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Cancer Network
Original article

<![CDATA[Stratifying By Baseline Tumor Cell Density Indicates Treatment Effect Heterogeneity in Rectal Cancer]]>

Data ReadoutpositivePositive
AI Analysis

Summary

A post-hoc analysis of the ARISTOTLE trial demonstrated that rectal cancer patients with high baseline tumor cell density experienced improved disease-free and overall survival, suggesting treatment effect heterogeneity based on tumor cell density stratification.

Clinical Trial Data

Primary Endpoint

Met

Outcome Details

Post-hoc analysis of ARISTOTLE trial showed patients with high tumor cell density had improved disease-free survival (DFS) and overall survival (OS)

Importance:5/10
Sentiment:
0.60
rectal cancerpost-hoc analysisARISTOTLE trialtumor cell densityDFSOStreatment stratification

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Published by Cancer Network on August 13, 2026 7:00 PM

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