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Roche Holding AG

RHHBY
$316.38B
Mega Cap
NYSEBiotechnology🇨🇭Europe103.2K employees
Website

Drugs in Pipeline

497

Phase 3 Programs

270

Upcoming Catalysts

54

Next Catalyst

This month

Market Overview

Stock performance and key metrics

RHHBY News
Catalyst Timeline

58 upcoming, 10 past

Phase 2Next

Ocrelizumab Test Formulation Phase 2 Est. Readout

September 2026~Ocrelizumab Test Formulation193

Estimated primary completion for Ocrelizumab Test Formulation trial (NCT07074886) in Multiple Sclerosis. Topline data typically follows completion by weeks to months.

Source

57 more catalysts beyond 14 days

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How RHHBY's past catalysts played out

Drug Pipeline

RO7239361

Phase 3

Duchenne Muscular Dystrophy

RO7204239

Phase 3

Obesity

trastuzumab (Herceptin®)

Phase 3

Breast Cancer

mycophenolate mofetil [CellCept]

Phase 3

Myasthenia Gravis Generalised

Lenvatinib

Phase 3

Unresectable Hepatocellular Carcinoma

Eculizumab

Phase 3

Paroxysmal Nocturnal Hemoglobinuria

Pirfenidone

Phase 3

Lung Diseases, Interstitial

Atezolizumab (MPDL3280A), an engineered anti-PD-L1 antibody

Phase 3

Carcinoma, Non-Squamous Non-Small Cell Lung

Fixed Dose Combination of Pertuzumab and Trastuzumab for Subcutaneous Use (PH FDC SC)

Phase 3

Early Breast Cancer

Trastuzumab IV

Phase 3

HER2-positive Early Breast Cancer

Other Combination Anti-Cancer Therapies

Phase 3

Solid Tumors

Valganciclovir

Phase 3

Cytomegalovirus Infections

Filgrastim

Phase 3

Triple-negative Breast Cancer

methoxy polyethylene glycol-epoetin beta [Mircera]

Phase 3

Anemia

Herceptin

Phase 3

Breast Cancer

Trastuzumab Emtansine

Phase 3

Breast Cancer

Fenebrutinib

Phase 3

Relapsing Multiple Sclerosis

Glofitamab

Phase 3

Diffuse Large B-cell Lymphoma

Alectinib

Phase 3

Non-Small Cell Lung Cancer

capecitabine [Xeloda]

Phase 3

Colorectal Cancer

Peginterferon alfa-2a

Phase 3

Carcinoma, Hepatocellular

Cladribine

Phase 3

Lymphocytic Leukemia, Chronic

ibandronate [Bonviva/Boniva]

Phase 3

Post-Menopausal Osteopenia

Trontinemab

Phase 3

Alzheimers Disease

aleglitazar

Phase 3

Diabetes Mellitus Type 2

Alectnib

Phase 3

Carcinoma, Non-Small-Cell Lung

Chemotherapy

Phase 3

Non-Small Cell Lung Cancer

Inavolisib

Phase 3

Breast Cancer

Leucovorin (LV)

Phase 3

Colorectal Cancer

CHOP

Phase 3

Lymphoma, Large B-Cell, Diffuse

rituximab [MabThera]

Phase 3

Rheumatoid Arthritis

RO4917838

Phase 3

Schizophrenia

Baseline Treatment

Phase 3

Neuromyelitis Optica (NMO)

Acetaminophen/Paracetamol

Phase 3

Systemic Lupus Erythematosus

Phesgo

Phase 3

Locally Advanced or Metastatic Breast Cancer

Fludarabine Phosphate

Phase 3

Chronic Lymphocytic Leukemia

methoxy polyethylene glycol-epoetin beta [C.E.R.A.]

Phase 3

Anemia

Ortho-Novum® 1/35

Phase 3

Rheumatoid Arthritis

PEGASYS

Phase 3

Hepatitis C, Chronic

RO7771950

Phase 3

HER2-positive Breast Cancer

orlistat [Xenical]

Phase 3

Obesity

aleglitazar+metformin

Phase 3

Diabetes Mellitus Type 2

dalcetrapib

Phase 3

Coronary Heart Disease

Tiragolumab and Atezolizumab

Phase 3

Cancer

Cobimetinib

Phase 3

Melanoma

DMARDs

Phase 3

Rheumatoid Arthritis

MabThera/Rituxan

Phase 3

Rheumatoid Arthritis

RO7234292

Phase 3

Huntingtons Disease

Onartuzumab [MetMAb]

Phase 3

Non-Small Cell Lung Cancer

epoetin beta [NeoRecormon]

Phase 3

Anemia

Crovalimab

Phase 3

Atypical Hemolytic Uremic Syndrome

Entecavir

Phase 3

Pediatric Immuno-Tolerant Chronic Hepatitis B

Mosunetuzumab

Phase 3

Non-Hodgkin Lymphoma

Prasinezumab

Phase 3

Parkinsons Disease

Dalcetrapib (RO4607381)

Phase 3

Coronary Heart Disease

FEC Chemotherapy

Phase 3

Breast Cancer

Darbepoetin alfa

Phase 3

Anemia

Interferon beta-1a

Phase 3

Relapsing Multiple Sclerosis

Evidence-based medical care for Acute Coronary Syndrome

Phase 3

Coronary Heart Disease

Tiragolumab

Phase 3

Small Cell Lung Cancer

methoxy polyethylene glycol-epoetin beta [RO0503821, Mircera]

Phase 3

Anemia

methylprednisolone

Phase 3

Rheumatoid Arthritis

Vamikibart

Phase 3

Diabetic Macular Edema

Factor VIII (FVIII)

Phase 3

Hemophilia A

Pralsetinib

Phase 3

RET-fusion Non Small Cell Lung Cancer

Anti-VEGF Therapy

Phase 3

Neovascular Age-related Macular Degeneration

epoetin alfa or beta

Phase 3

Anemia

Zidovudine

Phase 3

HIV Infections

Remdesivir

Phase 3

COVID-19 Pneumonia

Polatuzumab Vedotin

Phase 3

Non-Hodgkin's Lymphoma

r-HuEPO

Phase 3

Anemia

Fingolimod

Phase 3

Relapsing-Remitting Multiple Sclerosis

Teriflunomide

Phase 3

Relapsing Multiple Sclerosis

Sefaxersen (RO7434656)

Phase 3

Primary IgA Nephropathy

tocilizumab [RoActemra]

Phase 3

Rheumatoid Arthritis

Standard DMARDs (Disease Modifying Anti Rheumatic Drugs)

Phase 3

Rheumatoid Arthritis

Tocilizumab (TCZ)

Phase 3

Rheumatoid Arthritis

Valganciclovir CMV Prophylaxis

Phase 3

Cytomegalovirus Infections

Neo-adjuvant chemotherapy

Phase 3

Breast Cancer

Enfuvirtide

Phase 3

HIV Infections

Pertuzumab

Phase 3

Breast Cancer

Taxane-based chemotherapy

Phase 3

Breast Cancer

Cyclosporine

Phase 3

Renal Transplantation

23-PPV

Phase 3

Multiple Sclerosis, Relapsing-Remitting

FAP IL2V

Phase 3

Cancer

Alimta or Taxotere

Phase 3

Non-Small Cell Lung Cancer

Oxaliplatin 130 mg/m^2

Phase 3

Colorectal Cancer

Non-steroidal anti-inflammatory drugs (NSAIDs)

Phase 3

Juvenile Idiopathic Arthritis

chlorambucil

Phase 3

Lymphocytic Leukemia, Chronic

5-Fluoruracil

Phase 3

Gastric Cancer

Giredestrant

Phase 3

Endometrial Cancer

Oseltamivir IV

Phase 3

Influenza

Interferon alfa 2a [Roferon]

Phase 3

Renal Cell Cancer

Disease-modifying anti-rheumatic drugs

Phase 3

Rheumatoid Arthritis

Becavizumab

Phase 3

Hepatocellular Carcinoma

Azathioprine

Phase 3

Rheumatoid Arthritis

Crizotinib

Phase 3

Neoplasms

Bitopertin

Phase 3

Beta-Thalassemia

Pegylated Interferon Alfa-2a

Phase 3

Chronic Myelogenous Leukemia

Divarasib

Phase 3

Non-Small Cell Lung Cancer

Rituximab SC

Phase 3

Non-Hodgkin's Lymphoma

saquinavir [Invirase]

Phase 3

HIV Infections

Optimized background antiretroviral regimen (OB)

Phase 3

HIV Infections

Permitted DMARDs

Phase 3

Rheumatoid Arthritis

exenatide

Phase 3

Diabetes Mellitus Type 2

Ocrelizumab IV

Phase 3

Relapsing Multiple Sclerosis

bitopertin [RO4917838] level 1

Phase 3

Schizophrenia

MTX

Phase 3

Rheumatoid Arthritis

Antipsychotics

Phase 3

Schizophrenia

Pegylated interferon (PEG-IFN) alfa-2a, 180 mcg

Phase 3

Hepatitis B, Chronic

Prednisone/Prednisolone

Phase 3

Metastatic Prostate Cancer

Recombinant Hepatitis B Virus Vaccine

Phase 3

Hepatitis B

rFVIIa

Phase 3

Hemophilia A

Taxotere

Phase 3

Breast Cancer

Fluoropyrimidine-based Chemotherapy

Phase 3

Colorectal Cancer

CDK4/6i

Phase 3

Breast Cancer

PDS Implant Pre-Filled with 100 mg/mL Ranibizumab

Phase 3

Diabetic Retinopathy

CMF

Phase 3

Breast Cancer

Stavudine

Phase 3

HIV Infections

Ganciclovir

Phase 3

Cytomegalovirus Retinitis

tocilizumab SC

Phase 3

Rheumatoid Arthritis

Lamivudine

Phase 3

HIV Infections

PDS Implant with Ranibizumab 100 mg/mL

Phase 3

Neovascular Age-Related Macular Degeneration

Erlotinib

Phase 3

Non-Squamous Non-Small Cell Lung Cancer

satralizumab

Phase 3

Neuromyelitis Optica Spectrum Disorder

MMF

Phase 3

Lupus Nephritis

interferon-a-2a

Phase 3

Lymphoma

Baloxavir Marboxil

Phase 3

Influenza

TRO19622

Phase 3

Amyotrophic Lateral Sclerosis

XELOX

Phase 3

Colorectal Cancer

Standard adjuvant chemotherapy

Phase 3

Breast Cancer

DMARD

Phase 3

Rheumatoid Arthritis

Mycophenolate Mofetil 2 g/Day

Phase 3

Pemphigus Vulgaris (PV)

Lebrikizumab

Phase 3

Asthma

Faricimab

Phase 3

Wet Macular Degeneration

Pegylated-interferon Alfa-2a

Phase 3

Hepatitis C, Chronic

Standard chemotherapy

Phase 3

Breast Cancer

von Willebrand Factor (VWF) Concentrates

Phase 3

Von Willebrand Disease, Type 3

Oral Corticosteroids

Phase 3

Rheumatoid Arthritis

valganciclovir [Valcyte]

Phase 3

Cytomegalovirus Infections

bevacizumab, erlotinib

Phase 3

Colorectal Cancer

Acetaminophen/ Paracetamol

Phase 3

Childhood Idiopathic Nephrotic Syndrome

Corticosteroids

Phase 3

Breast Cancer

Antihistamine

Phase 3

Multiple Sclerosis

epoetin

Phase 3

Anemia

Human Coagulation Factor VIII

Phase 3

Hemophilia A

fusidic acid [Verutex]

Phase 3

Non-Small Cell Lung Cancer

Rituximab IV

Phase 3

Lymphoma, Large B-Cell, Diffuse

Risdiplam

Phase 3

Muscular Atrophy, Spinal

Ocrelizumab

Phase 3

Multiple Sclerosis

Pegylated Interferon (PEG-IFN) alfa-2a

Phase 3

Hepatitis D, Chronic

oseltamivir

Phase 3

Influenza, Human

Gemcitabine (Chemotherapy)

Phase 3

Ovarian Cancer

Second-Line Chemotherapy

Phase 3

Non-Squamous Non-Small Cell Lung Cancer

Nelfinavir mesylate

Phase 3

HIV Infections

Zalcitabine

Phase 3

HIV Infections

Efavirenz

Phase 3

HIV Infections

Atezolizumab (MPDL3280A) [TECENTRIQ], an engineered anti-PDL1 antibody

Phase 3

Non-Squamous Non-Small Cell Lung Cancer, Squamous Non-Small Cell Lung Cancer

Cevostamab

Phase 3

Multiple Myeloma

Etrozulimab

Phase 3

Ulcerative Colitis

Vinflunine

Phase 3

Bladder Cancer

Neoral

Phase 3

Kidney Transplantation

Gantenerumab

Phase 3

Alzheimer's Disease

PDS Implant filled with 100 mg/mL Ranibizumab

Phase 3

Neovascular Age-Related Macular Degeneration

anti-IL-2R

Phase 3

Kidney Transplantation

Endocrine Therapy of Physician's Choice

Phase 3

Early Breast Cancer

Delavirdine mesylate

Phase 3

HIV Infections

adefovir dipivoxil

Phase 3

Hepatitis B, Chronic

Chemotherapy (Induction Period)

Phase 3

Non-Hodgkin's Lymphoma

tenofovir

Phase 3

Hepatitis D, Chronic

RO0503821 (1x/2 Weeks)

Phase 3

Anemia

Atezolizumab

Phase 3

Triple-Negative Breast Cancer

Fluorouracil

Phase 3

HIV Infections

Olesoxime

Phase 3

Muscular Atrophy, Spinal

Riluzole

Phase 3

Amyotrophic Lateral Sclerosis

Astegolimab

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

bitopertin [RO4917838]

Phase 3

Schizophrenia

Atezolizumab (MPDL3280A), an engineered anti-programmed death-ligand 1 (anti-PD-L1) antibody

Phase 3

Squamous Non-Small Cell Lung Cancer

Mycophenolate mofetil (MMF)

Phase 3

Lupus Nephritis

5-Fluorouracil

Phase 3

Gastric Cancer

cyclosporine A (CsA)

Phase 3

Heart Transplantation

Platinum chemotherapy (cisplatin or carboplatin)

Phase 3

Non-Squamous Non-Small Cell Lung Cancer

Pertuzumab IV

Phase 3

Early Breast Cancer

Venetoclax

Phase 3

Chronic Lymphocytic Leukemia

RO7234292 (RG6042)

Phase 3

Huntington Disease

Epirubicin

Phase 3

Breast Cancer

Regorafenib

Phase 3

Colorectal Cancer

trastuzumab [Herceptin]

Phase 3

Breast Cancer

Acitretin

Phase 3

HIV Infections

Cyclophosphamide, Hydroxydaunorubicin, Oncovin, Prednisone/Prednisolone (CHOP)

Phase 3

Diffuse Large B-Cell Lymphoma, Non-Hodgkin's Lymphoma

Ranibizumab (10 mg/mL)

Phase 3

Neovascular Age-related Macular Degeneration

Nonbiologic DMARDs of investigator's choice

Phase 3

Rheumatoid Arthritis

Tocilizumab 162 mg

Phase 3

Rheumatoid Arthritis

Optional Endocrine Therapy of Investigator's Choice

Phase 3

Metastatic Breast Cancer

Epoetin alfa

Phase 3

Anemia

5-Fluorouracil (5-FU)

Phase 3

Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma or Esophageal Carcinoma

Leucovorin calcium

Phase 3

Colorectal Cancer

Methotrexate

Phase 3

Rheumatoid Arthritis

Gemcitabine

Phase 3

Metastatic HER2-Positive Breast Cancer

Rituximab

Phase 3

Large B-Cell Lymphoma

Trastuzumab

Phase 3

Breast Cancer

Ribavirin

Phase 3

Hepatitis C, Chronic

erlotinib hydrochloride

Phase 3

Lung Cancer

Fulvestrant

Phase 3

Breast Cancer

Bevacizumab

Phase 3

Melanoma

R-pola-mini-CHP

Phase 3

DLBCL

Obinutuzumab

Phase 3

Large B-cell Lymphoma

Bendamustine

Phase 3

Follicular Lymphoma

Capecitabine

Phase 3

Biliary Tract Cancer

pegylated interferon alpha2a

Phase 3

Chronic Hepatitis C

Letrozole 2.5mg

Phase 3

Ovarian Neoplasm Epithelial

tenecteplase

Phase 3

Myocardial Infarction

background treatment

Phase 3

Tubular Breast Cancer Stage II

PEGIntron plus ribavirin

Phase 3

Chronic Hepatitis C Virus Infection

Trastuzumab in combination with pertuzumab

Phase 3

Haematological Malignancy

Pegylated Interferon/ribavirin

Phase 3

Chronic Hepatitis C

Peginterferon alpha-2a (Pegasys®)

Phase 3

HIV Infections

Folate

Phase 3

Rheumatoid Arthritis

Zilebesiran

Phase 3

High Risk Cardiovascular Disease

epoetin beta (NeoRecormon ®)

Phase 3

Kidney Failure

Invirase

Phase 3

Directly Observed Therapy

sirolimus versus mycophenolate mofetil

Phase 3

Diabetes Mellitus, Type 1

Obinutuzumab administration

Phase 3

Membranous Nephropathy - PLA2R Induced

Peginterferon alfa-2a + Ribavirin

Phase 3

Chronic Hepatitis c

XELOXA

Phase 3

Colorectal Cancer

LHRH Agonist

Phase 3

Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer

emtricitabine/tenofovir

Phase 3

HIV Infections

Irinotecan (CPT-11)

Phase 3

Colorectal Cancer

Ribavirin "loading" dose given

Phase 3

Hepatitis C

TRUVADA (EMTRICITABINE + TENOFOVIR DF)

Phase 3

Hepatitis B

Solanezumab

Phase 3

Alzheimers Disease

modified FOLFOX6 + bevacizumab

Phase 3

Metastatic Colorectal Cancer

Folinic Acid, interferon-alpha

Phase 3

Rectal Cancer

5 FU

Phase 3

Neoplasms

Intravitreal Ranibizumab 0.5 mg Injection

Phase 3

Diabetic Macular Edema

Treatment of physician's choice

Phase 3

Breast Cancer

Non-Biologic DMARDs

Phase 3

Rheumatoid Arthritis

rHuPH20

Phase 3

Non-Small Cell Lung Cancer

Tociluzumab

Phase 3

Relapsed or Refractory Follicular Lymphoma

Onartuzumab (MetMAb)

Phase 3

Gastric Cancer

Infliximab

Phase 3

Ulcerative Colitis

Vemurafenib

Phase 3

Melanoma

Ipatasertib

Phase 3

Triple-Negative Breast Cancer

Ranibizumab

Phase 3

Diabetic Macular Edema

Emicizumab

Phase 3

Hemophilia A

Afimkibart

Phase 3

Crohns Disease

tocilizumab [RoActemra/Actemra]

Phase 3

Rheumatoid Arthritis

Methoxy polyethylene glycol-epoetin beta (C.E.R.A.)

Phase 3

Anemia

Mircera

Phase 3

Anemia

erlotinib [Tarceva]

Phase 3

Non-Small Cell Lung Cancer

Saquinavir

Phase 3

HIV Infections

rituximab [MabThera/Rituxan]

Phase 3

Rheumatoid Arthritis

liposomal doxorubicin

Phase 3

Ovarian Cancer

Omalizumab

Phase 3

Nasal Polyps

csDMARDs

Phase 3

Rheumatoid Arthritis

pertuzumab [Perjeta]

Phase 3

Breast Cancer

tocilizumab

Phase 3

Rheumatoid Arthritis

bevacizumab [Avastin]

Phase 3

Non-Squamous Non-Small Cell Lung Cancer

ritonavir

Phase 3

HIV Infections

Etrolizumab

Phase 3

Crohn Disease

Epoetin beta

Phase 3

Anemia

Lurbinectedin

Phase 3

Small-Cell Lung Cancer

taspoglutide

Phase 3

Diabetes Mellitus Type 2

Atezolizumab (MPDL3280A), an engineered anti-PDL1 antibody

Phase 3

Triple-Negative Breast Cancer

Ibandronate

Phase 3

Post-Menopausal Osteoporosis

Entrectinib

Phase 3

Solid Tumors

peginterferon alfa-2a [Pegasys]

Phase 3

Hepatitis B, Chronic

Methoxy Polyethylene Glycol-Epoetin Beta

Phase 3

Anemia

mycophenolate mofetil (CellCept)

Phase 3

Myasthenia Gravis, Generalized

Onartuzumab

Phase 3

Glioblastoma

Dual Integrin Antagonist

Phase 2

Asthma

RO4917523 1.5 mg

Phase 2

Major Depressive Disorder

RO4995819

Phase 2

Major Depressive Disorder

Atezolizumab Cohort 7

Phase 2

Solid Tumors

boceprevir

Phase 2

Hepatitis C, Chronic

Abemaciclib

Phase 2

Ovarian Cancer

Bendamustine and subcutaneous rituximab

Phase 2

Aggressive Lymphoma

Levofolinic acid

Phase 2

Colorectal Cancer

Mesna

Phase 2

Lymphoma

Ro 24-7429

Phase 2

Sarcoma, Kaposi

mDCF

Phase 2

Anal Cancer

Doxorubicine

Phase 2

Untreated T-cell Angioimmunoblastic Lymphoma

Topical Corticosteroid Creams (Triamcinolone acetonide 0.1% and Hydrocortisone 2.5%)

Phase 2

Atopic Dermatitis

YL201

Phase 2

Thoracic Neoplasms, Lung Diseases, Small Cell Lung Carcinoma

2-CdA

Phase 2

Lymphoma of Mucosa-Associated Lymphoid Tissue

Polyenylphosphatidylcholine (PPC)

Phase 2

Hepatitis C

antibody induction

Phase 2

Kidney Transplantation

Standard antipsychotic therapy

Phase 2

Schizophrenia

Second line chemotherapy

Phase 2

Breast Cancer

RO6864018

Phase 2

Hepatitis B, Chronic

RO5093151

Phase 2

Hypertension, Glaucoma, Open-Angle

Englumafusp alfa

Phase 2

Lymphoma, Non-Hodgkin

RO7268489

Phase 2

Progressive Multiple Sclerosis

ZN-A-1041

Phase 2

Advanced Solid Tumors

RO4588161

Phase 2

Hepatitis C, Chronic

Fulvestrant or an Aromatase Inhibitor (Physician Choice)

Phase 2

Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer

RO7046015

Phase 2

Parkinson's Disease

Aromatase Inhibitor

Phase 2

Breast Cancer

Diphenhydramine hydrochloride (HCl)

Phase 2

Lupus Nephritis

Hormonal Therapy

Phase 2

Breast Cancer

Mericitabine

Phase 2

Hepatitis C

Rituximab + CHOP chemotherapy

Phase 2

Primary Gastric Diffuse-Large B-Cell Lymphoma

Induction Chemotherapy

Phase 2

Breast Cancer

docetaxel, capecitabine

Phase 2

Metastatic Breast Cancer

PRM-151

Phase 2

Idiopathic Pulmonary Fibrosis

Tobemstomig

Phase 2

Urothelial Cancer

Obinutuzumab and Pixantrone

Phase 2

Lymphoma, Non-Hodgkin

Actos

Phase 2

Diabetes Mellitus Type 2

capecitabine (Xeloda)

Phase 2

Rectal Cancer

PHY906

Phase 2

Pancreatic Cancer

Erythropoietin Beta

Phase 2

Myelodysplastic Syndromes

DOX: Docetaxel, oxaliplatin, Capecitabine

Phase 2

Gastric Cancer

Docetaxel, Leucovorin, Fluorouracil, Cisplatin

Phase 2

Gastroesophageal Junction Adenocarcinoma

Emicizumab Injection

Phase 2

Hemophilia A, Acquired

RO7490677

Phase 2

Primary Myelofibrosis

LABA

Phase 2

Asthma

RO5083945

Phase 2

Non-Squamous Non-Small Cell Lung Cancer

PEGPH20

Phase 2

Pancreatic Adenocarcinoma

RO5217790

Phase 2

Cervical Intraepithelial Neoplasia

RO4602522

Phase 2

Alzheimer's Disease

TRO40303

Phase 2

Acute Myocardial Infarctus

preoperative induction chemotherapy in combination with bevacizumab followed by combined radiochemotherapy with capecitabine

Phase 2

Rectal Cancer

Zifibancimig

Phase 2

Macular Degeneration

Tarceva (OSI-774)

Phase 2

Colorectal Cancer

fotemustine

Phase 2

Glioblastoma Multiforme

Doxycline

Phase 2

Non-Small Cell Lung Cancer

capecitabine (Xeloda®)

Phase 2

Breast Cancer

obinutuzumab (RO5072759)

Phase 2

Non-Hodgkin's Lymphoma

Iberdomide

Phase 2

Multiple Myeloma

Standard platinum-based chemotherapy

Phase 2

Non-Small Cell Lung Cancer

bevacizumab (Avastin)

Phase 2

Liver Cancer

Metronidazole Actavis

Phase 2

Non-Squamous Non-Small Cell Lung Cancer

IMM-101

Phase 2

Colorectal Cancer

PTC-Pz

Phase 2

Breast Cancer

gemcitabine, oxaliplatin, capecitabine

Phase 2

Locally Advanced Pancreatic Cancer

ibandronate [Bondronat]

Phase 2

Pain; Bone Neoplasms; Neoplasm Metastasis

Mosunetuzumab (SC)

Phase 2

Follicular Lymphoma

RO4876904

Phase 2

Diabetes Mellitus Type 2

Crenezumab

Phase 2

Alzheimer Disease

setrobuvir

Phase 2

Hepatitis C, Chronic

Forimtamig

Phase 2

Relapsed or Refractory Multiple Myeloma

Induction- PF-06480605 50 mg SC Q4W

Phase 2

Moderate to Severe Ulcerative Colitis

Epidoxorubicin

Phase 2

Breast Cancer

ANA598

Phase 2

HCV Infection

Copegus

Phase 2

Hepatitis C, Chronic

N-acetylcysteine

Phase 2

Idiopathic Pulmonary Fibrosis

OpRegen

Phase 2

Age-Related Macular Degeneration

Pravastatin

Phase 2

Dyslipidemia

RG3421 120mg

Phase 2

Psoriasis

RO7795081

Phase 2

Obesity or Overweight

RO5027838

Phase 2

Diabetes Mellitus Type 2

Pertuzumab, trastuzumab

Phase 2

Esophageal Carcinoma

P38 Inhibitor (4) 150mg

Phase 2

Rheumatoid Arthritis

GDC-4198

Phase 2

Breast Cancer

Enicepatide

Phase 2

Overweight or Obese

Experimental

Phase 2

Diabetic Neuropathy

RG1662

Phase 2

Down Syndrome

Investigator's choice of anti-cancer treatment (except immunotherapy)

Phase 2

Breast Cancer

FOLFIRI + bevacizumab

Phase 2

Colorectal Cancer Metastatic

Basmisanil

Phase 2

Schizophrenia

Trastuzumab emtansine [Kadcyla]

Phase 2

Breast Cancer

Taxane (docetaxel or paclitaxel)

Phase 2

Breast Cancer

RO5190591

Phase 2

Hepatitis C, Chronic

Temozolomide (TMZ)

Phase 2

High Grade Glioma

Oxaliplatine

Phase 2

Metastatic Colorectal Cancer

RAR Gamma

Phase 2

Emphysema

RG7774

Phase 2

Diabetic Retinopathy

Obinutuzumab 25 MG/1 ML Intravenous Solution

Phase 2

Follicular Lymphoma

Samuraciclib

Phase 2

Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer

Trastuzumab deruxtecan

Phase 2

HER2-positive Breast Cancer

Orlistat

Phase 2

Diabetes Mellitus

Perjeta Injectable Product

Phase 2

Breast Neoplasms

Fosamprenavir

Phase 2

HIV Infections

Ibrutinib / Bortezomib / Rituximab

Phase 2

Waldenstrom Macroglobulinemia

Olaparib+Bevacizumab to SCLC patients

Phase 2

Lung Cancer

Atezolizumab [TECENTRIQ]

Phase 2

Lymphoma

Ribociclib

Phase 2

Breast Cancer

NXT007

Phase 2

Hemophilia A

Ocrelizumab Test Formulation

Phase 2

Multiple Sclerosis

Xeloda

Phase 2

Breast Cancer

C.E.R.A.

Phase 2

Anemia

beta-lactam

Phase 2

Soft Tissue Infections

Mosunetuzumab (IV)

Phase 2

B-cell Non-Hodgkin Lymphoma

Chemotherapy ( FOLFIRI regimen, FOLFOX regimen or LV5FU2 regimen)

Phase 2

Colorectal Cancer

Trastuzumab emtansine [Kadcyla] 3.0 mg/kg

Phase 2

Metastatic Breast Cancer

Tumor samples analysis

Phase 2

Triple Negative Breast Cancer

Rituxumab

Phase 2

B-cell Non-Hodgkin Lymphoma

Docetaxel, Cisplatin, 5-FU and Cetuximab

Phase 2

Nasopharyngeal Carcinoma

Didanosine

Phase 2

HIV Infections

Folinic Acid

Phase 2

Rectal Cancer

Polatuzumab vedotin (Liquid)

Phase 2

Lymphoma

Autogene Cevumeran

Phase 2

Muscle-invasive Urothelial Carcinoma

RO7247669 2100 mg

Phase 2

Melanoma

Epothilone D

Phase 2

Breast Cancer

Pertuzumab and Trastuzumab Fixed-Dose Combination for Subcutaneous Administration (PH FDC SC)

Phase 2

HER2-Positive Early Breast Cancer

Interferon alfa-2a

Phase 2

Renal Cell Cancer

Atezolizumab plus Tiraglolumab

Phase 2

Squamous Cell Carcinoma of the Anal Canal

Interleukin 2

Phase 2

HIV Infections

GK Activator (2)

Phase 2

Diabetes Mellitus Type 2

Association atezolizumab + BDB001 + RT

Phase 2

Solid Tumor, Adult

Peg-interféron alpha 2a + ribavirin

Phase 2

Hepatitis

Axitinib

Phase 2

Renal Cell Carcinoma

Mosunetuzumab is a bispecific monoclonal antibody targeting CD20 on B cells and CD3 on T cells, redirecting T cells to eliminate malignant B cells.

Phase 2

Follicular Lymphoma

5-FU, leucovorin, docetaxel, oxaliplatin (FLOT), trastuzumab

Phase 2

Adenocarcinoma of the Gastroesophageal Junction

Atezolizumab (MPDL3280A) [TECENTRIQ]

Phase 2

Lymphoma, Follicular

Immunochemotherapy

Phase 2

Central Nervous System Lymphoma

Bevacizumab 15 mg/kg

Phase 2

Advanced Liver Cancers

Erlotinib + docetaxel

Phase 2

Non Small Cell Lung Cancer

DPP-IV Inhibitor

Phase 2

Diabetes Mellitus Type 2

TCS Cream

Phase 2

Atopic Dermatitis

SPK-8011QQ

Phase 2

Hemophilia A

PEGASYS [peginterferon alfa-2a]

Phase 2

Hepatitis B, Chronic

MSTT1041A

Phase 2

Asthma

RO7017773

Phase 2

Autism Spectrum Disorder (ASD)

RO 205-2349

Phase 2

Diabetes

Danoprevir

Phase 2

Hepatitis C, Chronic

Rituximab and DexaBEAM

Phase 2

Relapsed Non-Hodgkin-Lymphoma

RO5024048

Phase 2

Hepatitis C, Chronic

vismodegib

Phase 2

Basal Cell Carcinoma

RO7247669

Phase 2

Melanoma

enfuvirtide [Fuzeon]

Phase 2

HIV Infections

Tiragolumab and Atezolizumab IV FDC

Phase 2

PD-L1-selected Solid Tumors

RG7314

Phase 2

Autism Spectrum Disorder

Tociliuzumab

Phase 2

COVID-19 Pneumonia

Herceptin+XELOX

Phase 2

Metastatic or Recurrent Gastric Adenocarcinoma

Tocilizumab + Glucocorticoids (GCs)

Phase 2

Giant Cell Arteritis

Olesoxime (TRO19622)

Phase 2

Chemotherapy-Induced Peripheral Neuropathy

RO4998452

Phase 2

Diabetes Mellitus Type 2

Ribavirin [Copegus]

Phase 2

Hepatitis C, Chronic

Atezolizumab 1200 mg in 20 ML Injection

Phase 2

Extensive-stage Small Cell Lung Cancer

RO7126209

Phase 2

Alzheimers Disease

Tominersen

Phase 2

Huntington Disease

Carboplatin/Cisplatin

Phase 2

Nasopharyngeal Cancer

AT-527

Phase 2

COVID-19

Endocrine therapy

Phase 2

HER2-positive Breast Cancer

RO6889450

Phase 2

Schizophrenia, Schizoaffective Disorder

SGN-LIV1A

Phase 2

Metastatic Breast Cancer

FOLFOX induction regimen

Phase 2

Colorectal Cancer

Docetaxel, Capecitabine, Cisplatin, Bevacizumab

Phase 2

Advanced Gastric Cancer

First line chemotherapy

Phase 2

Mantle Cell Lymphoma

fluorouracil (5FU)

Phase 2

Colorectal Cancer

Obinutuzumab Injection [Gazyva]

Phase 2

Stage II Grade 1 Follicular Lymphoma

Diprosone

Phase 2

Metastatic Colorectal Cancer

Atezolizumab 1200 mg/m2

Phase 2

Locally Advanced or Metastatic Urothelial Carcinoma

R-EPOCH and cART

Phase 2

Lymphoma, AIDS Related

RO4917523 0.5 mg

Phase 2

Fragile X Syndrome

Arm A: Atezolizumab and Radiotherapy

Phase 2

Penile Cancer

Mycophenolate Mofetil/Mycophenolic Acid

Phase 2

Lupus Nephritis

RO5313534

Phase 2

Alzheimer's Disease

Pegylated interferon alfa-2a plus nucleos(t)ide(s)

Phase 2

Chronic Hepatitis B

RO5190591 (Danoprevir)

Phase 2

Hepatitis C, Chronic

Balovaptan

Phase 2

Stress Disorders, Post-Traumatic

Carboplatin-based chemotherapy

Phase 2

Non-Small Cell Lung Cancer

Pegylated Interferon (Peginterferon) Alfa-2a

Phase 2

Hepatitis B, Chronic

Glofitamab + Obinutuzumab

Phase 2

Richter Syndrome

Lomvastomig

Phase 2

Advanced or Metastatic Esophageal Squamous Cell Carcinoma

Tenofovir-Emtricitabine

Phase 2

Leukoencephalopathy, Progressive Multifocal

Standard taxane therapy

Phase 2

Breast Cancer

Tocilizumab 20 MG/ML

Phase 2

Sars-CoV2

GC33

Phase 2

Carcinoma, Hepatocellular

Gemcitabine+erlotinib

Phase 2

Metastatic Pancreatic Cancer

RO4905417

Phase 2

Coronary Heart Disease, Graft Occlusion, Vascular

Pertuzumab + trastuzumab

Phase 2

Elderly Metastatic Breast Cancer Population

pralsetinib (BLU-667)

Phase 2

RET-altered Non Small Cell Lung Cancer

SSRI

Phase 2

Obsessive-Compulsive Disorder

P38 Inhibitor (4)

Phase 2

Rheumatoid Arthritis

Ceftriaxone

Phase 2

Pneumonia, Bacterial

danoprevir + ritonavir

Phase 2

Hepatitis C, Chronic

eloxatin

Phase 2

Colorectal Cancer

PEG-IFN alfa-2a, Tenofovir

Phase 2

Hepatitis D

Bendamustine, Rituximab, Lenalidomide

Phase 2

Chronic Lymphocytic Leukemia

Nucleos(t)ide (NUC)

Phase 2

Hepatitis B, Chronic

Atezolizumab Injection [Tecentriq]

Phase 2

Bladder Cancer

MPDL3280A

Phase 2

Non-small Cell Lung Cancer

Peg-interferon alpha 2a (drug)

Phase 2

Hepatitis C, Chronic

Inhaled corticposteroids (ICS)

Phase 2

Asthma

rituximab (anti-CD20)

Phase 2

Sjogren's Syndrome

Ipatasertib 300mg

Phase 2

Metastatic Breast Cancer

Myocet

Phase 2

Breast Cancer

Optimized Background ARVs

Phase 2

HIV Infections

Abacavir sulfate

Phase 2

HIV Infections

bevacizumab and trabectedin

Phase 2

Ovarian Epithelial Cancer Recurrent

RO5459072

Phase 2

Sjogren's Syndrome

Alogabat

Phase 2

Angelman Syndrome

89Zr-Df-IAB22M2C

Phase 2

Non-Hodgkins Lymphoma

GA101

Phase 2

Chronic Lymphocytic Leucemia

RO5185426

Phase 2

Malignant Melanoma

Mosunetuzumab Intravenous (IV)

Phase 2

Diffuse Large B-cell Lymphoma

Ribavirine

Phase 2

Chronic Hepatitis C

RO4917523

Phase 2

Fragile X Syndrome

RO7269162

Phase 2

Alzheimer's Disease

Erlotinib, escalating dose

Phase 2

Pancreatic Cancer

L-Leucovorin

Phase 2

Metastatic Colorectal Cancer

Taspoglutide 20mg

Phase 2

Diabetes Mellitus Type 2

RO6958688

Phase 2

Carcinoma, Non-Small-Cell Lung

Atezolizumab (MPDL3280A), an engineered anti-programmed death-ligand 1 (PD-L1) antibody

Phase 2

Breast Neoplasms

RO4929097

Phase 2

Non-Squamous Non-Small Cell Lung Cancer

Market-Implied Move
Regulatory Approvals

Frequently asked questions

What is in Roche Holding AG's drug pipeline?

CatalystAlert tracks 497 drug candidates in Roche Holding AG's (RHHBY) pipeline across Phase 3, Phase 2. Its lead program is RO7239361 (Phase 3). Each drug's phase, indication and upcoming catalysts are listed on this page.

When is Roche Holding AG's next FDA catalyst?

Roche Holding AG's (RHHBY) next tracked catalyst is a Phase 2 expected August 26, 2026. See the catalyst timeline on this page for the full schedule of PDUFA dates, trial readouts and FDA events.

How do I track RHHBY biotech catalysts?

Add RHHBY to your CatalystAlert watchlist for alerts ahead of each catalyst, and follow Roche Holding AG's live catalyst calendar, drug pipeline and clinical-trial timeline on this page — sourced from ClinicalTrials.gov, FDA and SEC filings.

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Data is aggregated from public sources (FDA, SEC, ClinicalTrials.gov). While we strive for accuracy, information may be incomplete, delayed, or contain errors. Terms apply