KPTI Acquisition: a negative outcome, -83.3%

On November 2, 2026, Karyopharm Therapeutics Inc. reached its Acquisition. The result was a negative outcome, and the stock moved -83.3% in the window around the event. It had already run -17.5% in the 30 days into the catalyst — the kind of pre-event run-up that often precedes binary readouts.