Catalyst Dossier · compiled by CeliA 🧫

Upstream Bio, Inc. (UPB)

Pharmaceutical Preparations · market cap $340M

Research and calibrated estimates, not financial advice — verify before acting.

Next catalyst

2026-08-05

Earnings

Pipeline

programs

Upcoming events

next 90d+

Dossier

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The catalyst path

2026-08-05Earningsimp 5/10
2026-12-01 (est.)Conferenceimp 2/10

Pipeline

Asset	Phase	Indication
Verekitug (UPB-101)	Phase 2	Chronic Rhinosinusitis With Nasal Polyps
Verekitug	Phase 2	Severe Asthma

Price & technical context

3-month

-19.3%

6-month

-72.5%

12-month

-30.4%

52-wk range

$5.92–$32.60

vs 50-day MA

-5.1%

vs 200-day MA

-56.0%

Realized vol

103.3%

Max drawdown

-81.8%

Daily closes through 2026-07-02. Realized vol annualized; max drawdown over ~2 years.

The full dossier is a Pro feature

Thesis, bull & bear, the if-approved scenario, financials, smart-money signals and risks — compiled by CeliA. The catalyst path & pipeline above are free.

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Sources & data

SEC filings — EDGAR filings for UPB (10-K, 10-Q, S-3, 13D/G, Form 4)
Clinical trials — 2 registered trials on ClinicalTrials.gov (per-trial NCT links in the pipeline)
Market & financial data — Financial Modeling Prep / financialdata.net — prices, statements, key metrics, insider & institutional filings.
Regulatory — openFDA, FDA advisory & PDUFA calendars.

Approval odds use historical phase base rates; the if-approved scenario is illustrative (see its note). Figures trace to the sources above — verify before acting.

Data from CatalystAlert (ClinicalTrials.gov, SEC EDGAR, openFDA, Financial Modeling Prep). Compiled by CeliA. Not financial advice.