Endpoints NewsOriginal article
Roche ends work on tominersen after decade of trials, as well as early-stage Huntington’s asset
Phase 2negativetominersenNegative
AI Analysis
Summary
Roche has discontinued tominersen for Huntington's disease after more than a decade of development following negative Phase 2 trial results showing no efficacy advantage over placebo. The company is also discontinuing an early-stage Huntington's asset as part of this strategic decision.
Clinical Trial Data
Phase
Phase 2
Primary Endpoint
Not Met
Outcome Details
tominersen did no better than placebo in Phase 2 trial
Importance:7/10
Sentiment:
-0.95
program_discontinuationhuntingtons_diseasephase_2_failurefailed_trial
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Published by Endpoints News on July 9, 2026 6:17 PM
