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BioSpace
Original article

Roche cuts muscle-sparing obesity drug after mid-stage disappointment

Phase 2negativeemugrobartNegative
AI Analysis

Summary

Roche discontinued development of emugrobart, an anti-myostatin obesity drug, after an interim mid-stage analysis indicated it was unlikely to produce meaningful weight loss, returning the asset rights to subsidiary Chugai Pharmaceutical.

Clinical Trial Data

Phase

2

Primary Endpoint

Not Met

Outcome Details

interim mid-stage analysis showed anti-myostatin therapy unlikely to elicit meaningful weight loss

Importance:7/10
Sentiment:
-0.85
obesityanti-myostatinclinical_failureasset_returnmid-stage
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Published by BioSpace on September 29, 2026 2:13 PM

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