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February 18, 2026 · Phase 3 readout

PFE Phase 3 readout: a positive outcome, -1.9%

On February 18, 2026, talazoparib plus enzalutamide — PFIZER (Prostate Cancer) reached its Phase 3 readout. The result was a positive outcome, and the stock moved -1.9% in the window around the event. It had already run +9.1% in the 30 days into the catalyst — the kind of pre-event run-up that often precedes binary readouts.

The move

$27.37
1d before
$27.37
Event day
$26.86
1d after
$27.06
5d after

Pre-catalyst setup

+9.1%
30-day run-up
2407%
30-day volatility
0.6×
volume spike