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Cancer Network
High ImpactOriginal article

<![CDATA[Trastuzumab Botidotin Prolongs PFS vs T-DM1 in HER2+ Advanced Breast Cancer]]>

Phase 3positiveTrastuzumab botidotinTrastuzumab emtansinePositive
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Summary

Trastuzumab botidotin demonstrated superior efficacy to T-DM1 in the Phase 3 KL166-III-06 trial for HER2-positive advanced breast cancer, more than doubling median progression-free survival.

Clinical Trial Data

Phase

Phase 3

Primary Endpoint

Met

Outcome Details

Trastuzumab botidotin more than doubled median PFS vs trastuzumab emtansine

Importance:8/10
Sentiment:
0.80
oncologybreast cancerHER2-positivePhase 3PFS
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Published by Cancer Network on September 15, 2026 8:00 PM

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