Expected

Apr 30, 2026Doxorubicin1,000

Primary completion for Doxorubicin trial (NCT03274492) in Diffuse Large B-Cell Lymphoma

Failed to demonstrate muscle-building efficacy; Phase III trials will not be initiated

Source
Other

Other

May 1, 2026

Roche announces the appointment of Mark Dawson, M.D., Ph.D., as Head of Roche Pharma Research and Early Development, effective 1 May 2026, with a concurrent position on the Enlarged Corporate Executive Committee.

106 more catalysts beyond 14 days

Start a 48h free trial to see all upcoming catalysts

Pro
Drug Pipeline

Paclitaxel

Phase 3

Ovarian Cancer

RO7204239

Phase 3

Obesity

trastuzumab (Herceptin®)

Phase 3

Breast Cancer

mycophenolate mofetil [CellCept]

Phase 3

Myasthenia Gravis Generalised

Lenvatinib

Phase 3

Unresectable Hepatocellular Carcinoma

Eculizumab

Phase 3

Paroxysmal Nocturnal Hemoglobinuria

Entecavir

Phase 3

Pediatric Immuno-Tolerant Chronic Hepatitis B

Mosunetuzumab

Phase 3

Non-Hodgkin Lymphoma

Prasinezumab

Phase 3

Parkinsons Disease

Dalcetrapib (RO4607381)

Phase 3

Coronary Heart Disease

FEC Chemotherapy

Phase 3

Breast Cancer

Darbepoetin alfa

Phase 3

Anemia

Interferon beta-1a

Phase 3

Relapsing Multiple Sclerosis

Carboplatin

Phase 3

Breast Cancer

Etoposide

Phase 3

Small Cell Lung Carcinoma

Mycophenolate Mofetil

Phase 3

Pemphigus Vulgaris

Folic acid or folate

Phase 3

Rheumatoid Arthritis

Evidence-based medical care for Acute Coronary Syndrome

Phase 3

Coronary Heart Disease

Vincristine

Phase 3

Non-Hodgkin's Lymphoma

Tiragolumab

Phase 3

Small Cell Lung Cancer

methoxy polyethylene glycol-epoetin beta [RO0503821, Mircera]

Phase 3

Anemia

methylprednisolone

Phase 3

Rheumatoid Arthritis

Vamikibart

Phase 3

Diabetic Macular Edema

Ribavirin

Phase 3

Hepatitis C, Chronic

Factor VIII (FVIII)

Phase 3

Hemophilia A

Pralsetinib

Phase 3

RET-fusion Non Small Cell Lung Cancer

Cabozantinib

Phase 3

Carcinoma, Non-Small-Cell Lung

Anti-VEGF Therapy

Phase 3

Neovascular Age-related Macular Degeneration

epoetin alfa or beta

Phase 3

Anemia

Zidovudine

Phase 3

HIV Infections

Remdesivir

Phase 3

COVID-19 Pneumonia

Polatuzumab Vedotin

Phase 3

Non-Hodgkin's Lymphoma

r-HuEPO

Phase 3

Anemia

Fingolimod

Phase 3

Relapsing-Remitting Multiple Sclerosis

Teriflunomide

Phase 3

Relapsing Multiple Sclerosis

Sefaxersen (RO7434656)

Phase 3

Primary IgA Nephropathy

tocilizumab [RoActemra]

Phase 3

Rheumatoid Arthritis

Standard DMARDs (Disease Modifying Anti Rheumatic Drugs)

Phase 3

Rheumatoid Arthritis

Tocilizumab (TCZ)

Phase 3

Rheumatoid Arthritis

Valganciclovir CMV Prophylaxis

Phase 3

Cytomegalovirus Infections

Neo-adjuvant chemotherapy

Phase 3

Breast Cancer

Enfuvirtide

Phase 3

HIV Infections

Pertuzumab

Phase 3

Breast Cancer

Taxane-based chemotherapy

Phase 3

Breast Cancer

Cyclosporine

Phase 3

Renal Transplantation

23-PPV

Phase 3

Multiple Sclerosis, Relapsing-Remitting

FAP IL2V

Phase 3

Cancer

Alimta or Taxotere

Phase 3

Non-Small Cell Lung Cancer

Oxaliplatin 130 mg/m^2

Phase 3

Colorectal Cancer

Non-steroidal anti-inflammatory drugs (NSAIDs)

Phase 3

Juvenile Idiopathic Arthritis

chlorambucil

Phase 3

Lymphocytic Leukemia, Chronic

5-Fluoruracil

Phase 3

Gastric Cancer

Giredestrant

Phase 3

Endometrial Cancer

Oseltamivir IV

Phase 3

Influenza

Sorafenib

Phase 3

Carcinoma, Hepatocellular

Interferon alfa 2a [Roferon]

Phase 3

Renal Cell Cancer

Disease-modifying anti-rheumatic drugs

Phase 3

Rheumatoid Arthritis

Becavizumab

Phase 3

Hepatocellular Carcinoma

Azathioprine

Phase 3

Rheumatoid Arthritis

Letrozole

Phase 3

Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer

Crizotinib

Phase 3

Neoplasms

Bitopertin

Phase 3

Beta-Thalassemia

Pegylated Interferon Alfa-2a

Phase 3

Chronic Myelogenous Leukemia

Pembrolizumab

Phase 3

Non-small Cell Lung Cancer (NSCLC)

Divarasib

Phase 3

Non-Small Cell Lung Cancer

Rituximab SC

Phase 3

Non-Hodgkin's Lymphoma

saquinavir [Invirase]

Phase 3

HIV Infections

Optimized background antiretroviral regimen (OB)

Phase 3

HIV Infections

Permitted DMARDs

Phase 3

Rheumatoid Arthritis

Adalimumab

Phase 3

Ulcerative Colitis

exenatide

Phase 3

Diabetes Mellitus Type 2

Ocrelizumab IV

Phase 3

Relapsing Multiple Sclerosis

bitopertin [RO4917838] level 1

Phase 3

Schizophrenia

MTX

Phase 3

Rheumatoid Arthritis

Antipsychotics

Phase 3

Schizophrenia

Pegylated interferon (PEG-IFN) alfa-2a, 180 mcg

Phase 3

Hepatitis B, Chronic

Dacarbazine

Phase 3

Malignant Melanoma

rFVIIa

Phase 3

Hemophilia A

Taxotere

Phase 3

Breast Cancer

Fluoropyrimidine-based Chemotherapy

Phase 3

Colorectal Cancer

CDK4/6i

Phase 3

Breast Cancer

PDS Implant Pre-Filled with 100 mg/mL Ranibizumab

Phase 3

Diabetic Retinopathy

CMF

Phase 3

Breast Cancer

Doxorubicin

Phase 3

Diffuse Large B-Cell Lymphoma, Lymphoma Follicular

Stavudine

Phase 3

HIV Infections

temozolomide

Phase 3

Glioblastoma Multiforme

Ganciclovir

Phase 3

Cytomegalovirus Retinitis

tocilizumab SC

Phase 3

Rheumatoid Arthritis

Lamivudine

Phase 3

HIV Infections

PDS Implant with Ranibizumab 100 mg/mL

Phase 3

Neovascular Age-Related Macular Degeneration

Erlotinib

Phase 3

Non-Squamous Non-Small Cell Lung Cancer

satralizumab

Phase 3

Neuromyelitis Optica Spectrum Disorder

MMF

Phase 3

Lupus Nephritis

interferon-a-2a

Phase 3

Lymphoma

Baloxavir Marboxil

Phase 3

Influenza

TRO19622

Phase 3

Amyotrophic Lateral Sclerosis

XELOX

Phase 3

Colorectal Cancer

Standard adjuvant chemotherapy

Phase 3

Breast Cancer

DMARD

Phase 3

Rheumatoid Arthritis

Sunitinib

Phase 3

Renal Cell Carcinoma

Mycophenolate Mofetil 2 g/Day

Phase 3

Pemphigus Vulgaris (PV)

Lebrikizumab

Phase 3

Asthma

Faricimab

Phase 3

Wet Macular Degeneration

Pegylated-interferon Alfa-2a

Phase 3

Hepatitis C, Chronic

Standard chemotherapy

Phase 3

Breast Cancer

von Willebrand Factor (VWF) Concentrates

Phase 3

Von Willebrand Disease, Type 3

Oral Corticosteroids

Phase 3

Rheumatoid Arthritis

Prednisone

Phase 3

Lymphoma

valganciclovir [Valcyte]

Phase 3

Cytomegalovirus Infections

Acetaminophen/ Paracetamol

Phase 3

Childhood Idiopathic Nephrotic Syndrome

Corticosteroids

Phase 3

Breast Cancer

Antihistamine

Phase 3

Multiple Sclerosis

Lapatinib

Phase 3

Breast Cancer

epoetin

Phase 3

Anemia

Human Coagulation Factor VIII

Phase 3

Hemophilia A

Nab-paclitaxel

Phase 3

Non-Small-Cell Lung

fusidic acid [Verutex]

Phase 3

Non-Small Cell Lung Cancer

Risdiplam

Phase 3

Muscular Atrophy, Spinal

Ocrelizumab

Phase 3

Multiple Sclerosis

Pegylated Interferon (PEG-IFN) alfa-2a

Phase 3

Hepatitis D, Chronic

Enzalutamide

Phase 3

Prostatic Neoplasms, Castration-Resistant

oseltamivir

Phase 3

Influenza, Human

Gemcitabine (Chemotherapy)

Phase 3

Ovarian Cancer

Second-Line Chemotherapy

Phase 3

Non-Squamous Non-Small Cell Lung Cancer

Nelfinavir mesylate

Phase 3

HIV Infections

Zalcitabine

Phase 3

HIV Infections

Efavirenz

Phase 3

HIV Infections

Atezolizumab (MPDL3280A) [TECENTRIQ], an engineered anti-PDL1 antibody

Phase 3

Non-Squamous Non-Small Cell Lung Cancer, Squamous Non-Small Cell Lung Cancer

Etrozulimab

Phase 3

Ulcerative Colitis

Vinflunine

Phase 3

Bladder Cancer

Neoral

Phase 3

Kidney Transplantation

Gantenerumab

Phase 3

Alzheimer's Disease

PDS Implant filled with 100 mg/mL Ranibizumab

Phase 3

Neovascular Age-Related Macular Degeneration

Fulvestrant

Phase 3

Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer

anti-IL-2R

Phase 3

Kidney Transplantation

Endocrine Therapy of Physician's Choice

Phase 3

Early Breast Cancer

Delavirdine mesylate

Phase 3

HIV Infections

Chemotherapy (Induction Period)

Phase 3

Non-Hodgkin's Lymphoma

Fludarabine

Phase 3

Lymphocytic Leukemia, Chronic

tenofovir

Phase 3

Hepatitis D, Chronic

RO0503821 (1x/2 Weeks)

Phase 3

Anemia

pioglitazone

Phase 3

Diabetes Mellitus Type 2

Olesoxime

Phase 3

Muscular Atrophy, Spinal

Riluzole

Phase 3

Amyotrophic Lateral Sclerosis

Astegolimab

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Vinorelbine

Phase 3

Non-Small Cell Lung Cancer

bitopertin [RO4917838]

Phase 3

Schizophrenia

Atezolizumab (MPDL3280A), an engineered anti-programmed death-ligand 1 (anti-PD-L1) antibody

Phase 3

Squamous Non-Small Cell Lung Cancer

Mycophenolate mofetil (MMF)

Phase 3

Lupus Nephritis

5-Fluorouracil

Phase 3

Gastric Cancer

cyclosporine A (CsA)

Phase 3

Heart Transplantation

Bendamustine

Phase 3

Chronic Lymphocytic Leukemia

Platinum chemotherapy (cisplatin or carboplatin)

Phase 3

Non-Squamous Non-Small Cell Lung Cancer

Irinotecan

Phase 3

Colorectal Cancer

Pertuzumab IV

Phase 3

Early Breast Cancer

Venetoclax

Phase 3

Chronic Lymphocytic Leukemia

RO7234292 (RG6042)

Phase 3

Huntington Disease

Epirubicin

Phase 3

Breast Cancer

Regorafenib

Phase 3

Colorectal Cancer

Tacrolimus

Phase 3

Primary Membranous Nephropathy

trastuzumab [Herceptin]

Phase 3

Breast Cancer

Acitretin

Phase 3

HIV Infections

Cyclophosphamide, Hydroxydaunorubicin, Oncovin, Prednisone/Prednisolone (CHOP)

Phase 3

Diffuse Large B-Cell Lymphoma, Non-Hodgkin's Lymphoma

Ranibizumab (10 mg/mL)

Phase 3

Neovascular Age-related Macular Degeneration

insulin glargine

Phase 3

Diabetes Mellitus Type 2

Lenalidomide

Phase 3

Relapsed or Refractory Follicular Lymphoma, Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Nonbiologic DMARDs of investigator's choice

Phase 3

Rheumatoid Arthritis

Tocilizumab 162 mg

Phase 3

Rheumatoid Arthritis

Optional Endocrine Therapy of Investigator's Choice

Phase 3

Metastatic Breast Cancer

Epoetin alfa

Phase 3

Anemia

5-Fluorouracil (5-FU)

Phase 3

Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma or Esophageal Carcinoma

Leucovorin calcium

Phase 3

Colorectal Cancer

5 FU

Phase 3

Neoplasms

Intravitreal Ranibizumab 0.5 mg Injection

Phase 3

Diabetic Macular Edema

Treatment of physician's choice

Phase 3

Breast Cancer

Oxaliplatin

Phase 3

Colorectal Cancer

montelukast [Singulair]

Phase 3

Asthma

Non-Biologic DMARDs

Phase 3

Rheumatoid Arthritis

rHuPH20

Phase 3

Non-Small Cell Lung Cancer

Tociluzumab

Phase 3

Relapsed or Refractory Follicular Lymphoma

Infliximab

Phase 3

Ulcerative Colitis

Fluorouracil

Phase 3

Gastric Cancer

Vemurafenib

Phase 3

Melanoma

Ipatasertib

Phase 3

Triple-Negative Breast Cancer

Ranibizumab

Phase 3

Diabetic Macular Edema

Emicizumab

Phase 3

Hemophilia A

Afimkibart

Phase 3

Crohns Disease

Docetaxel

Phase 3

Non-Small Cell Lung Cancer

tocilizumab [RoActemra/Actemra]

Phase 3

Rheumatoid Arthritis

Trastuzumab

Phase 3

Breast Cancer

Rituximab

Phase 3

Rheumatoid Arthritis

Atezolizumab

Phase 3

Carcinoma, Hepatocellular

Methoxy polyethylene glycol-epoetin beta (C.E.R.A.)

Phase 3

Anemia

Mircera

Phase 3

Anemia

erlotinib [Tarceva]

Phase 3

Non-Small Cell Lung Cancer

Saquinavir

Phase 3

HIV Infections

Obinutuzumab

Phase 3

Chronic Lymphocytic Leukemia (CLL)

rituximab [MabThera/Rituxan]

Phase 3

Rheumatoid Arthritis

Cyclophosphamide

Phase 3

Breast Cancer

liposomal doxorubicin

Phase 3

Ovarian Cancer

Omalizumab

Phase 3

Nasal Polyps

csDMARDs

Phase 3

Rheumatoid Arthritis

pertuzumab [Perjeta]

Phase 3

Breast Cancer

tocilizumab

Phase 3

Rheumatoid Arthritis

bevacizumab [Avastin]

Phase 3

Non-Squamous Non-Small Cell Lung Cancer

ritonavir

Phase 3

HIV Infections

Etrolizumab

Phase 3

Crohn Disease

leucovorin

Phase 3

Colorectal Cancer

Epoetin beta

Phase 3

Anemia

Lurbinectedin

Phase 3

Small-Cell Lung Cancer

taspoglutide

Phase 3

Diabetes Mellitus Type 2

Bevacizumab

Phase 3

Carcinoma, Hepatocellular

Atezolizumab (MPDL3280A), an engineered anti-PDL1 antibody

Phase 3

Triple-Negative Breast Cancer

Ibandronate

Phase 3

Post-Menopausal Osteoporosis

methotrexate

Phase 3

Rheumatoid Arthritis

Entrectinib

Phase 3

Solid Tumors

peginterferon alfa-2a [Pegasys]

Phase 3

Hepatitis B, Chronic

Methoxy Polyethylene Glycol-Epoetin Beta

Phase 3

Anemia

mycophenolate mofetil (CellCept)

Phase 3

Myasthenia Gravis, Generalized

Onartuzumab

Phase 3

Glioblastoma

Pirfenidone

Phase 3

Lung Diseases, Interstitial

Atezolizumab (MPDL3280A), an engineered anti-PD-L1 antibody

Phase 3

Carcinoma, Non-Squamous Non-Small Cell Lung

Capecitabine

Phase 3

Gastric Cancer

Fixed Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Use (PH FDC SC)

Phase 3

Early Breast Cancer

Trastuzumab IV

Phase 3

HER2-positive Early Breast Cancer

Other Combination Anti-Cancer Therapies

Phase 3

Solid Tumors

Valganciclovir

Phase 3

Cytomegalovirus Infections

Filgrastim

Phase 3

Triple-negative Breast Cancer

methoxy polyethylene glycol-epoetin beta [Mircera]

Phase 3

Anemia

Herceptin

Phase 3

Breast Cancer

Trastuzumab Emtansine

Phase 3

Breast Cancer

Gemcitabine

Phase 3

Pancreatic Cancer

Fenebrutinib

Phase 3

Relapsing Multiple Sclerosis

Dexamethasone

Phase 3

Idiopathic Thrombocytopenic Purpura

Glofitamab

Phase 3

Diffuse Large B-cell Lymphoma

Alectinib

Phase 3

Non-Small Cell Lung Cancer

capecitabine [Xeloda]

Phase 3

Colorectal Cancer

Peginterferon alfa-2a

Phase 3

Carcinoma, Hepatocellular

Cladribine

Phase 3

Lymphocytic Leukemia, Chronic

metformin

Phase 3

Diabetes Mellitus Type 2

ibandronate [Bonviva/Boniva]

Phase 3

Post-Menopausal Osteopenia

Trontinemab

Phase 3

Alzheimers Disease

Aflibercept

Phase 3

Diabetic Macular Edema

RO7239361

Phase 3

Duchenne Muscular Dystrophy

Sitagliptin

Phase 3

Diabetes Mellitus Type 2

aleglitazar

Phase 3

Diabetes Mellitus Type 2

Alectnib

Phase 3

Carcinoma, Non-Small-Cell Lung

Chemotherapy

Phase 3

Non-Small Cell Lung Cancer

Inavolisib

Phase 3

Breast Cancer

Leucovorin (LV)

Phase 3

Colorectal Cancer

CHOP

Phase 3

Lymphoma, Large B-Cell, Diffuse

rituximab [MabThera]

Phase 3

Rheumatoid Arthritis

RO4917838

Phase 3

Schizophrenia

Baseline Treatment

Phase 3

Neuromyelitis Optica (NMO)

Acetaminophen/Paracetamol

Phase 3

Systemic Lupus Erythematosus

Phesgo

Phase 3

Locally Advanced or Metastatic Breast Cancer

Fludarabine Phosphate

Phase 3

Chronic Lymphocytic Leukemia

methoxy polyethylene glycol-epoetin beta [C.E.R.A.]

Phase 3

Anemia

Pemetrexed

Phase 3

Carcinoma, Non-Small-Cell Lung

Ortho-Novum® 1/35

Phase 3

Rheumatoid Arthritis

PEGASYS

Phase 3

Hepatitis C, Chronic

Cisplatin

Phase 3

Nasopharyngeal Cancer

orlistat [Xenical]

Phase 3

Obesity

aleglitazar+metformin

Phase 3

Diabetes Mellitus Type 2

dalcetrapib

Phase 3

Coronary Heart Disease

Palbociclib

Phase 3

Breast Cancer

Tiragolumab and Atezolizumab

Phase 3

Cancer

Cobimetinib

Phase 3

Melanoma

DMARDs

Phase 3

Rheumatoid Arthritis

MabThera/Rituxan

Phase 3

Rheumatoid Arthritis

RO7234292

Phase 3

Huntingtons Disease

Onartuzumab [MetMAb]

Phase 3

Non-Small Cell Lung Cancer

epoetin beta [NeoRecormon]

Phase 3

Anemia

Crovalimab

Phase 3

Atypical Hemolytic Uremic Syndrome

Dual Integrin Antagonist

Phase 2

Asthma

RO4917523 1.5 mg

Phase 2

Major Depressive Disorder

Semaglutide

Phase 2

Type 2 Diabetes Mellitus

Atezolizumab Cohort 7

Phase 2

Solid Tumors

boceprevir

Phase 2

Hepatitis C, Chronic

Abemaciclib

Phase 2

Ovarian Cancer

RO7247669

Phase 2

Melanoma

enfuvirtide [Fuzeon]

Phase 2

HIV Infections

Tiragolumab and Atezolizumab IV FDC

Phase 2

PD-L1-selected Solid Tumors

Ro 24-7429

Phase 2

Sarcoma, Kaposi

RG7314

Phase 2

Autism Spectrum Disorder

Tociliuzumab

Phase 2

COVID-19 Pneumonia

TCS Cream

Phase 2

Atopic Dermatitis

Tobemstomig

Phase 2

Urothelial Cancer

antibody induction

Phase 2

Kidney Transplantation

Onartuzumab (MetMAb)

Phase 2

Gastric Cancer

Standard antipsychotic therapy

Phase 2

Schizophrenia

RO6864018

Phase 2

Hepatitis B, Chronic

RO5093151

Phase 2

Hypertension, Glaucoma, Open-Angle

Induction- PF-06480605 50 mg SC Q4W

Phase 2

Moderate to Severe Ulcerative Colitis

RO7268489

Phase 2

Progressive Multiple Sclerosis

LABA

Phase 2

Asthma

vismodegib

Phase 2

Basal Cell Carcinoma

RO4588161

Phase 2

Hepatitis C, Chronic

PEGPH20

Phase 2

Pancreatic Adenocarcinoma

FOLFIRI

Phase 2

Colorectal Cancer

Olaparib

Phase 2

Cancer of Unknown Primary Site

RO4998452

Phase 2

Diabetes Mellitus Type 2

RO4602522

Phase 2

Alzheimer's Disease

ribavirin [Copegus]

Phase 2

Hepatitis C, Chronic

Everolimus

Phase 2

Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer

Zifibancimig

Phase 2

Macular Degeneration

Anastrozole

Phase 2

Early Breast Cancer

Mericitabine

Phase 2

Hepatitis C

Lomustine

Phase 2

Glioblastoma

Induction Chemotherapy

Phase 2

Breast Cancer

AT-527

Phase 2

COVID-19

Olesoxime (TRO19622)

Phase 2

Chemotherapy-Induced Peripheral Neuropathy

capecitabine (Xeloda®)

Phase 2

Breast Cancer

Standard platinum-based chemotherapy

Phase 2

Non-Small Cell Lung Cancer

SGN-LIV1A

Phase 2

Metastatic Breast Cancer

Actos

Phase 2

Diabetes Mellitus Type 2

bevacizumab (Avastin)

Phase 2

Liver Cancer

First line chemotherapy

Phase 2

Mantle Cell Lymphoma

Folic Acid

Phase 2

Rheumatoid Arthritis

Erythropoietin Beta

Phase 2

Myelodysplastic Syndromes

PRM-151

Phase 2

Idiopathic Pulmonary Fibrosis

RO7126209

Phase 2

Alzheimers Disease

Metronidazole Actavis

Phase 2

Non-Squamous Non-Small Cell Lung Cancer

Tominersen

Phase 2

Huntington Disease

RO5027838

Phase 2

Diabetes Mellitus Type 2

RO7490677

Phase 2

Primary Myelofibrosis

Mycophenolate Mofetil/Mycophenolic Acid

Phase 2

Lupus Nephritis

RO5313534

Phase 2

Alzheimer's Disease

RO6889450

Phase 2

Schizophrenia, Schizoaffective Disorder

Epidoxorubicin

Phase 2

Breast Cancer

Balovaptan

Phase 2

Stress Disorders, Post-Traumatic

Carboplatin-based chemotherapy

Phase 2

Non-Small Cell Lung Cancer

Pegylated Interferon (Peginterferon) Alfa-2a

Phase 2

Hepatitis B, Chronic

Pravastatin

Phase 2

Dyslipidemia

Lomvastomig

Phase 2

Advanced or Metastatic Esophageal Squamous Cell Carcinoma

RG3421 120mg

Phase 2

Psoriasis

Standard taxane therapy

Phase 2

Breast Cancer

Doxycline

Phase 2

Non-Small Cell Lung Cancer

Ifosfamide

Phase 2

Mature B-Cell Non-Hodgkin Lymphoma

obinutuzumab (RO5072759)

Phase 2

Non-Hodgkin's Lymphoma

Iberdomide

Phase 2

Multiple Myeloma

RO5083945

Phase 2

Non-Squamous Non-Small Cell Lung Cancer

GC33

Phase 2

Carcinoma, Hepatocellular

fluorouracil (5FU)

Phase 2

Colorectal Cancer

RO5217790

Phase 2

Cervical Intraepithelial Neoplasia

RO4917523

Phase 2

Fragile X Syndrome

pralsetinib (BLU-667)

Phase 2

RET-altered Non Small Cell Lung Cancer

5-FU

Phase 2

Colorectal Cancer

ibandronate [Bondronat]

Phase 2

Pain; Bone Neoplasms; Neoplasm Metastasis

Mosunetuzumab (SC)

Phase 2

Follicular Lymphoma

RO4876904

Phase 2

Diabetes Mellitus Type 2

Crenezumab

Phase 2

Alzheimer Disease

Cevostamab

Phase 2

Multiple Myeloma

RO4917523 0.5 mg

Phase 2

Fragile X Syndrome

Erlotinib, escalating dose

Phase 2

Pancreatic Cancer

eloxatin

Phase 2

Colorectal Cancer

ANA598

Phase 2

HCV Infection

Copegus

Phase 2

Hepatitis C, Chronic

N-acetylcysteine

Phase 2

Idiopathic Pulmonary Fibrosis

OpRegen

Phase 2

Age-Related Macular Degeneration

Basmisanil

Phase 2

Schizophrenia

TRO40303

Phase 2

Acute Myocardial Infarctus

RG7774

Phase 2

Diabetic Retinopathy

RO7795081

Phase 2

Obesity or Overweight

RO5190591 (Danoprevir)

Phase 2

Hepatitis C, Chronic

RO4995819

Phase 2

Major Depressive Disorder

Abiraterone

Phase 2

Metastatic Castration-Resistant Prostate Cancer

P38 Inhibitor (4) 150mg

Phase 2

Rheumatoid Arthritis

Forimtamig

Phase 2

Relapsed or Refractory Multiple Myeloma

Inhaled corticposteroids (ICS)

Phase 2

Asthma

Experimental

Phase 2

Diabetic Neuropathy

fotemustine

Phase 2

Glioblastoma Multiforme

Investigator's choice of anti-cancer treatment (except immunotherapy)

Phase 2

Breast Cancer

Sham Procedure

Phase 2

Neovascularization, Choroidal

Atezolizumab [TECENTRIQ]

Phase 2

Lymphoma

Optimized Background ARVs

Phase 2

HIV Infections

Trastuzumab emtansine [Kadcyla]

Phase 2

Breast Cancer

Abacavir sulfate

Phase 2

HIV Infections

RO4905417

Phase 2

Coronary Heart Disease, Graft Occlusion, Vascular

Taxane (docetaxel or paclitaxel)

Phase 2

Breast Cancer

RO5190591

Phase 2

Hepatitis C, Chronic

Temozolomide (TMZ)

Phase 2

High Grade Glioma

Sildenafil

Phase 2

Idiopathic Pulmonary Fibrosis

NXT007

Phase 2

Hemophilia A

RO5459072

Phase 2

Sjogren's Syndrome

RAR Gamma

Phase 2

Emphysema

Alogabat

Phase 2

Angelman Syndrome

89Zr-Df-IAB22M2C

Phase 2

Non-Hodgkins Lymphoma

beta-lactam

Phase 2

Soft Tissue Infections

RO5185426

Phase 2

Malignant Melanoma

Mosunetuzumab Intravenous (IV)

Phase 2

Diffuse Large B-cell Lymphoma

Englumafusp alfa

Phase 2

Lymphoma, Non-Hodgkin

Rituxumab

Phase 2

B-cell Non-Hodgkin Lymphoma

SSRI

Phase 2

Obsessive-Compulsive Disorder

RO7269162

Phase 2

Alzheimer's Disease

Polatuzumab vedotin (Liquid)

Phase 2

Lymphoma

Ribociclib

Phase 2

Breast Cancer

RO7247669 2100 mg

Phase 2

Melanoma

Ocrelizumab Test Formulation

Phase 2

Multiple Sclerosis

Xeloda

Phase 2

Breast Cancer

C.E.R.A.

Phase 2

Anemia

cetuximab

Phase 2

Multiple Myeloma, Neoplasms

Taspoglutide 20mg

Phase 2

Diabetes Mellitus Type 2

Mosunetuzumab (IV)

Phase 2

B-cell Non-Hodgkin Lymphoma

RO6958688

Phase 2

Carcinoma, Non-Small-Cell Lung

Atezolizumab (MPDL3280A), an engineered anti-programmed death-ligand 1 (PD-L1) antibody

Phase 2

Breast Neoplasms

Trastuzumab emtansine [Kadcyla] 3.0 mg/kg

Phase 2

Metastatic Breast Cancer

RO4929097

Phase 2

Non-Squamous Non-Small Cell Lung Cancer

P38 Inhibitor (4)

Phase 2

Rheumatoid Arthritis

Ceftriaxone

Phase 2

Pneumonia, Bacterial

Didanosine

Phase 2

HIV Infections

Folinic Acid

Phase 2

Rectal Cancer

Levofolinic acid

Phase 2

Colorectal Cancer

Autogene Cevumeran

Phase 2

Muscle-invasive Urothelial Carcinoma

danoprevir + ritonavir

Phase 2

Hepatitis C, Chronic

Epothilone D

Phase 2

Breast Cancer

Pertuzumab and Trastuzumab Fixed-Dose Combination for Subcutaneous Administration (PH FDC SC)

Phase 2

HER2-Positive Early Breast Cancer

Interferon alfa-2a

Phase 2

Renal Cell Cancer

ZN-A-1041

Phase 2

Advanced Solid Tumors

Axitinib

Phase 2

Renal Cell Carcinoma

Nucleos(t)ide (NUC)

Phase 2

Hepatitis B, Chronic

GK Activator (2)

Phase 2

Diabetes Mellitus Type 2

Second line chemotherapy

Phase 2

Breast Cancer

RG1662

Phase 2

Down Syndrome

Rituximab IV

Phase 2

Lymphoma, Large B-Cell, Diffuse

Fulvestrant or an Aromatase Inhibitor (Physician Choice)

Phase 2

Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer

RO7046015

Phase 2

Parkinson's Disease

Atezolizumab (MPDL3280A) [TECENTRIQ]

Phase 2

Lymphoma, Follicular

Aromatase Inhibitor

Phase 2

Breast Cancer

Diphenhydramine hydrochloride (HCl)

Phase 2

Lupus Nephritis

Hormonal Therapy

Phase 2

Breast Cancer

DPP-IV Inhibitor

Phase 2

Diabetes Mellitus Type 2

Enfortumab Vedotin

Phase 2

Urothelial Carcinoma

PEGASYS [peginterferon alfa-2a]

Phase 2

Hepatitis B, Chronic

MSTT1041A

Phase 2

Asthma

RO7017773

Phase 2

Autism Spectrum Disorder (ASD)

RO 205-2349

Phase 2

Diabetes

Danoprevir

Phase 2

Hepatitis C, Chronic

Bevacizumab 15 mg/kg

Phase 2

Advanced Liver Cancers

RO5024048

Phase 2

Hepatitis C, Chronic

Regulatory Approvals
Data is aggregated from public sources (FDA, SEC, ClinicalTrials.gov). While we strive for accuracy, information may be incomplete, delayed, or contain errors. Terms apply