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Cell (In Press)
Original article

Dynamic dimer-of-dimers architecture defines Mg2+ transport in human CNNM4

CNNM4Positive
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Summary

Research article describing cryo-electron microscopy structures of human CNNM4 protein revealing its dimer-of-dimers architecture and mechanism for Mg2+/Na+ exchange. The study identifies an intracellular acidic patch potentially involved in cellular magnesium sensing.

Importance:3/10
Sentiment:
0.30
researchstructural_biologycryo-EMmagnesiumion_transport
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Published by Cell (In Press) on July 24, 2026 12:00 AM

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