Cell (In Press)Original article
A microbiome-bile acid axis mediates protection from chronic liver disease in females
isoUDCANeutral
AI Analysis
Summary
A Cell study reports that isoUDCA, a female-enriched bile acid produced by an estrogen-favored gut bacterial consortium, alleviates chronic liver injury by promoting hepatic cholesterol handling and bile acid metabolism via SREBP2-STARD4-CYP7B1 signaling.
Outcome Details
Preclinical academic research published in Cell; no clinical or regulatory milestone.
Importance:2/10
Sentiment:
0.20
preclinicalacademic researchmicrobiomebile acidsliver diseasesex differencesestrogen
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Published by Cell (In Press) on October 19, 2026 12:00 AM