Cell (In Press)Original article
LEF1 and niche factors determine T cell stemness across chronic diseases
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Summary
Research identifies LEF1 and niche-derived factors as essential regulators of stem-like CD8 T cell function in chronic disease settings. The study explores mechanisms of T cell stemness in persistent antigen environments including autoimmunity and chronic infection.
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basic_researchimmunologyT_cellchronic_diseaseautoimmunitychronic_infection
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Published by Cell (In Press) on July 1, 2026 12:00 AM