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AstraZeneca PLC

AZN
$273.62B
Mega Cap
NASDAQPharmaceutical PreparationsPharmaceutical🇺🇸EuropeCAMBRIDGE89.9K employees

AstraZeneca plc (/ˌæstrəˈzɛnəkə/) (AZ) is a Swedish–British multinational pharmaceutical and biotechnology company with its headquarters at the Cambridge Biomedical Campus in Cambridge, England. It has a portfolio of products for major diseases in areas including oncology, cardiovascular, gastrointestinal, infection, neuroscience, respiratory, and inflammation.

Website

Drugs in Pipeline

416

Phase 3 Programs

211

Upcoming Catalysts

28

Next Catalyst

Nov 2026

Market Overview

Stock performance and key metrics

AZN News
Catalyst Timeline

33 upcoming, 8 past

Phase 2Next
Positive

AZD2936 Phase 2 Est. Readout

August 2026~AZD2936212

Primary completion for AZD2936 trial (NCT04995523) in Non-Small-Cell Lung Carcinoma

VISTA Phase IIb: 11.8% weight loss at 36 weeks in adults with obesity/overweight. SOLSTICE Phase IIb: 1.9% HbA1c reduction at 26 weeks in adults with type 2 diabetes

Source

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How AZN's past catalysts played out

Drug Pipeline

Baxdrostat and dapagliflozin

Phase 3

Heart Failure

Benralizumab Arm B

Phase 3

Moderate to Very Severe Chronic Obstructive Pulmonary Disease

D961H capsule 10mg

Phase 3

Reflux Esophagitis

ZD9393 (Zoladex) 10.8 mg

Phase 3

Breast Cancer

Olaparib

Phase 3

Breast Cancer Metastatic

ABT-335 and rosuvastatin calcium

Phase 3

Hypercholesterolemia

Formoterol Turbuhaler® 4.5mg

Phase 3

Chronic Obstructive Pulmonary Disease

Osimertinib (AZD9291) pemetrexed cisplatin or carboplatin

Phase 3

Non-small Cell Lung Cancer

cyclophosphamide, bortezomib, and dexamethasone (CyBorD) regimen

Phase 3

AL Amyloidosis

AZD9291

Phase 3

Advanced Non Small Cell Lung Cancer

Baxdrostat/dapagliflozin

Phase 3

Chronic Kidney Disease and Hypertension

Saruparib

Phase 3

Prostate Cancer

Sulphonylurea

Phase 3

Type 2 Diabetes

Datopotamab Deruxtecan

Phase 3

Non-small Cell Lung Cancer

Saxagliptin, Onglyza

Phase 3

Type 2 Diabetes Mellitus

Theophylline

Phase 3

Asthma

Anastrazole (Arimidex)

Phase 3

Breast Cancer

Acetylsalicylic acid ASA

Phase 3

Acute Coronary Syndrome

Sodium Zirconium Cyclosilicate (ZS) 10g

Phase 3

Hyperkalemia

Oleclumab

Phase 3

Non-Small Cell Lung Cancer

Sodium Zirconium Cyclosilicate (ZS)

Phase 3

Hyperkalemia

Gefitinib

Phase 3

Non-Small Cell Lung Cancer

Tremelimumab

Phase 3

Advanced Hepatocellular Carcinoma

Aclidinium Bromide/Formoterol Fumarate

Phase 3

Chronic Obstructive Pulmonary Disease

Pramlintide acetate

Phase 3

Diabetes Mellitus, Type 1

Tozorakimab

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Medi-546

Phase 3

Systemic Lupus Erythematosus

AZD9291 Dosing

Phase 3

Lung Cancer

Ciclesonide nasal spray

Phase 3

Hay Fever

AZD4831

Phase 3

Heart Failure With Preserved Ejection Fraction

Seasonal influenza virus vaccine

Phase 3

Asthma

Rosuvastatin 20mg

Phase 3

Homozygous Familial Hypercholesterolemia (HoFH)

candsartan cilexetil

Phase 3

Hypertension

Gemcitabine/Cisplatin

Phase 3

Biliary Tract Cancer

Saxagliptin 5 mg

Phase 3

Type 2 Diabetes Mellitus

Nexium 20mg

Phase 3

Erosive Esophagitis

Eplontersen

Phase 3

Transthyretin Amyloid Cardiomyopathy

omefas

Phase 3

Severe Hypertriglyceridemia

pexelizumab

Phase 3

Cardio-pulmonary Bypass

Benralizumab (Medi-563)

Phase 3

Asthma

Lithium carbonate

Phase 3

Acute Bipolar Depression

Metformin XR

Phase 3

Type 2 Diabetes

Dato-DXd

Phase 3

Breast Cancer

SSRI/Clomipramine

Phase 3

Obsessive Compulsive Disorder

MEDI4736 + Tremelimumab

Phase 3

Recurrent or Metastatic PD-L1-positive or -Negative Squamous Cell Carcinoma of the Head and Neck SCCHN

Escitalopram oxylate

Phase 3

Generalized Anxiety Disorder

Mepolizumab

Phase 3

Eosinophilic Granulomatous Vasculitis

Dapagliflozin 10 mg

Phase 3

Diabetes Mellitus, Non-Insulin-Dependent

Symbicort

Phase 3

COPD Patients

Benralizumab

Phase 3

Asthma

exenatide

Phase 3

Type 2 Diabetes Mellitus

Aclidinium Bromide / Formoterol Fumarate

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Aclidinium bromide

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

MEDI8897

Phase 3

Respiratory Syncytial Virus Infections

Saxagliptin, 5 mg + insulin

Phase 3

Type 2 Diabetes

Exenatide (AC2993)

Phase 3

Diabetes Mellitus, Type 2

HFO-1234ze(E)

Phase 3

Mucociliary Clearance

Osimertinib

Phase 3

Lung Cancer

Tiotropium

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Terbutaline sulphate

Phase 3

Asthma

ALXN2060

Phase 3

Symptomatic Transthyretin Amyloid Cardiomyopathy

Selumetinib

Phase 3

Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIb - IV

Metformin (blinded)

Phase 3

Type 2 Diabetes

Ciclesonide

Phase 3

Perennial Allergic Rhinitis

Aclidinium bromide 400 μg/Formoterol Fumarate 12 μg (AB/FF 400/12 μg)

Phase 3

Chronic Obstructive Pulmonary Disease

Experimental: Tezepelumab

Phase 3

Chronic Rhinosinusitis With Nasal Polyps

Baxdrostat

Phase 3

Resistant Hypertension

TC-5214

Phase 3

Major Depressive Disorder

Tezepelumab

Phase 3

Moderate to Severe Asthma

AZD9833

Phase 3

ER-Positive HER2-Negative Breast Cancer

Benralizumab Arm A

Phase 3

Moderate to Very Severe Chronic Obstructive Pulmonary Disease

formoterol

Phase 3

Asthma

10mg Rosuvastatin

Phase 3

Renal Failure

Saxagliptin

Phase 3

Type 2 Diabetes

Gefitinib (Iressa)

Phase 3

Cancer

MEDI4736

Phase 3

Squamous Cell Carcinoma of the Head and Neck

Candesartan cilexetil

Phase 3

Hypertension

BCG

Phase 3

Non-Muscle- Invasive Bladder Cancer

Durvalumab (MEDI4736)

Phase 3

Non-muscle-invasive Bladder Cancer

exenatide, long acting release

Phase 3

Type 2 Diabetes Mellitus

Rosuvastatin (Crestor)

Phase 3

Hypercholesterolemia

BGF MDI 320/28.8/9.6 μg

Phase 3

Asthma

Tezepelumab (APFS)

Phase 3

Asthma

BGF MDI HFO 320/14.4/9.6 μg

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Datopotamab deruxtecan (Dato-DXd)

Phase 3

Non-small Cell Lung Cancer (NSCLC)

Saxagliptin 5mg

Phase 3

Type 2 Diabetes Mellitus

exenatide once weekly

Phase 3

Type 2 Diabetes Mellitus

Gefitinib, raltitrexed

Phase 3

Colorectal Cancer

Zibotentan/Dapagliflozin

Phase 3

Chronic Kidney Disease With High Proteinuria

ABT-335 plus rosuvastatin

Phase 3

Dyslipidemia

Acetylsalicylic acid (ASA)

Phase 3

Acute Ischaemic Stroke

ATACAND

Phase 3

Hypertension

AC2993

Phase 3

Diabetes Mellitus, Type 2

Symbicort Turbuhaler

Phase 3

Bronchial Asthma

rosiglitazone

Phase 3

Diabetes Mellitus, Type 2

Durvalumab plus chemotherapy

Phase 3

Small Cell Lung Carcinoma Extensive Disease

AZD5156 (Parent study Sentinel Safety Cohort)

Phase 3

COVID-19, SARS-CoV-2

Sodium Zirconium Cyclosilicate (SZC) Reduced Dose Level

Phase 3

Hyperkalaemia

5-fluorouracil

Phase 3

Colorectal Cancer

Saxagliptin 2.5 mg

Phase 3

Type 2 Diabetes Mellitus, CKD and Albuminuria

Saxagliptin + Metformin

Phase 3

Diabetes Mellitus, Type 2

Nirsevimab

Phase 3

Respiratory Syncytial Virus Infections

D9421-C capsule 3 mg

Phase 3

Crohn's Disease

Pulmicort Turbuhaler

Phase 3

Asthma

Camizestrant

Phase 3

Advanced Breast Cancer

Cimetidine

Phase 3

Stress Ulcer Prophylaxis

Ticagrelor 60 mg

Phase 3

Diabetes Mellitus, Type 2

Gemcitabine monotherapy

Phase 3

Biliary Tract Cancer

FLOT chemotherapy

Phase 3

Gastrointestinal Neoplasms

Rilvegostomig

Phase 3

Hepatocellular Carcinoma

Daptomycin

Phase 3

Skin Diseases

5-fluorouracil ( in FOLFOX)

Phase 3

Colorectal Cancer

Epanova

Phase 3

Hypertriglyceridemia

MEDI4736 (durvalumab)

Phase 3

Non - Small Cell Lung Cancer NSCLC

Intralipid

Phase 3

Sedation to be Moderate for a Diagnostic Gastrointestinal Endoscopy and Gastrointestinal Endoscopic Polypectomy

exenatide twice daily (BID)

Phase 3

Type 2 Diabetes Mellitus

BGF MDI HFO 320/14.4/9.6μg

Phase 3

COPD (Chronic Obstructive Pulmonary Disease)

Thiazolidinedione (Pioglitazone)

Phase 3

Type 2 Diabetes

Roxadustat

Phase 3

Anemia

Cisplatin + Gemcitabine

Phase 3

Unresectable Locally Advanced Urothelial Cancer

ABT-143

Phase 3

Dyslipidemia, Hypercholesterolemia, Hypertriglyceridemia

ZD4054

Phase 3

Prostate Cancer

Capivasertib

Phase 3

Triple Negative Breast Neoplasms

corn oil control

Phase 3

Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)

Dapagliflozin 5 mg

Phase 3

Type 1 Diabetes Mellitus

Conventional Asthma Therapy

Phase 3

Asthma

Pemetrexed/Carboplatin

Phase 3

Non-Small Cell Lung Cancer

pravastatin

Phase 3

Hyperlipoproteinemia Type III

candesartan cilexetil (Atacand)

Phase 3

Hypertension

AZD1222

Phase 3

COVID-19

Durvalumab + SoC chemotherapy

Phase 3

Carcinoma, Non-Small-Cell Lung

ZD1839 (Gefitinib)

Phase 3

Carcinoma

Amitriptyline

Phase 3

Major Depressive Disorder

faslodex 500mg

Phase 3

Hormone Receptor Positive Breast Cancer

Single agent chemotherapy

Phase 3

Relapsed Ovarian Cancer, BRCA Mutation, Platinum Sensitivity

Carboplatin+Paclitaxel

Phase 3

Advanced Ovarian Cancer

Olaparib 300mg tablets

Phase 3

Relapsed Ovarian Cancer

Active Comparator: Olaparib tablets

Phase 3

Epithelial Ovarian Cancer

NKTR-118

Phase 3

Opioid-Induced Constipation (OIC)

Osimertinib 80mg/40mg

Phase 3

Non Small Cell Lung Cancer (Stage III)

Zirconium Cyclosilicate

Phase 3

Hyperkalemia

Cediranib

Phase 3

Metastatic Colorectal Cancer

Metformin IR

Phase 3

Type 2 Diabetes

Lomustine Chemotherapy

Phase 3

Recurrent Glioblastoma

AZD2816

Phase 3

COVID-19

Rosuvastatin Dose 1

Phase 3

Dyslipidaemia

Roflumilast

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Aclidinium Bromide 200 µg

Phase 3

Chronic Obstructive Pulmonary Disease

Symbicort pMDI

Phase 3

Asthma

Acalabrutinib

Phase 3

Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Seroquel SR

Phase 3

Schizophrenia

Anifrolumab

Phase 3

Lupus Nephritis

Savolitinib

Phase 3

Carcinoma

Aclidinium bromide 200 μg bid

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Exantide with Dapagliflozin

Phase 3

Diabetes Mellitus

Epoetin alfa

Phase 3

Anemia

Sodium Zirconium Cyclosilicate

Phase 3

Hyperkalemia

AZD5335

Phase 3

Epithelial Ovarian Cancer

divalproex

Phase 3

Bipolar I Disorder

Rosuvastatin calcium

Phase 3

Hypercholesteremia

tralokinumab

Phase 3

Ulcerative Colitis

Zolmitriptan

Phase 3

Migraine

MEDI3250

Phase 3

Healthy Japanese Children Age 7 Years Through 18 Years

AZD0780

Phase 3

Heterozygous Familial Hypercholesterolaemia

exenatide/insulin glargine

Phase 3

Type 2 Diabetes Mellitus

Candesartan

Phase 3

Congestive Heart Failure

lithium

Phase 3

Bipolar I Disorder

Exenatide once weekly suspension

Phase 3

Diabetes Mellitus, Type 2

budesonode bid + terbutaline 'as needed'

Phase 3

Asthma

insulin lispro

Phase 3

Type 2 Diabetes Mellitus

Metformin immediate release (IR)

Phase 3

Type 2 Diabetes

Saxagliptin plus metformin IR

Phase 3

Type 2 Diabetes Mellitus

Symbicort TBH - Turbuhaler

Phase 3

Asthma

Olive oil, 4g

Phase 3

Hypertriglyceridemia

glipizide

Phase 3

Type 2 Diabetes

Terbutaline Turbuhaler®

Phase 3

Asthma

Linaclotide

Phase 3

Irritable Bowel Syndrome With Constipation (IBS-C)

(Osimertinib cohort, single-arm, open-label separate cohort)

Phase 3

Carcinoma, Non-Small-Cell Lung

BFF MDI 320/9.6 μg

Phase 3

Asthma

NXY-059

Phase 3

Intracerebral Hemorrhage

CRESTOR

Phase 3

Heart Failure

Pertuzumab

Phase 3

Breast Neoplasms

Seroquel Sustained Release (SR)

Phase 3

Schizophrenic Disorder

cisplatin + fluorouracil

Phase 3

Esophageal Squamous Cell Carcinoma

Ravulizumab

Phase 3

Thrombotic Microangiopathy

CAEL-101

Phase 3

AL Amyloidosis

AZD7442

Phase 3

COVID-19

Sebelipase alfa (SBC-102)

Phase 3

Lysosomal Acid Lipase Deficiency

Eculizumab

Phase 3

Atypical Hemolytic Uremic Syndrome

Surovatamig

Phase 3

B-cell Non-Hodgkin Lymphoma

Ticagrelor

Phase 3

Acute Coronary Syndrome

Volrustomig

Phase 3

Non-small Cell Lung Cancer

Eculizumab (Soliris®)

Phase 3

Shiga-like Toxin-producing Escherichia Coli

Andexanet

Phase 3

Bleeding

Epanova® (omega-3 carboxylic acids)

Phase 3

Diabetes Mellitus, Type 2

Casdatifan

Phase 3

Advanced Clear Cell Renal Cell Carcinoma

ALXN1850

Phase 3

Hypophosphatasia

ALXN2220

Phase 3

Transthyretin Amyloid Cardiomyopathy

sebelipase alfa

Phase 3

Cholesterol Ester Storage Disease (CESD)

C5 Inhibitor

Phase 3

Paroxysmal Nocturnal Hemoglobinuria

Danicopan

Phase 3

C3 Glomerulonephritis

asfotase alfa

Phase 3

Hypophosphatasia

pexelizumab in conjunction with CABG

Phase 3

Coronary Artery Disease

Tozorakimab Dose Regimen 1

Phase 3

Chronic Obstructive Pulmonary Disease

Sonesitatug vedotin

Phase 3

Gastric Cancer

AZD1152

Phase 3

Acute Myeloid Leukemia

Chemotherapy

Phase 3

Anticancer Treatment

Saruparib (AZD5305)

Phase 3

Ovarian Cancer

exenatide twice daily

Phase 3

Type 2 Diabetes Mellitus

Ciclesonide nasal

Phase 3

Rhinitis, Allergic, Perennial

fostamatinib

Phase 3

Rheumatoid Arthritis

AC2993 (exenatide)

Phase 2

Diabetes Mellitus

AZD6234

Phase 2

Obesity/Overweight

MEDI6570

Phase 2

Coronary Heart Disease (CHD)

Tremelimumab monotherapy

Phase 2

Urothelial Bladder Cancer

B - Exenatide 10 mcg twice daily

Phase 2

Diabetes Mellitus, Type 2

ZD1839

Phase 2

Mesothelioma

Exenatide LAR

Phase 2

Type 2 Diabetes Mellitus

plevitrexed

Phase 2

Fallopian Tube Cancer

Ticagrelor Dose 1a + Dose 2a

Phase 2

Investigation of Platelet Aggregation in Paediatric Patients With Sickle Cell Disease

AZD1981

Phase 2

Asthma

AZD0865

Phase 2

GERD Without Erosive Esophagitis

SBC-103

Phase 2

Mucopolysaccharidosis IIIB

Atuliflapon

Phase 2

Asthma

AZD3470

Phase 2

Lymphoma

AZD9773

Phase 2

Severe Sepsis

AZD7789

Phase 2

Carcinoma, Non-Small-Cell Lung

AZD1940

Phase 2

Pain

Aclidinium 400 μg / Formoterol 12 μg

Phase 2

Chronic Obstructive Pulmonary Disease

AZD9793 Intravenous (IV) monotherapy

Phase 2

Hepatocellular Carcinoma

Anastrazole

Phase 2

Breast Cancer

Cotadutide

Phase 2

Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis

Sovaprevir

Phase 2

Hepatitis C, Chronic

AZD2927

Phase 2

Arrhythmia

cediranib and olaparib

Phase 2

Recurrent Platinum Resistant Ovarian Cancer

MEDI3506

Phase 2

Atopic Dermatitis

AZD0022

Phase 2

Advanced Solid Tumours

lesogaberan (AZD3355)

Phase 2

Gastroesophageal Reflux Disease

pramlintide acetate 360 mcg

Phase 2

Overweight

AZD2171

Phase 2

Metastatic Colorectal Cancer

AZD5363 when combined with weekly paclitaxel.

Phase 2

Advanced or Metastatic Breast Cancer

ACH-0144471

Phase 2

Paroxysmal Nocturnal Hemoglobinuria

AZD7648

Phase 2

Advanced Malignancies

ACH-0141625 (Sovaprevir)

Phase 2

Hepatitis C

Tarperprumig

Phase 2

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

CP-675,206

Phase 2

Malignant Melanoma

AZD1305

Phase 2

Atrial Fibrillation

GC012F (AZD0120)

Phase 2

Relapsed/ Refractory Multiple Myeloma

AZD8848

Phase 2

Allergic Asthma

Tiotropium 18 μg once-daily

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

AZD9056

Phase 2

Rheumatoid Arthritis

Casodex

Phase 2

Gynaecomastia

Lenvatinib

Phase 2

Hepatocellular Carcinoma

AZD7594 DPI 55μg/50μg.

Phase 2

Asthma

AZD5423

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

Iressa

Phase 2

Locally Advanced Prostate Cancer

AZD9164

Phase 2

Chronic Obstructive Pulmonary Disease

Bis-Choline Tetrathiomolybdate

Phase 2

Wilson Disease

Ticagrelor Tablets

Phase 2

Coronary Artery Disease

Formoterol Fumarate in the Pressair DPI, Low Dose

Phase 2

Asthma

Bertilimumab

Phase 2

Pemphigoid, Bullous

Sebelipase alfa 0.35 mg/kg

Phase 2

Cholesterol Ester Storage Disease(CESD)

KU-0059436 (AZD2281)(PARP inhibitor)

Phase 2

Ovarian Neoplasm

AZD2936

Phase 2

Non-Small-Cell Lung Carcinoma

AZD5492

Phase 2

B-cell Malignancies

Part A:AZD8233

Phase 2

Dyslipidemia

AZD2281

Phase 2

Ovarian Neoplasms

80/2.25 μg Symbicort pMDI

Phase 2

Asthma

AZD5851

Phase 2

Hepatocellular Carcinoma

sibutramine

Phase 2

Overweight

Sodium Zirconium Cyclosilicate(ZS)

Phase 2

Hyperkalemia

Anastrozole and goserelin

Phase 2

Breast Cancer

AZD8931

Phase 2

Neoplasms

Gefitinib, Cisplatin and Radiotherapy

Phase 2

Cancer of Head and Neck

AZD4017

Phase 2

Raised Intraocular Pressure

AZD2423

Phase 2

Chronic Obstructive Pulmonary Disease

Ceralasertib

Phase 2

Advanced Solid Tumours

AZD4818

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

Interferon beta-1a Nebuliser solution 48 μg/mL

Phase 2

Asthma

AC2993 2.5 mcg

Phase 2

Diabetes Mellitus, Non-Insulin-Dependent

AZD3480

Phase 2

ADHD

Biological: AZD3152

Phase 2

COVID-19, SARS-CoV-2

VKA INR 2-3

Phase 2

Persistent or Permanent Nonvalvular Atrial Fibrillation

AZD4360

Phase 2

Gastric Cancer

FOLFIRI (Fluorouracil (5-FU), leucovorin, irinotecan)

Phase 2

Metastatic Colorectal Cancer

Selumetinib 75 mg

Phase 2

Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIb - IV

AZD4117

Phase 2

Influenza A

Aclidinium bromide 100 μg bid

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

AC2592

Phase 2

Congestive Heart Failure

AZD7325

Phase 2

Anxiety Disorders

AZD5462

Phase 2

Chronic Heart Failure

CIN-107

Phase 2

Uncontrolled Hypertension

AZD8630

Phase 2

Asthma

AZD2389

Phase 2

Liver Fibrosis

ER tablet 25 mg AZD3241

Phase 2

Parkinson's Disease

Aclidinium/formoterol 400/12μg

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

Gefitinib, radiotherapy

Phase 2

Non-Metastatic Prostate Cancer

Cotadutide 100 micrograms

Phase 2

Type 2 Diabetes Mellitus

MEDI4736 monotherapy

Phase 2

Metastatic Pancreatic Ductal Adenocarcinoma

AZD9773 (CytoFab)

Phase 2

Severe Sepsis

AZD8421

Phase 2

ER+ HER2- Advanced Breast Cancer

Durvalumab and Tremelimumab

Phase 2

Platinum Refractory Extensive-Stage Small Cell Lung Carcinoma

Cediranib 30 - 90 mg

Phase 2

Cancer

ACH-126,443

Phase 2

Hepatitis B, Chronic

ALXN2350

Phase 2

BAG3 Mutation Associated Dilated Cardiomyopathy

Aclidinium 200 μg / formoterol 12 μg

Phase 2

Chronic Obstructive Pulmonary Disease

ALXN2420

Phase 2

Acromegaly

ALXN1210

Phase 2

PNH

AZD3427

Phase 2

Pulmonary Hypertension (World Health Organization Group 2)

Mitiperstat (AZD4831)

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

AZD7798

Phase 2

Crohn's Disease

AZD6765

Phase 2

Treatment Resistant Major Depressive Disorder

Pramlintide and Metreleptin

Phase 2

Obesity

Omega-3 carboxylic acid

Phase 2

Non-alcoholic Fatty Liver Disease (NAFLD

terbutaline

Phase 2

Exercise Induced Asthma

Gefitinib and capecitabine

Phase 2

Colorectal Cancer

BMS-512148

Phase 2

Diabetes Mellitus, Type 2

Monalizumab

Phase 2

Non-small Cell Lung Cancer

AZD1656

Phase 2

Type 2 Diabetes Mellitus

Anastrozole (ARIMIDEX™)

Phase 2

Gynecomastia

AB248

Phase 2

Advanced or Metastatic Non-small Cell Lung Cancer

AZD2066

Phase 2

Reflux Episodes

Fluorouracil (5-FU)

Phase 2

Gastric Cancer

Goserelin acetate

Phase 2

Advanced Breast Cancer

SoC: cyclophosphamide, bortezomib, and Dexamethasone (CyBorD)

Phase 2

AL Amyloidosis

AZD3241

Phase 2

Multiple System Atrophy, MSA

AS MDI 90 μg

Phase 2

Asthma

AZD2693

Phase 2

Nonalcoholic Steatohepatitis

AZD8233

Phase 2

Hyperlipidaemia

AZD3241 300 mg BID

Phase 2

Parkinson's Disease

AZD6750

Phase 2

Melanoma

D9421-C, 9mg

Phase 2

Crohn's Disease

AS MDI

Phase 2

Asthma

Adavosertib

Phase 2

Ovarian, Fallopian Tube, Peritoneal Cancer, P53 Mutation

AZP-3601

Phase 2

Chronic Hypoparathyroidism

AZD4901 (oral)

Phase 2

Polycystic Ovary Syndrome (PCOS), Female Endocrine Disorder

AZD 8529

Phase 2

Schizophrenia

MEDI7352

Phase 2

Painful Osteoarthritis of the Knee

AZD9567

Phase 2

Diabetes Mellitus, Type 2

AZD9668

Phase 2

Chronic Obstructive Pulmonary Disease

AZD6621

Phase 2

Prostate Cancer

800 μg AZD7594 once daily

Phase 2

Asthma

AZD8601

Phase 2

Heart Failure

5-flourouracil

Phase 2

Squamous Cell Cancer

MEDI-545

Phase 2

Systemic Lupus Erythematosus

AZD4635

Phase 2

Prostate Cancer

AZD6094

Phase 2

Papillary Renal Cell Cancer

AZD0120

Phase 2

Lupus Erythematosus, Systemic

AZD3199

Phase 2

COPD

AC2307

Phase 2

Obesity

AZD5213

Phase 2

Mild Cognitive Impairment

5-Fluorouracil (5-FU)

Phase 2

Gastroesophageal Adenocarcinoma

Administration of ceralasertib

Phase 2

Adv Solid Malig - H&N SCC, ATM Pro / Def NSCLC, Gastric, Breast and Ovarian Cancer

Danvatirsen

Phase 2

Non-Small Cell Lung Cancer

AZD5718

Phase 2

Coronary Artery Disease

MEDI2070

Phase 2

Crohn's Disease

Verinurad 9 mg+Febuxostat 80 mg

Phase 2

Hyperuricemia

AZD3355

Phase 2

GERD

ICI35,868 (propofol)

Phase 2

Gastrointestinal Endoscopy

exenatide (LY2148568)

Phase 2

Type 2 Diabetes Mellitus

AZD4604

Phase 2

Asthma

0.5% Roflumilast Cream

Phase 2

Atopic Dermatitis

AZD6244

Phase 2

Non Small Cell Lung Cancer

Verinurad

Phase 2

Chronic Kidney Disease

Ciclesonide/Formoterol Combination

Phase 2

Asthma

Olaparib Continuous (28-Day cycle) 300 mg BD.

Phase 2

Metastatic Triple Negative Breast Cancer

metreleptin

Phase 2

Overweight

RDEA3170

Phase 2

Gout and Hyperuricemia

AZD9550

Phase 2

Overweight and Obesity

AZD8871

Phase 2

Chronic Obstructive Pulmonary Disease

AZD2115

Phase 2

COPD

Epanova (4 g) and Lovaza (4 g)

Phase 2

Severe Hypertriglyceridemia

AZD7009, no generic name available

Phase 2

Atrial Fibrillation

600 mg AZD7442 IV

Phase 2

Coronavirus Disease 2019 (COVID-19)

AZD5069 50mg

Phase 2

Scientific Terminology Chronic Obstructive Pulmonary Disease (COPD)

AZD2327

Phase 2

Anxious Major Depressive Disorder

Cerdulatinib

Phase 2

Follicular Lymphoma (FL/Indolent NHL)

AZD9977

Phase 2

Heart Failure

ZD4054 10 mg

Phase 2

Prostatic Neoplasms

AZD0837

Phase 2

Nonvalvular Atrial Fibrillation

ALXN1920

Phase 2

Primary Membranous Nephropathy

AZD0901

Phase 2

Gastric Cancer

CP-675,206 and leuprolide acetate and bicalutamide

Phase 2

Prostatic Neoplasms

AZD1446

Phase 2

Adult ADHD

AZD0486

Phase 2

Chronic Lymphocytic Leukaemia

AZD9150

Phase 2

Advanced Solid Tumors & Metastatic Squamous Cell Carcinoma of the Head and Neck

AZD0171

Phase 2

Locally Advanced or Metastatic Solid Tumours

AZD8205

Phase 2

Breast Cancer

Leucovorin LV

Phase 2

Endometrial Cancer

gefitinib and fulvestrant

Phase 2

Breast Cancer

Osimertinib + Savolitinib

Phase 2

Non-Small Cell Lung Cancer

Salmeterol

Phase 2

Chronic Obstructive Pulmonary Disease

Lamivudine

Phase 2

HIV Infections

AZD4512

Phase 2

B-cell Non-Hodgkin Lymphoma

AZD1163

Phase 2

Rheumatoid Arthritis

Neoadjuvant Olaparib monotherapy group

Phase 2

Breast Cancer

AZD0530

Phase 2

Breast Cancer

AZD5305

Phase 2

Ovarian Cancer

AZD7760

Phase 2

Staphylococcus Aureus

AZD4573

Phase 2

Advanced Haematological Malignancies

AZD2624

Phase 2

Schizophrenia

Elvucitabine

Phase 2

Human Immunodeficiency Virus (HIV)-1 Infection

AZD9829

Phase 2

Hematological Malignancies

AZD8871 100 µg

Phase 2

Chronic Obstructive Pulmonary Disease COPD

MEDI0382 low dose

Phase 2

Diabetes Mellitus, Type 2

ALXN2030

Phase 2

Antibody-Mediated Rejection

AZD0754

Phase 2

Metastatic Prostate Cancer

ALXN1840

Phase 2

Wilson Disease

AZD5004

Phase 2

Diabetes Mellitus, Type 2

LAS100977 0.313 μg

Phase 2

Asthma

AZD5069

Phase 2

Asthma

AZD8683, 50 mcg

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

AZD9574

Phase 2

Advanced Solid Malignancies

Formoterol fumarate (6 μg)

Phase 2

Chronic Obstructive Pulmonary Disease - COPD

Osimertinib 80 mg/40 mg

Phase 2

Stage II-IIIB Non-small Cell Lung Carcinoma

ZD1839 (IRESSA™)

Phase 2

Head and Neck Cancer

Market-Implied Move
Regulatory Approvals

Frequently asked questions

What is in AstraZeneca PLC's drug pipeline?

CatalystAlert tracks 416 drug candidates in AstraZeneca PLC's (AZN) pipeline across Phase 3, Phase 2. Its lead program is Baxdrostat and dapagliflozin (Phase 3). Each drug's phase, indication and upcoming catalysts are listed on this page.

When is AstraZeneca PLC's next FDA catalyst?

AstraZeneca PLC's (AZN) next tracked catalyst is a Phase 2 expected August 10, 2026. See the catalyst timeline on this page for the full schedule of PDUFA dates, trial readouts and FDA events.

How do I track AZN biotech catalysts?

Add AZN to your CatalystAlert watchlist for alerts ahead of each catalyst, and follow AstraZeneca PLC's live catalyst calendar, drug pipeline and clinical-trial timeline on this page — sourced from ClinicalTrials.gov, FDA and SEC filings.

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Data is aggregated from public sources (FDA, SEC, ClinicalTrials.gov). While we strive for accuracy, information may be incomplete, delayed, or contain errors. Terms apply