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AstraZeneca PLC

AZN
$273.62B
Mega Cap
NASDAQPharmaceutical PreparationsPharmaceutical🇺🇸EuropeCAMBRIDGE89.9K employees

AstraZeneca plc (/ˌæstrəˈzɛnəkə/) (AZ) is a Swedish–British multinational pharmaceutical and biotechnology company with its headquarters at the Cambridge Biomedical Campus in Cambridge, UK. It has a portfolio of products for major diseases in areas including oncology, cardiovascular, gastrointestinal, infection, neuroscience, respiratory, and inflammation.

Website

Drugs in Pipeline

504

Phase 3 Programs

289

Upcoming Catalysts

35

Next Catalyst

Jul 27, 2026

13d

Market Overview

Stock performance and key metrics

AZN News
Catalyst Timeline

45 upcoming, 10 past

Phase 3Next
Positive

Tezepelumab Phase 3 Results Expected

Jul 14, 2026Tezepelumab368

Primary completion for Tezepelumab trial (NCT05583227) in Eosinophilic Esophagitis

late-stage trial met primary endpoint

Source
Phase 3
Positive

Ravulizumab Phase 3 Est. Readout

July 2026~Ravulizumab12

Primary completion for Ravulizumab trial (NCT05644561) in Generalized Myasthenia Gravis

Camizestrant combination delayed time to first progression by 55% and time to second progression by 37% in patients with advanced HR-positive breast cancer with emergent ESR1 tumor mutation

Source
Phase 3
Negative

Olaparib Phase 3 Est. Readout

July 2026~Olaparib366

Primary completion for Olaparib trial (NCT04884360) in Ovarian Cancer

ATTR-CM trial failure

Source
Earnings

AZN Earnings Report

Jul 27, 2026

EPS Est: $2.52 | FQ end 2026-06

41 more catalysts beyond 14 days

Start a 48-hour free trial to see all upcoming catalysts

Pro

How AZN's past catalysts played out

Drug Pipeline

tralokinumab

Phase 3

Ulcerative Colitis

Symbicort pMDI + budesonide HFA pMDI

Phase 3

Asthma

Aclidinium Bromide / Formoterol Fumarate

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Aclidinium bromide

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

MEDI8897

Phase 3

Respiratory Syncytial Virus Infections

Carboplatin

Phase 3

Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Saxagliptin, 5 mg + insulin

Phase 3

Type 2 Diabetes

Exenatide (AC2993)

Phase 3

Diabetes Mellitus, Type 2

HFO-1234ze(E)

Phase 3

Mucociliary Clearance

Osimertinib

Phase 3

Lung Cancer

Tiotropium

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Terbutaline sulphate

Phase 3

Asthma

Durvalumab

Phase 3

Non-Small Cell Lung Cancer

Budesonide/formoterol (SYMBICORT) pMDI

Phase 3

Chronic Obstructive Pulmonary Disease

ALXN2060

Phase 3

Symptomatic Transthyretin Amyloid Cardiomyopathy

Selumetinib

Phase 3

Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIb - IV

Metformin (blinded)

Phase 3

Type 2 Diabetes

Ciclesonide

Phase 3

Perennial Allergic Rhinitis

Aclidinium bromide 400 μg/Formoterol Fumarate 12 μg (AB/FF 400/12 μg)

Phase 3

Chronic Obstructive Pulmonary Disease

Experimental: Tezepelumab

Phase 3

Chronic Rhinosinusitis With Nasal Polyps

Baxdrostat

Phase 3

Resistant Hypertension

TC-5214

Phase 3

Major Depressive Disorder

Tezepelumab

Phase 3

Moderate to Severe Asthma

AZD9833

Phase 3

ER-Positive HER2-Negative Breast Cancer

Benralizumab Arm A

Phase 3

Moderate to Very Severe Chronic Obstructive Pulmonary Disease

formoterol

Phase 3

Asthma

10mg Rosuvastatin

Phase 3

Renal Failure

Dapagliflozin

Phase 3

Heart Failure With Reduced Ejection Fraction (HFrEF)

Saxagliptin

Phase 3

Type 2 Diabetes

Gefitinib (Iressa)

Phase 3

Cancer

MEDI4736

Phase 3

Squamous Cell Carcinoma of the Head and Neck

Metformin

Phase 3

Type 2 Diabetes Mellitus

Candesartan cilexetil

Phase 3

Hypertension

BCG

Phase 3

Non-Muscle- Invasive Bladder Cancer

Durvalumab (MEDI4736)

Phase 3

Non-muscle-invasive Bladder Cancer

exenatide, long acting release

Phase 3

Type 2 Diabetes Mellitus

Pemetrexed

Phase 3

Non-Small Cell Lung Cancer

Fulvestrant

Phase 3

Breast Cancer

Rosuvastatin (Crestor)

Phase 3

Hypercholesterolemia

Paclitaxel

Phase 3

Metastatic Non-small Cell Lung Cancer

Gemcitabine

Phase 3

Biliary Tract Cancer

Quetiapine Fumarate (Seroquel™) drug, mood stabilizer (mood)

Phase 3

Bipolar Disorder

BGF MDI 320/28.8/9.6 μg

Phase 3

Asthma

Tezepelumab (APFS)

Phase 3

Asthma

Sitagliptin

Phase 3

Type 2 Diabetes

BGF MDI HFO 320/14.4/9.6 μg

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Datopotamab deruxtecan (Dato-DXd)

Phase 3

Non-small Cell Lung Cancer (NSCLC)

Saxagliptin 5mg

Phase 3

Type 2 Diabetes Mellitus

exenatide once weekly

Phase 3

Type 2 Diabetes Mellitus

Gefitinib, raltitrexed

Phase 3

Colorectal Cancer

Salbutamol

Phase 3

Asthma

Zibotentan/Dapagliflozin

Phase 3

Chronic Kidney Disease With High Proteinuria

ABT-335 plus rosuvastatin

Phase 3

Dyslipidemia

Esomeprazole 20 mg

Phase 3

Gastric Ulcer

Acetylsalicylic acid (ASA)

Phase 3

Acute Ischaemic Stroke

ATACAND

Phase 3

Hypertension

AC2993

Phase 3

Diabetes Mellitus, Type 2

Symbicort Turbuhaler

Phase 3

Bronchial Asthma

rosiglitazone

Phase 3

Diabetes Mellitus, Type 2

Durvalumab plus chemotherapy

Phase 3

Small Cell Lung Carcinoma Extensive Disease

Quetiapine Fumarate Extended- Release

Phase 3

Schizophrenia

Insulin glargine

Phase 3

Type 2 Diabetes Mellitus

AZD5156 (Parent study Sentinel Safety Cohort)

Phase 3

COVID-19, SARS-CoV-2

Sodium Zirconium Cyclosilicate (SZC) Reduced Dose Level

Phase 3

Hyperkalaemia

5-fluorouracil

Phase 3

Colorectal Cancer

Saxagliptin 2.5 mg

Phase 3

Type 2 Diabetes Mellitus, CKD and Albuminuria

Oxaliplatin

Phase 3

HER2-positive Gastric Cancer

Saxagliptin + Metformin

Phase 3

Diabetes Mellitus, Type 2

Nirsevimab

Phase 3

Respiratory Syncytial Virus Infections

Quetiapine XR

Phase 3

Major Depressive Disorder

budesonide/formoterol (Symbicort)

Phase 3

Asthma

quetiapine fumarate XR

Phase 3

Anxiety

Pulmicort (budesonide) Respules

Phase 3

Asthma

sunitinib

Phase 3

Papillary Renal Cell Carcinoma

D9421-C capsule 3 mg

Phase 3

Crohn's Disease

Capecitabine

Phase 3

Advanced or Metastatic Breast Cancer

Pulmicort Turbuhaler

Phase 3

Asthma

Camizestrant

Phase 3

Advanced Breast Cancer

Cimetidine

Phase 3

Stress Ulcer Prophylaxis

Ticagrelor 60 mg

Phase 3

Diabetes Mellitus, Type 2

Gemcitabine monotherapy

Phase 3

Biliary Tract Cancer

Cisplatin

Phase 3

Muscle Invasive Bladder Cancer

FLOT chemotherapy

Phase 3

Gastrointestinal Neoplasms

Rilvegostomig

Phase 3

Hepatocellular Carcinoma

Daptomycin

Phase 3

Skin Diseases

5-fluorouracil ( in FOLFOX)

Phase 3

Colorectal Cancer

Quetiapine Fumarate Sustained Release

Phase 3

Major Depressive Disorder

Seroquel (quetiapine)

Phase 3

Schizophrenia

Epanova

Phase 3

Hypertriglyceridemia

MEDI4736 (durvalumab)

Phase 3

Non - Small Cell Lung Cancer NSCLC

Intralipid

Phase 3

Sedation to be Moderate for a Diagnostic Gastrointestinal Endoscopy and Gastrointestinal Endoscopic Polypectomy

exenatide twice daily (BID)

Phase 3

Type 2 Diabetes Mellitus

BGF MDI HFO 320/14.4/9.6μg

Phase 3

COPD (Chronic Obstructive Pulmonary Disease)

Thiazolidinedione (Pioglitazone)

Phase 3

Type 2 Diabetes

Extended release quetiapine (quetiapine XR)

Phase 3

Bipolar Disorder

Palbociclib

Phase 3

Locally Advanced (Inoperable) or Metastatic Breast Cancer

Roxadustat

Phase 3

Anemia

Anastrozole

Phase 3

Breast Cancer

Cisplatin + Gemcitabine

Phase 3

Unresectable Locally Advanced Urothelial Cancer

ABT-143

Phase 3

Dyslipidemia, Hypercholesterolemia, Hypertriglyceridemia

ZD4054

Phase 3

Prostate Cancer

Rosuvastatin

Phase 3

Hypercholesterolemia

Capivasertib

Phase 3

Triple Negative Breast Neoplasms

corn oil control

Phase 3

Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)

Esomeprazole magnesium (Nexium)

Phase 3

Zollinger-Ellison Syndrome

Dapagliflozin 5 mg

Phase 3

Type 1 Diabetes Mellitus

Conventional Asthma Therapy

Phase 3

Asthma

Pemetrexed/Carboplatin

Phase 3

Non-Small Cell Lung Cancer

pravastatin

Phase 3

Hyperlipoproteinemia Type III

candesartan cilexetil (Atacand)

Phase 3

Hypertension

AZD1222

Phase 3

COVID-19

quetiapine fumarate tablets

Phase 3

Schizophrenia

Durvalumab + SoC chemotherapy

Phase 3

Carcinoma, Non-Small-Cell Lung

ZD1839 (Gefitinib)

Phase 3

Carcinoma

fluticasone/salmeterol (Advair)

Phase 3

Asthma

exemestane

Phase 3

Progression-free Survival

Amitriptyline

Phase 3

Major Depressive Disorder

faslodex 500mg

Phase 3

Hormone Receptor Positive Breast Cancer

Single agent chemotherapy

Phase 3

Relapsed Ovarian Cancer, BRCA Mutation, Platinum Sensitivity

Carboplatin+Paclitaxel

Phase 3

Advanced Ovarian Cancer

Olaparib 300mg tablets

Phase 3

Relapsed Ovarian Cancer

Active Comparator: Olaparib tablets

Phase 3

Epithelial Ovarian Cancer

NKTR-118

Phase 3

Opioid-Induced Constipation (OIC)

Osimertinib 80mg/40mg

Phase 3

Non Small Cell Lung Cancer (Stage III)

Zirconium Cyclosilicate

Phase 3

Hyperkalemia

Cediranib

Phase 3

Metastatic Colorectal Cancer

Metformin IR

Phase 3

Type 2 Diabetes

Lomustine Chemotherapy

Phase 3

Recurrent Glioblastoma

Simvastatin

Phase 3

Fredrickson Type IIa & Type IIb Dyslipidaemia

AZD2816

Phase 3

COVID-19

Ezetimibe

Phase 3

Hypercholesterolemia

Rosuvastatin Dose 1

Phase 3

Dyslipidaemia

Roflumilast

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Aclidinium Bromide 200 µg

Phase 3

Chronic Obstructive Pulmonary Disease

Budesonide HFA

Phase 3

Asthma

Symbicort pMDI

Phase 3

Asthma

Acalabrutinib

Phase 3

Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Bicalutamide

Phase 3

Puberty, Precocious

Seroquel SR

Phase 3

Schizophrenia

Esomeprazole

Phase 3

NSAID Associated Gastric Ulcers

Anifrolumab

Phase 3

Lupus Nephritis

Savolitinib

Phase 3

Carcinoma

Budesonide/formoterol Turbuhaler vs Conventional Best Asthma Therapy

Phase 3

Asthma

Tamoxifen

Phase 3

Quality of Life

pioglitazone

Phase 3

Diabetes

Aclidinium bromide 200 μg bid

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Exantide with Dapagliflozin

Phase 3

Diabetes Mellitus

quetiapine fumarate (Seroquel)

Phase 3

Bipolar Disorder

Epoetin alfa

Phase 3

Anemia

Sodium Zirconium Cyclosilicate

Phase 3

Hyperkalemia

AZD5335

Phase 3

Epithelial Ovarian Cancer

divalproex

Phase 3

Bipolar I Disorder

budesonide (Pulmicort)

Phase 3

Asthma

Rosuvastatin calcium

Phase 3

Hypercholesteremia

AZD1152

Phase 3

Acute Myeloid Leukemia

Zolmitriptan

Phase 3

Migraine

Salmeterol/fluticasone Diskus

Phase 3

Asthma

Quetiapine Fumarate (SEROQUEL) Extended-Release (XR)

Phase 3

Schizophrenia

MEDI3250

Phase 3

Healthy Japanese Children Age 7 Years Through 18 Years

AZD0780

Phase 3

Heterozygous Familial Hypercholesterolaemia

exenatide/insulin glargine

Phase 3

Type 2 Diabetes Mellitus

Candesartan

Phase 3

Congestive Heart Failure

Ranitidine

Phase 3

Gastric Ulcer

Atorvastatin

Phase 3

Coronary Atherosclerosis

lithium

Phase 3

Bipolar I Disorder

metoprolol succinate

Phase 3

Hypertension

Hydrochlorothiazide

Phase 3

Hypertension

Exenatide once weekly suspension

Phase 3

Diabetes Mellitus, Type 2

budesonode bid + terbutaline 'as needed'

Phase 3

Asthma

Olanzapine, risperidone

Phase 3

Schizophrenia

insulin lispro

Phase 3

Type 2 Diabetes Mellitus

Metformin immediate release (IR)

Phase 3

Type 2 Diabetes

Saxagliptin plus metformin IR

Phase 3

Type 2 Diabetes Mellitus

Symbicort TBH - Turbuhaler

Phase 3

Asthma

Olive oil, 4g

Phase 3

Hypertriglyceridemia

Budesonide HFA pMDI

Phase 3

Asthma

Fluticasone

Phase 3

Asthma

Etoposide

Phase 3

Extensive-stage Small Cell Lung Cancer

glipizide

Phase 3

Type 2 Diabetes

Terbutaline Turbuhaler®

Phase 3

Asthma

Esomeprazole Na

Phase 3

Bleeding Peptic Ulcer

Linaclotide

Phase 3

Irritable Bowel Syndrome With Constipation (IBS-C)

Enfortumab Vedotin

Phase 3

Muscle Invasive Bladder Cancer

Budesonide/albuterol metered-dose inhaler 160/180 μg

Phase 3

Asthma, Exercise-Induced

Quetiapine fumarate (Seroquel) SR

Phase 3

Affective Psychosis, Bipolar

(Osimertinib cohort, single-arm, open-label separate cohort)

Phase 3

Carcinoma, Non-Small-Cell Lung

BFF MDI 320/9.6 μg

Phase 3

Asthma

Budesonide/formoterol pMDI

Phase 3

Asthma

NXY-059

Phase 3

Intracerebral Hemorrhage

CRESTOR

Phase 3

Heart Failure

Pertuzumab

Phase 3

Breast Neoplasms

Seroquel Sustained Release (SR)

Phase 3

Schizophrenic Disorder

cisplatin + fluorouracil

Phase 3

Esophageal Squamous Cell Carcinoma

Ravulizumab

Phase 3

Thrombotic Microangiopathy

Letrozole

Phase 3

Breast Cancer, Early Breast Cancer

CAEL-101

Phase 3

AL Amyloidosis

AZD7442

Phase 3

COVID-19

Sebelipase alfa (SBC-102)

Phase 3

Lysosomal Acid Lipase Deficiency

Eculizumab

Phase 3

Atypical Hemolytic Uremic Syndrome

Surovatamig

Phase 3

B-cell Non-Hodgkin Lymphoma

Ticagrelor

Phase 3

Acute Coronary Syndrome

Volrustomig

Phase 3

Non-small Cell Lung Cancer

Eculizumab (Soliris®)

Phase 3

Shiga-like Toxin-producing Escherichia Coli

Andexanet

Phase 3

Bleeding

Epanova® (omega-3 carboxylic acids)

Phase 3

Diabetes Mellitus, Type 2

Casdatifan

Phase 3

Advanced Clear Cell Renal Cell Carcinoma

ALXN1850

Phase 3

Hypophosphatasia

ALXN2220

Phase 3

Transthyretin Amyloid Cardiomyopathy

sebelipase alfa

Phase 3

Cholesterol Ester Storage Disease (CESD)

C5 Inhibitor

Phase 3

Paroxysmal Nocturnal Hemoglobinuria

Danicopan

Phase 3

C3 Glomerulonephritis

asfotase alfa

Phase 3

Hypophosphatasia

pexelizumab in conjunction with CABG

Phase 3

Coronary Artery Disease

Tozorakimab Dose Regimen 1

Phase 3

Chronic Obstructive Pulmonary Disease

Sonesitatug vedotin

Phase 3

Gastric Cancer

Baxdrostat and dapagliflozin

Phase 3

Heart Failure

Nab-paclitaxel

Phase 3

Breast Cancer

Treatment A : Budesonide, Glycopyrronium, and Formoterol Fumarate

Phase 3

Chronic Obstructive Pulmonary Disease

Chemotherapy

Phase 3

Anticancer Treatment

Saruparib (AZD5305)

Phase 3

Ovarian Cancer

Esomeprazole IV

Phase 3

Gastrointestinal Hemorrhage

exenatide twice daily

Phase 3

Type 2 Diabetes Mellitus

Ciclesonide nasal

Phase 3

Rhinitis, Allergic, Perennial

fostamatinib

Phase 3

Rheumatoid Arthritis

Benralizumab Arm B

Phase 3

Moderate to Very Severe Chronic Obstructive Pulmonary Disease

D961H capsule 10mg

Phase 3

Reflux Esophagitis

ZD9393 (Zoladex) 10.8 mg

Phase 3

Breast Cancer

Olaparib

Phase 3

Breast Cancer Metastatic

Budesonide/formoterol Turbuhaler

Phase 3

Asthma

ABT-335 and rosuvastatin calcium

Phase 3

Hypercholesterolemia

Omeprazole

Phase 3

Reflux Esophagitis

Formoterol Turbuhaler® 4.5mg

Phase 3

Chronic Obstructive Pulmonary Disease

Quetiapine Fumarate

Phase 3

Bipolar Disorder

Osimertinib (AZD9291) pemetrexed cisplatin or carboplatin

Phase 3

Non-small Cell Lung Cancer

Seroquel®, quetiapine fumarate (atypical antipsychotic)

Phase 3

Bipolar Disorder

cyclophosphamide, bortezomib, and dexamethasone (CyBorD) regimen

Phase 3

AL Amyloidosis

AZD9291

Phase 3

Advanced Non Small Cell Lung Cancer

Baxdrostat/dapagliflozin

Phase 3

Chronic Kidney Disease and Hypertension

Saruparib

Phase 3

Prostate Cancer

Sulphonylurea

Phase 3

Type 2 Diabetes

Datopotamab Deruxtecan

Phase 3

Non-small Cell Lung Cancer

Saxagliptin, Onglyza

Phase 3

Type 2 Diabetes Mellitus

Abiraterone Acetate

Phase 3

Hormone-Sensitive Prostate Cancer

Theophylline

Phase 3

Asthma

Anastrazole (Arimidex)

Phase 3

Breast Cancer

Clopidogrel

Phase 3

Stable Coronary Artery Disease

Acetylsalicylic acid ASA

Phase 3

Acute Coronary Syndrome

Sodium Zirconium Cyclosilicate (ZS) 10g

Phase 3

Hyperkalemia

Oleclumab

Phase 3

Non-Small Cell Lung Cancer

Sodium Zirconium Cyclosilicate (ZS)

Phase 3

Hyperkalemia

Gefitinib

Phase 3

Non-Small Cell Lung Cancer

Tremelimumab

Phase 3

Advanced Hepatocellular Carcinoma

Aclidinium Bromide/Formoterol Fumarate

Phase 3

Chronic Obstructive Pulmonary Disease

Pramlintide acetate

Phase 3

Diabetes Mellitus, Type 1

Tozorakimab

Phase 3

Chronic Obstructive Pulmonary Disease (COPD)

Quetiapine

Phase 3

Major Depressive Disorder

Glimepiride

Phase 3

Type 2 Diabetes

Medi-546

Phase 3

Systemic Lupus Erythematosus

AZD9291 Dosing

Phase 3

Lung Cancer

budesonide

Phase 3

Asthma

budesonide bid + terbutaline 'as needed'

Phase 3

Asthma

Ciclesonide nasal spray

Phase 3

Hay Fever

AZD4831

Phase 3

Heart Failure With Preserved Ejection Fraction

Seasonal influenza virus vaccine

Phase 3

Asthma

Rosuvastatin 20mg

Phase 3

Homozygous Familial Hypercholesterolemia (HoFH)

Budesonide/Formoterol

Phase 3

Asthma

candsartan cilexetil

Phase 3

Hypertension

Gemcitabine/Cisplatin

Phase 3

Biliary Tract Cancer

Saxagliptin 5 mg

Phase 3

Type 2 Diabetes Mellitus

Nexium 20mg

Phase 3

Erosive Esophagitis

Quetiapine SR

Phase 3

Major Depressive Disorder

Eplontersen

Phase 3

Transthyretin Amyloid Cardiomyopathy

omefas

Phase 3

Severe Hypertriglyceridemia

pexelizumab

Phase 3

Cardio-pulmonary Bypass

Benralizumab (Medi-563)

Phase 3

Asthma

Lithium carbonate

Phase 3

Acute Bipolar Depression

Metformin XR

Phase 3

Type 2 Diabetes

Esomeprazole (D961H) twice daily

Phase 3

Refractory Reflux Esophagitis

Dato-DXd

Phase 3

Breast Cancer

SSRI/Clomipramine

Phase 3

Obsessive Compulsive Disorder

MEDI4736 + Tremelimumab

Phase 3

Recurrent or Metastatic PD-L1-positive or -Negative Squamous Cell Carcinoma of the Head and Neck SCCHN

Escitalopram oxylate

Phase 3

Generalized Anxiety Disorder

quetiapine fumarate or valproate

Phase 3

Bipolar Disorder

Docetaxel

Phase 3

Prostate Cancer

Mepolizumab

Phase 3

Eosinophilic Granulomatous Vasculitis

Dapagliflozin 10 mg

Phase 3

Diabetes Mellitus, Non-Insulin-Dependent

Symbicort

Phase 3

COPD Patients

Benralizumab

Phase 3

Asthma

exenatide

Phase 3

Type 2 Diabetes Mellitus

AC2993 (exenatide)

Phase 2

Diabetes Mellitus

AZD6234

Phase 2

Obesity/Overweight

MEDI6570

Phase 2

Coronary Heart Disease (CHD)

Tremelimumab monotherapy

Phase 2

Urothelial Bladder Cancer

B - Exenatide 10 mcg twice daily

Phase 2

Diabetes Mellitus, Type 2

metreleptin

Phase 2

Overweight

ZD1839

Phase 2

Mesothelioma

Sovaprevir

Phase 2

Hepatitis C, Chronic

Bis-Choline Tetrathiomolybdate

Phase 2

Wilson Disease

AZD7009, no generic name available

Phase 2

Atrial Fibrillation

Ticagrelor Dose 1a + Dose 2a

Phase 2

Investigation of Platelet Aggregation in Paediatric Patients With Sickle Cell Disease

AZD7760

Phase 2

Staphylococcus Aureus

Ramucirumab

Phase 2

Non-Small Cell Lung Cancer

SBC-103

Phase 2

Mucopolysaccharidosis IIIB

AZD4573

Phase 2

Advanced Haematological Malignancies

AZD3470

Phase 2

Lymphoma

AZD5069 50mg

Phase 2

Scientific Terminology Chronic Obstructive Pulmonary Disease (COPD)

AZD3241

Phase 2

Multiple System Atrophy, MSA

AZD1940

Phase 2

Pain

AZD2693

Phase 2

Nonalcoholic Steatohepatitis

AZD9793 Intravenous (IV) monotherapy

Phase 2

Hepatocellular Carcinoma

Anastrazole

Phase 2

Breast Cancer

Gefitinib, Cisplatin and Radiotherapy

Phase 2

Cancer of Head and Neck

AZD4901 (oral)

Phase 2

Polycystic Ovary Syndrome (PCOS), Female Endocrine Disorder

MEDI7352

Phase 2

Painful Osteoarthritis of the Knee

MEDI0382 low dose

Phase 2

Diabetes Mellitus, Type 2

AZD2927

Phase 2

Arrhythmia

cediranib and olaparib

Phase 2

Recurrent Platinum Resistant Ovarian Cancer

AZD0901

Phase 2

Gastric Cancer

AZD0022

Phase 2

Advanced Solid Tumours

AZD0754

Phase 2

Metastatic Prostate Cancer

lesogaberan (AZD3355)

Phase 2

Gastroesophageal Reflux Disease

pramlintide acetate 360 mcg

Phase 2

Overweight

Tiotropium 18 μg once-daily

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

AZD1446

Phase 2

Adult ADHD

AZD5363 when combined with weekly paclitaxel.

Phase 2

Advanced or Metastatic Breast Cancer

ACH-0144471

Phase 2

Paroxysmal Nocturnal Hemoglobinuria

AZD4818

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

ACH-0141625 (Sovaprevir)

Phase 2

Hepatitis C

Tarperprumig

Phase 2

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

800 μg AZD7594 once daily

Phase 2

Asthma

AZD1305

Phase 2

Atrial Fibrillation

MEDI-545

Phase 2

Systemic Lupus Erythematosus

AZD0120

Phase 2

Lupus Erythematosus, Systemic

AZD5718

Phase 2

Coronary Artery Disease

AZD9056

Phase 2

Rheumatoid Arthritis

Casodex

Phase 2

Gynaecomastia

Lenvatinib

Phase 2

Hepatocellular Carcinoma

AZD5069

Phase 2

Asthma

AZD5423

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

AZD8683, 50 mcg

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

AZD9574

Phase 2

Advanced Solid Malignancies

Formoterol fumarate (6 μg)

Phase 2

Chronic Obstructive Pulmonary Disease - COPD

Osimertinib 80 mg/40 mg

Phase 2

Stage II-IIIB Non-small Cell Lung Carcinoma

Ticagrelor Tablets

Phase 2

Coronary Artery Disease

Formoterol Fumarate in the Pressair DPI, Low Dose

Phase 2

Asthma

Bertilimumab

Phase 2

Pemphigoid, Bullous

Sebelipase alfa 0.35 mg/kg

Phase 2

Cholesterol Ester Storage Disease(CESD)

ZD1839 (IRESSA™)

Phase 2

Head and Neck Cancer

KU-0059436 (AZD2281)(PARP inhibitor)

Phase 2

Ovarian Neoplasm

Exenatide LAR

Phase 2

Type 2 Diabetes Mellitus

AZD5492

Phase 2

B-cell Malignancies

Part A:AZD8233

Phase 2

Dyslipidemia

plevitrexed

Phase 2

Fallopian Tube Cancer

Montelukast

Phase 2

Asthma

AZD1981

Phase 2

Asthma

AZD5851

Phase 2

Hepatocellular Carcinoma

Verinurad 9 mg+Febuxostat 80 mg

Phase 2

Hyperuricemia

AZD0865

Phase 2

GERD Without Erosive Esophagitis

Salmeterol

Phase 2

Chronic Obstructive Pulmonary Disease

Atuliflapon

Phase 2

Asthma

exenatide (LY2148568)

Phase 2

Type 2 Diabetes Mellitus

0.5% Roflumilast Cream

Phase 2

Atopic Dermatitis

AZD2423

Phase 2

Chronic Obstructive Pulmonary Disease

AZD7789

Phase 2

Carcinoma, Non-Small-Cell Lung

Aclidinium 400 μg / Formoterol 12 μg

Phase 2

Chronic Obstructive Pulmonary Disease

Ceralasertib

Phase 2

Advanced Solid Tumours

Verinurad

Phase 2

Chronic Kidney Disease

AZD8871

Phase 2

Chronic Obstructive Pulmonary Disease

MEDI3506

Phase 2

Atopic Dermatitis

AC2993 2.5 mcg

Phase 2

Diabetes Mellitus, Non-Insulin-Dependent

Epanova (4 g) and Lovaza (4 g)

Phase 2

Severe Hypertriglyceridemia

AZD3480

Phase 2

ADHD

Biological: AZD3152

Phase 2

COVID-19, SARS-CoV-2

VKA INR 2-3

Phase 2

Persistent or Permanent Nonvalvular Atrial Fibrillation

CP-675,206

Phase 2

Malignant Melanoma

GC012F (AZD0120)

Phase 2

Relapsed/ Refractory Multiple Myeloma

AZD8848

Phase 2

Allergic Asthma

AZD4117

Phase 2

Influenza A

Neoadjuvant Olaparib monotherapy group

Phase 2

Breast Cancer

Aclidinium bromide 100 μg bid

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

AC2592

Phase 2

Congestive Heart Failure

AZD7325

Phase 2

Anxiety Disorders

AZD5462

Phase 2

Chronic Heart Failure

AZD7594 DPI 55μg/50μg.

Phase 2

Asthma

AZD8630

Phase 2

Asthma

AZD2389

Phase 2

Liver Fibrosis

ER tablet 25 mg AZD3241

Phase 2

Parkinson's Disease

Iressa

Phase 2

Locally Advanced Prostate Cancer

Gefitinib, radiotherapy

Phase 2

Non-Metastatic Prostate Cancer

AZD9164

Phase 2

Chronic Obstructive Pulmonary Disease

AZD2327

Phase 2

Anxious Major Depressive Disorder

AZD8421

Phase 2

ER+ HER2- Advanced Breast Cancer

AZD9773 (CytoFab)

Phase 2

Severe Sepsis

AZD2936

Phase 2

Non-Small-Cell Lung Carcinoma

AZD2281

Phase 2

Ovarian Neoplasms

Cediranib 30 - 90 mg

Phase 2

Cancer

ACH-126,443

Phase 2

Hepatitis B, Chronic

80/2.25 μg Symbicort pMDI

Phase 2

Asthma

AZD9977

Phase 2

Heart Failure

ALXN2420

Phase 2

Acromegaly

ALXN1210

Phase 2

PNH

AZD3427

Phase 2

Pulmonary Hypertension (World Health Organization Group 2)

CP-675,206 and leuprolide acetate and bicalutamide

Phase 2

Prostatic Neoplasms

Anastrozole and goserelin

Phase 2

Breast Cancer

ALXN2350

Phase 2

BAG3 Mutation Associated Dilated Cardiomyopathy

AZD6765

Phase 2

Treatment Resistant Major Depressive Disorder

AZD9829

Phase 2

Hematological Malignancies

Omega-3 carboxylic acid

Phase 2

Non-alcoholic Fatty Liver Disease (NAFLD

terbutaline

Phase 2

Exercise Induced Asthma

Gefitinib and capecitabine

Phase 2

Colorectal Cancer

Dacarbazine

Phase 2

Melanoma

Monalizumab

Phase 2

Non-small Cell Lung Cancer

AZD0171

Phase 2

Locally Advanced or Metastatic Solid Tumours

Osimertinib + Savolitinib

Phase 2

Non-Small Cell Lung Cancer

Anastrozole (ARIMIDEX™)

Phase 2

Gynecomastia

AB248

Phase 2

Advanced or Metastatic Non-small Cell Lung Cancer

AZD2066

Phase 2

Reflux Episodes

AZD5004

Phase 2

Diabetes Mellitus, Type 2

LAS100977 0.313 μg

Phase 2

Asthma

Goserelin acetate

Phase 2

Advanced Breast Cancer

AZD4360

Phase 2

Gastric Cancer

AZD9773

Phase 2

Severe Sepsis

Cotadutide

Phase 2

Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis

Selumetinib 75 mg

Phase 2

Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIb - IV

AZD8233

Phase 2

Hyperlipidaemia

AZD3241 300 mg BID

Phase 2

Parkinson's Disease

AZD6750

Phase 2

Melanoma

AZD1656

Phase 2

Type 2 Diabetes Mellitus

AS MDI

Phase 2

Asthma

Adavosertib

Phase 2

Ovarian, Fallopian Tube, Peritoneal Cancer, P53 Mutation

SoC: cyclophosphamide, bortezomib, and Dexamethasone (CyBorD)

Phase 2

AL Amyloidosis

AZP-3601

Phase 2

Chronic Hypoparathyroidism

Aclidinium/formoterol 400/12μg

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

AZD2171

Phase 2

Metastatic Colorectal Cancer

MEDI4736 monotherapy

Phase 2

Metastatic Pancreatic Ductal Adenocarcinoma

AZD9567

Phase 2

Diabetes Mellitus, Type 2

AZD9668

Phase 2

Chronic Obstructive Pulmonary Disease

AZD6621

Phase 2

Prostate Cancer

Cerdulatinib

Phase 2

Follicular Lymphoma (FL/Indolent NHL)

AZD8601

Phase 2

Heart Failure

Abiraterone

Phase 2

Metastatic Castration-resistant Prostate Cancer

AZD0486

Phase 2

Chronic Lymphocytic Leukaemia

Lamivudine

Phase 2

HIV Infections

AZD6094

Phase 2

Papillary Renal Cell Cancer

sibutramine

Phase 2

Overweight

Sodium Zirconium Cyclosilicate(ZS)

Phase 2

Hyperkalemia

IR (Immediate-Release) quetiapine fumarate (drug)

Phase 2

Schizophrenia

AZD3199

Phase 2

COPD

AC2307

Phase 2

Obesity

AZD5213

Phase 2

Mild Cognitive Impairment

AZD8931

Phase 2

Neoplasms

Administration of ceralasertib

Phase 2

Adv Solid Malig - H&N SCC, ATM Pro / Def NSCLC, Gastric, Breast and Ovarian Cancer

Mitiperstat (AZD4831)

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

AZD7798

Phase 2

Crohn's Disease

Insulin

Phase 2

Type 2 Diabetes Mellitus

AZD0530

Phase 2

Breast Cancer

AZD5305

Phase 2

Ovarian Cancer

AZD4512

Phase 2

B-cell Non-Hodgkin Lymphoma

AZD4017

Phase 2

Raised Intraocular Pressure

AZD4604

Phase 2

Asthma

Fluorouracil (5-FU)

Phase 2

Gastric Cancer

AZD6244

Phase 2

Non Small Cell Lung Cancer

AZD1163

Phase 2

Rheumatoid Arthritis

AZD2624

Phase 2

Schizophrenia

Interferon beta-1a Nebuliser solution 48 μg/mL

Phase 2

Asthma

AS MDI 90 μg

Phase 2

Asthma

AZD8871 100 µg

Phase 2

Chronic Obstructive Pulmonary Disease COPD

RDEA3170

Phase 2

Gout and Hyperuricemia

AZD9550

Phase 2

Overweight and Obesity

D9421-C, 9mg

Phase 2

Crohn's Disease

AZD2115

Phase 2

COPD

Vinorelbine

Phase 2

Non-Small Cell Lung Cancer

FOLFIRI (Fluorouracil (5-FU), leucovorin, irinotecan)

Phase 2

Metastatic Colorectal Cancer

CIN-107

Phase 2

Uncontrolled Hypertension

600 mg AZD7442 IV

Phase 2

Coronavirus Disease 2019 (COVID-19)

budesonide/formoterol, 2x 200/6 microgram. 4 times daily

Phase 2

Chronic Obstructive Pulmonary Disease

AZD 8529

Phase 2

Schizophrenia

Cotadutide 100 micrograms

Phase 2

Type 2 Diabetes Mellitus

Elvucitabine

Phase 2

Human Immunodeficiency Virus (HIV)-1 Infection

5-flourouracil

Phase 2

Squamous Cell Cancer

Durvalumab and Tremelimumab

Phase 2

Platinum Refractory Extensive-Stage Small Cell Lung Carcinoma

ZD4054 10 mg

Phase 2

Prostatic Neoplasms

AZD4635

Phase 2

Prostate Cancer

AZD0837

Phase 2

Nonvalvular Atrial Fibrillation

ALXN2030

Phase 2

Antibody-Mediated Rejection

5-Fluorouracil (5-FU)

Phase 2

Gastroesophageal Adenocarcinoma

Irinotecan

Phase 2

Colorectal Cancer

ALXN1920

Phase 2

Primary Membranous Nephropathy

Danvatirsen

Phase 2

Non-Small Cell Lung Cancer

ALXN1840

Phase 2

Wilson Disease

MEDI2070

Phase 2

Crohn's Disease

Aclidinium 200 μg / formoterol 12 μg

Phase 2

Chronic Obstructive Pulmonary Disease

Temozolomide

Phase 2

Melanoma

AZD9150

Phase 2

Advanced Solid Tumors & Metastatic Squamous Cell Carcinoma of the Head and Neck

AZD3355

Phase 2

GERD

AZD8205

Phase 2

Breast Cancer

Leucovorin LV

Phase 2

Endometrial Cancer

gefitinib and fulvestrant

Phase 2

Breast Cancer

ICI35,868 (propofol)

Phase 2

Gastrointestinal Endoscopy

Pramlintide and Metreleptin

Phase 2

Obesity

BMS-512148

Phase 2

Diabetes Mellitus, Type 2

AZD7648

Phase 2

Advanced Malignancies

Ciclesonide/Formoterol Combination

Phase 2

Asthma

Olaparib Continuous (28-Day cycle) 300 mg BD.

Phase 2

Metastatic Triple Negative Breast Cancer

Market-Implied Move
Regulatory Approvals

Frequently asked questions

What is in AstraZeneca PLC's drug pipeline?

CatalystAlert tracks 504 drug candidates in AstraZeneca PLC's (AZN) pipeline across Phase 3, Phase 2. Its lead program is tralokinumab (Phase 3). Each drug's phase, indication and upcoming catalysts are listed on this page.

When is AstraZeneca PLC's next FDA catalyst?

AstraZeneca PLC's (AZN) next tracked catalyst is a Acquisition expected July 8, 2026. See the catalyst timeline on this page for the full schedule of PDUFA dates, trial readouts and FDA events.

How do I track AZN biotech catalysts?

Add AZN to your CatalystAlert watchlist for alerts ahead of each catalyst, and follow AstraZeneca PLC's live catalyst calendar, drug pipeline and clinical-trial timeline on this page — sourced from ClinicalTrials.gov, FDA and SEC filings.

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Data is aggregated from public sources (FDA, SEC, ClinicalTrials.gov). While we strive for accuracy, information may be incomplete, delayed, or contain errors. Terms apply