Clinical Trials ArenaOriginal article
Argenx cans Phase III Vyvgart Sjögren’s study on predicted efficacy fail
Phase 3negativeVyvgartVyvgart HytruloNegative
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Summary
Argenx has terminated its Phase III trial of Vyvgart in Sjögren's syndrome due to predicted efficacy failure. The company is pursuing further label expansion opportunities for Vyvgart Hytrulo in other immunological indications.
Clinical Trial Data
Phase
Phase 3
Primary Endpoint
Not Met
Outcome Details
Phase III Vyvgart Sjögren's study discontinued due to predicted efficacy failure
Importance:7/10
Sentiment:
-0.80
Phase 3 failurestudy discontinuationSjögren's syndromeVyvgartlabel expansion
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Published by Clinical Trials Arena on October 8, 2026 10:45 AM
