June 1, 2025 · Phase 1 readout
ALNY Phase 1 readout: a positive outcome, +7.1%
On June 1, 2025, ALN-APP — Alnylam Pharmaceuticals, Inc. (Alzheimer Disease) reached its Phase 1 readout. The result was a positive outcome, and the stock moved +7.1% in the window around the event. It had already run +12.9% in the 30 days into the catalyst — the kind of pre-event run-up that often precedes binary readouts.
The move
$304.56
1d before
$326.09
Event day
$306.09
1d after
$300.83
5d after
Pre-catalyst setup
+12.9%
30-day run-up
5151%
30-day volatility
3.0×
volume spike
