Astellas Doses First Patient in Phase 3 Study of setidegrasib in Previously Treated KRAS G12D-Mutated Advanced Non-Small Cell Lung Cancer

Phase 3setidegrasibdocetaxelPositive

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Summary

Astellas has dosed the first patient in a Phase 3 study evaluating setidegrasib, a KRAS G12D-targeted protein degrader, versus docetaxel in previously treated patients with advanced non-small cell lung cancer. This marks the second Phase 3 study of setidegrasib initiated within six months.

Clinical Trial Data

Phase

Phase 3

Outcome Details

First patient dosed in Phase 3 study

Importance:6/10

Sentiment:

0.60

Phase 3KRAS G12Dprotein degraderNSCLConcologytrial initiation

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Published by PR Newswire Pharma on September 23, 2026 11:30 PM

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