Cell (In Press)Original article
A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions
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Summary
Researchers developed a scalable viral ORFeome library containing ~13,000 barcoded viral open reading frames from >500 viral species to enable functional genomic screens. The platform identified viral regulators of cellular proliferation, antigen presentation, and interferon signaling.
Importance:3/10
Sentiment:
0.60
viral ORFeome libraryfunctional genomicshost-pathogen interactionsscreening platformresearch tool
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Published by Cell (In Press) on July 2, 2026 12:00 AM