CatalystAlert

Search CatalystAlert

Search for companies, drugs, and catalysts

Search CatalystAlert

Search for companies, drugs, and catalysts

MERCK

MRK
$364.35B
Mega Cap
NASDAQPharmaceutical PreparationsPharmaceuticals🇺🇸North AmericaRAHWAY75.0K employees

Merck & Co., Inc. is an American multinational pharmaceutical company headquartered in Rahway, New Jersey. The company does business as Merck Sharp & Dohme or MSD outside the United States and Canada. The company is ranked fifth on the list of largest biomedical companies by revenue.

Website

Drugs in Pipeline

837

Phase 3 Programs

448

Upcoming Catalysts

50

Next Catalyst

Oct 23, 2026

20d

Market Overview

Stock performance and key metrics

MRK News
Catalyst Timeline

50 upcoming, 5 past

No catalysts found.

50 more catalysts beyond 14 days

Start a 48-hour free trial to see all upcoming catalysts

Pro

Upcoming FDA decisions

How MRK's past catalysts played out

Phase 3 readoutAug 2026+13%Phase 3 readoutAug 2026+13%PDUFA decisionJan 2023-3%PDUFA decisionAug 2021+1%
Drug Pipeline

ULO

Phase 3

Human Immunodeficiency Virus Type 1 (HIV-1) Infection

M-M-R™II manufactured with recombinant Human Albumin (rHA) and VARIVAX®

Phase 3

Measles

100 mg clindamycin /800 mg ketoconazole vaginal ovule

Phase 3

Vaginosis, Bacterial

Telcagepant 140 mg

Phase 3

Migraines

Telcagepant 300 mg soft gel capsules

Phase 3

Migraine

CXA-201

Phase 3

Complicated Urinary Tract Infection

Rotarix™

Phase 3

Pneumococcal Infections

QIV

Phase 3

Pneumonia, Pneumococcal

Acetaminophen/Paracetamol

Phase 3

Migraine Disorders

MK-3415

Phase 3

Clostridium Difficile Infection

Leucovorin/ levoleucovorin

Phase 3

Metastatic Colorectal Cancer

epinastine nasal spray, low concentration, low dose volume

Phase 3

Seasonal Allergic Rhinitis

Letermovir tablet

Phase 3

Cytomegalovirus Infection

peginterferon alfa-2b (PEG2b) (SCH 54031)

Phase 3

Hepatitis C, Chronic

Prulifloxacin

Phase 3

Acute Gastroenteritis in Adult Travelers

Efalizumab

Phase 3

Moderate to Severe Psoriasis

Suvorexant High Dose (HD)

Phase 3

Primary Insomnia

FOLFIRI (5-Fluorouracil, Folinic acid, Irinotecan)

Phase 3

Epidermal Growth Factor Receptor (EGFR) Expressing Metastatic Colorectal Cancer

Valganciclovir

Phase 3

CMV Disease

MK-7625A 1.5 g (ceftolozane 1 g/tazobactam 0.5 g)

Phase 3

Intra-abdominal Infection

Uridine 5'-Triphosphate (UTP) Solution for Inhalation

Phase 3

Lung Cancer

S-1

Phase 3

Gastric Cancer

Glycopyrrolate

Phase 3

Surgical Procedures, Elective

Rotavirus Vaccine, Live, Oral, Pentavalent (V260, RotaTeq™)

Phase 3

Rotavirus

MK0966 / Duration of Treatment: 1 Days

Phase 3

Pain, Postoperative Arthroscopy

MK0524A, /Duration of Treatment : 4 Weeks

Phase 3

Flushing

Alviompan

Phase 3

Bowel Dysfunction

taranabant

Phase 3

Smoking

regorafenib

Phase 3

Colorectal Cancer

V221, measles, mumps, rubella and varicella (Oka/Merck) virus vaccine live / Duration of Treatment: 12 weeks

Phase 3

Measles

Rebif® New Formulation (IFN-beta-1a, RNF)

Phase 3

Multiple Sclerosis, Relapsing-Remitting

V501, Gardasil, Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine / Duration of Treatment : 4 Years

Phase 3

Cervical Cancer

sitagliptin phosphate (+) metformin hydrochloride

Phase 3

Type 2 Diabetes Mellitus

Peginterferon alfa-2b (PEG)

Phase 3

Hepatitis C, Chronic

Cladribine Low Dose

Phase 3

Generalized Myasthenia Gravis

Rocuronium bromide (Zemuron)

Phase 3

Anesthesia

Colistimethate sodium (CMS)

Phase 3

Bacterial Infections

Gardasil, human papillomavirus (type 6, 11, 16, 18) recombinant vaccine

Phase 3

Cervical Cancer

ART

Phase 3

HIV-1 Infection

Acarbose

Phase 3

Type 2 Diabetes Mellitus

Pegylated interferon alfa-2b (PegIntron)

Phase 3

Hepatitis B, Chronic (CHB)

Sitagliptin plus metformin

Phase 3

Type 2 Diabetes Mellitus

V110, pneumococcal vaccine polyvalent

Phase 3

Healthy

Linezolid

Phase 3

Pneumonia

Zanzalintinib

Phase 3

Renal Cell Carcinoma

liposomal doxorubicin

Phase 3

Breast Neoplasms

diquafosol tetrasodium (INS365) ophthalmic solution

Phase 3

Dry Eye Disease

Sofosbuvir

Phase 3

Hepatitis C

Intismeran

Phase 3

Non-small Cell Lung Cancer

Fluorouracil (5-FU)

Phase 3

Urinary Bladder Neoplasms

AzaSite

Phase 3

Bacterial Conjunctivitis

rosiglitazone

Phase 3

Type 2 Diabetes Mellitus

Elbasvir/Grazoprevir Fixed Dose Combination

Phase 3

Chronic HCV Infection

VARIVAX™ New Seed Process

Phase 3

Varicella

Reformulated Raltegravir

Phase 3

HIV Infection

Pneumococcal Vaccine, Polyvalent (23-valent)

Phase 3

Pneumococcal Infection

Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine

Phase 3

HPV Infections

levoleucovorin

Phase 3

Esophageal Squamous Cell Carcinoma (ESCC)

2XP HEPTAVAX™-II SC

Phase 3

Hepatitis B

V110

Phase 3

Pneumococcal Infection

RotaTeq (V260)

Phase 3

Prevention of Rotavirus Gastroenteritis in Infants and Children Caused by Serotypes G1, G2, G3, G4, and G9

Cetuximab plus Platinum-based Doublet Chemotherapy

Phase 3

Non-Small Cell Lung Cancer (NSCLC)

Background PAH Therapy

Phase 3

Pulmonary Arterial Hypertension

MK-0524B

Phase 3

Primary Hypercholesterolemia

L-PZQ ODT 50 mg/kg

Phase 3

Schistosomiasis

boceprevir (SCH 503034)

Phase 3

Chronic Hepatitis C

lovastatin

Phase 3

Atherosclerosis

Aprepitant

Phase 3

Post-operative Nausea

DOR

Phase 3

HIV-1 Infection

MMRV (AMP)

Phase 3

Measles

Folinic Acid

Phase 3

Metastatic Colorectal Cancer

Lamivudine

Phase 3

HIV Infections

RotaTeq™ experimental formulation

Phase 3

Rotavirus Gastroenteritis

BIC/FTC/TAF

Phase 3

HIV-1 Infection

Ifinatamab Deruxtecan

Phase 3

Castration-Resistant Prostatic Cancer

denufosol tetrasodium (INS37217) Inhalation Solution

Phase 3

Cystic Fibrosis

Bomedemstat

Phase 3

Thrombocythemia, Essential

Sulfonylurea

Phase 3

Type 2 Diabetes Mellitus

Pembrolizumab (MK-3475)

Phase 3

Merkel Cell Carcinoma

Zidovudine

Phase 3

HIV Infections

MK-0518

Phase 3

HIV Infections

Grazoprevir 100mg / Elbasvir 50 mg FDC

Phase 3

Chronic Hepatitis C Virus

succinylcholine

Phase 3

Neuromuscular Blockade

Kuvan®

Phase 3

Phenylketonuria

Tulisokibart

Phase 3

Hidradenitis Suppurativa

MK-1084

Phase 3

Colon Adenocarcinoma

Pioglitazone hydrochloride

Phase 3

Type 2 Diabetes Mellitus

BCG

Phase 3

Urinary Bladder Neoplasms

Rebif®

Phase 3

Clinically Isolated Syndrome

Zoster Vaccine, Live, (Oka-Merck)

Phase 3

Varicella Virus Infection

peg-IFN

Phase 3

Hepatitis C, Chronic

Grazoprevir 100 mg/Elbasvir 50 mg fixed-dose combination tablets

Phase 3

Chronic Hepatitis C

Zoster Vaccine, Live, (Oka-Merck), ZOSTAVAX™

Phase 3

Herpes Zoster

Sitagliptin 100 mg/simvastatin 40 mg FDC

Phase 3

Type 2 Diabetes Mellitus

Prevnar 13®

Phase 3

Streptococcus Pneumoniae Infection

MK0991, caspofungin acetate / Duration of Treatment:

Phase 3

Fungal Infection

Ertugliflozin 10 mg

Phase 3

Type 2 Diabetes Mellitus

daptomycin

Phase 3

Pneumonia, Bacterial

MK0831

Phase 3

HIV Infections

Frespaciguat

Phase 3

Pulmonary Hypertension

Preservative-Free Tafluprost

Phase 3

Open-angle Glaucoma

Palivizumab

Phase 3

RSV Infection

Ertugliflozin 5 mg

Phase 3

Type 2 Diabetes Mellitus

Rotateq™

Phase 3

Rotavirus Infections

Clesrovimab

Phase 3

Respiratory Syncytial Viruses

ProQuad (Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live)

Phase 3

Measles

alvimopan

Phase 3

Ileus

Filgrastim

Phase 3

Metastatic Non-small Cell Lung Cancer

V503 Vaccine

Phase 3

Papillomavirus Infections

granisetron

Phase 3

Chemotherapy-induced Nausea and Vomiting (CINV)

MK-8527

Phase 3

Human Immunodeficiency Virus (HIV)

PCV15 - Part B

Phase 3

Pneumococcal Disease

luspatercept

Phase 3

B-Thalassemia

Zilovertamab vedotin

Phase 3

B-cell Acute Lymphoblastic Leukemia

Saizen® A

Phase 3

Children Born With Serious Intra-uterine Growth Retardation

Doravirine, Tenofovir, Lamivudine

Phase 3

HIV-1 Infection

Pembrolizumab/Quavonlimab

Phase 3

Colorectal Cancer

MK-5172A

Phase 3

Chronic Hepatitis C

PegIntron (peginterferon alfa-2b; SCH 54031)

Phase 3

Hepatitis

Grazoprevir

Phase 3

Chronic Hepatitis C (CHC)

vinflunine

Phase 3

Urothelial Cancer

PEG-Intron

Phase 3

Hepatitis C

Granulocyte Colony-Stimulating Factor (G-CSF)

Phase 3

DLBCL

MK0217, alendronate sodium / Duration of Treatment: 1 Month

Phase 3

Osteoporosis

Nemtabrutinib

Phase 3

Chronic Lymphocytic Leukemia

Emtricitabine/tenofovir disoproxil (FTC/TDF)

Phase 3

Human Immunodeficiency Virus (HIV)

Zoster Vaccine, Live

Phase 3

Herpes Zoster

Efprezimod alfa

Phase 3

Graft Versus Host Disease

Zoster Vaccine, Live (AMP)

Phase 3

Herpes Zoster

Prevnar 13™

Phase 3

Pneumococcal Infections

Cisplatin/Carboplatin

Phase 3

Carcinoma, Squamous Cell of Head and Neck

Pembrolizumab/Vibostolimab

Phase 3

Lung Neoplasms

Modified Process Hepatitis B Vaccine

Phase 3

Hepatitis B

ProQuad® manufactured with recombinant Human Albumin (rHA)

Phase 3

Measles

Gardasil™

Phase 3

Papillomavirus Infections

Varicella Virus Vaccine Live (Oka-Merck)

Phase 3

Varicella

Fosaprepitant dimeglumine

Phase 3

Chemotherapy-Induced Nausea and Vomiting (CINV)

MK0557

Phase 3

Obesity

V181

Phase 3

Healthy

Aprepitant 125 mg

Phase 3

Chemotherapy Induced Nausea and Vomiting

Human Papillomavirus (HPV) 16 Monovalent

Phase 3

Cervical Cancer

PegIntron

Phase 3

Hepatitis C

Atropine

Phase 3

Anesthesia, General

Glycemic Rescue 1

Phase 3

Diabetes Mellitus

Zoster Vaccine, Live (Zostavax™)

Phase 3

Shingles

DOR/ISL

Phase 3

HIV Infection

Rocuronium bromide (Org 9426)

Phase 3

Muscle Relaxation

Axitinib

Phase 3

Renal Cell Carcinoma

Sitagliptin 100 mg q.d.+ Pioglitazone 45 mg q.d.

Phase 3

Type 2 Diabetes Mellitus

Pembrolizumab Formulated with Berahyaluronidase Alfa

Phase 3

Metastatic Non-small Cell Lung Cancer

Rocuronium 0.6 mg/kg intubating dose

Phase 3

Anesthesia

Androgen Deprivation Therapy (ADT)

Phase 3

Metastatic Hormone-Sensitive Prostate Cancer

Pneumovax™ 23

Phase 3

Pneumococcal Infections

Glimerpiride

Phase 3

Type 2 Diabetes Mellitus

caspofungin acetate

Phase 3

Fungal Infection

Posaconazole

Phase 3

Mycoses

Metformin - Rescue

Phase 3

Diabetes Mellitus, Type 2

Infanrix® hexa

Phase 3

Varicella

Cisplatin (as radiosensitizer)

Phase 3

Endometrial Neoplasms

Rocuronium bolus maintenance

Phase 3

Anesthesia

Vecuronium

Phase 3

Anesthesia, General

IV Tulisokibart

Phase 3

Crohn's Disease

Peginterferon alfa-2b (PEG2b)

Phase 3

Hepatitis C, Chronic

V114

Phase 3

Pneumococcal Infections

Peg-interferon alfa-2b

Phase 3

Hepatitis C, Chronic

Daptomycin 4 mg/kg

Phase 3

Staphylococcal Infection

Gonalef® (Follitropin alfa)

Phase 3

Infertility

peg-Interferon alfa-2a

Phase 3

Hepatitis C, Chronic

Calderasib

Phase 3

Non-small Cell Lung Cancer

ZOSTAVAX

Phase 3

Herpes Zoster

(Gardasil™) human papillomavirus (types 6, 11, 16, 18) recombinant vaccine

Phase 3

Condylomata Acuminata

Peginterferon

Phase 3

Multiple Myeloma

H2 Receptor Antagonist

Phase 3

Non-small Cell Lung Cancer (NSCLC)

RotaTeq®

Phase 3

Meningitis, Meningococcal

sitagliptin phosphate

Phase 3

Type 2 Diabetes

Infliximab

Phase 3

Psoriasis

Boceprevir (BOC)

Phase 3

Chronic Hepatitis C

Intismeran autogene

Phase 3

Bladder Cancer

MK0869, aprepitant

Phase 3

Postoperative Nausea and Vomiting

MK0826, ertapenem sodium / Duration of Treatment - 24 weeks

Phase 3

Foot Infections in Diabetic Patients

Naproxen

Phase 3

Endometriosis-related Pain

Ertugliflozin 15 mg

Phase 3

Type 2 Diabetes Mellitus

Pembrolizumab/Vibostolimab Co-Formulation

Phase 3

Small Cell Lung Carcinoma

Voriconazole

Phase 3

Aspergillosis

Short ragweed pollen allergen extract

Phase 3

Rhinitis, Allergic, Seasonal

MK0803, lovastatin

Phase 3

Hypercholesterolemia

fidaxomicin

Phase 3

Clostridium Difficile-Associated Diarrhea (CDAD)

MK-3475A

Phase 3

Non-small Cell Lung Cancer

Prevenar 13™

Phase 3

Pneumococcal Infections

Trifluridine-Tipiracil

Phase 3

Gastroesophageal Cancer

Rescue medication

Phase 3

Non-Muscle Invasive Bladder Cancer

Tisotumab Vedotin

Phase 3

Cervical Cancer

Metformin IR

Phase 3

Type 2 Diabetes Mellitus

Pembrolizumab (K)

Phase 3

Breast Cancer

losartan potassium

Phase 3

Hypertension

niacin (+) laropiprant

Phase 3

Hypercholesterolemia

TAS-102 (trifluridine and tipiracil)

Phase 3

Colorectal Neoplasms

Diquafosol tetrasodium ophthalmic solution, 2%

Phase 3

Dry Eye Disease

favezelimab/pembrolizumab

Phase 3

Hodgkin Lymphoma

Golimumab

Phase 3

Spondylitis, Ankylosing

zoster vaccine live (ZOSTAVAX™)

Phase 3

Herpes Zoster

TAS-102

Phase 3

Colorectal Cancer

Infliximab + methotrexate (MTX)

Phase 3

Arthritis, Rheumatoid

Montelukast

Phase 3

Asthma

anacetrapib

Phase 3

Coronary Heart Disease (CHD)

Zoster Vaccine Live

Phase 3

Herpes Zoster

Epirubicin

Phase 3

Triple Negative Breast Neoplasms

Enlicitide

Phase 3

Hyperlipidemia

Pergoveris®

Phase 3

Infertility

Meropenem

Phase 3

Healthcare-Associated Pneumonia

Suvorexant Low Dose (LD)

Phase 3

Primary Insomnia

ER niacin/laropiprant

Phase 3

Diabetes Mellitus Type 2

Gefapixant 15 mg BID

Phase 3

Chronic Cough

Standard of Care (SOC)

Phase 3

Solid Tumors

Enalapril

Phase 3

Hypertension

Tedizolid phosphate

Phase 3

Acute Bacterial Skin and Skin Structure Infections

r-hCG

Phase 3

Infertility

Ceftolozane/Tazobactam

Phase 3

Complicated Intra-Abdominal Infection

hMG

Phase 3

Infertility

Grazoprevir + Elbasvir

Phase 3

Hepatitis C Infection

dorzolamide hydrochloride (+) timolol maleate

Phase 3

Glaucoma

Cetuximab + concomitant boost radiotherapy

Phase 3

Squamous Cell Carcinoma of the Head and Neck

rofecoxib

Phase 3

Prostate Cancer

SC golimumab

Phase 3

Arthritis, Rheumatoid

ProQuad®

Phase 3

Measles

Sitagliptin 100 mg

Phase 3

Type 2 Diabetes Mellitus

Voglibose

Phase 3

Diabetes Mellitus, Non-Insulin-Dependent

ER-niacin

Phase 3

Primary Hypercholesterolaemia

MK-1293

Phase 3

Type 1 Diabetes Mellitus

Bisoprolol/Amlodipine (Bisoprolol failed group)

Phase 3

Hypertension

PAR-101/OPT-80

Phase 3

Clostridium Infections

ZOSTAVAX™

Phase 3

Herpes Zoster

cetuximab + cisplatin + vinorelbine

Phase 3

Non Small Cell Lung Cancer (NSCLC)

RotaTeq™, rotavirus vaccine, live, oral, pentavalent

Phase 3

Rotavirus Infections

Quadrivalent Human Papillomavirus (HPV, Types 6, 11, 16, 18) Recombinant Vaccine (Gardasil®)

Phase 3

Papillomavirus Infections

sitagliptin 100 mg q.d./metformin ≥ 1500 mg/day

Phase 3

Type 2 Diabetes Mellitus (T2DM)

ER niacin (+) laropiprant (ERN/LRPT)

Phase 3

Dyslipidemia

Infliximab + methotrexate (IFX + MTX)

Phase 3

Arthritis, Psoriatic

MK0966; Rofecoxib / Duration of Treatment: 156 weeks

Phase 3

Colorectal Adenoma

Rebif New Formulation + prophylactic Ibuprofen

Phase 3

Relapsing Multiple Sclerosis

Imipenem

Phase 3

Bacterial Pneumonia

Vorinostat

Phase 3

Mesothelioma

PPSV23

Phase 3

Pneumococcal Disease

L50/H12.5/A5

Phase 3

Hypertension

Boceprevir

Phase 3

Chronic Hepatitis C Genotype 1

Esmirtazapine

Phase 3

Insomnia

MK0826, /Duration of Treatment : 8 Weeks

Phase 3

Complicated Intra-Abdominal Infections

PNEUMOVAX™23

Phase 3

Pneumococcal Infections

Cetuximab + Platinum (Cisplatin or Carboplatin) + 5Fluorouracil (5-FU)

Phase 3

Head and Neck Cancer

Finasteride

Phase 3

Enlarged Prostate

raltegravir

Phase 3

HIV

MK0826, ertapenem sodium

Phase 3

Infections

sugammadex

Phase 3

Neuromuscular Blockade

hydrochlorothiazide (HCTZ)

Phase 3

Hypertension

pembrolizumab

Phase 3

Colorectal Neoplasms

Ertapenem sodium

Phase 3

Infection; Diabetic Foot

loratadine; montelukast

Phase 3

Rhinitis, Allergic, Seasonal

Recombinant Human Papillomavirus Nonavalent Vaccine

Phase 3

AIDS-Related Human Papillomavirus Infection

Pembrolizumab (+) Berahyaluronidase alfa

Phase 3

Lung Cancer

Tedizolid Phophate

Phase 3

Skin Diseases, Infectious

Isentress®

Phase 3

HIV Infections

MK0826, ertapenem sodium / Duration of Treatment: 14 Days

Phase 3

Infection

MK0507A, dorzolamide hydrochloride (+) timolol maleate

Phase 3

Glaucoma

Sitagliptin

Phase 3

Hyperlipidemia

MK0217A, alendronate sodium (+) cholecalciferol / Duration of Treatment: 24 weeks

Phase 3

Osteoporosis

raltegravir potassium

Phase 3

HIV Infections

Vancomycin (or equivalent)

Phase 3

Acute Hematogenous Osteomyelitis

Insulin

Phase 3

Type 2 Diabetes Mellitus

Ezetimibe

Phase 3

Hypercholesterolemia

RotaTeq™ - Rotavirus Vaccine, Live, Oral, Pentavalent

Phase 3

Vomiting

Calcium supplement

Phase 3

Osteoporosis

pneumococcal 23v polysaccharide vaccine

Phase 3

Pneumococcal Infection

niacin (+) laropiprant (+) simvastatin

Phase 3

Primary Hypercholesterolemia

Modified Process Hepatitis B Vaccine (Experimental)

Phase 3

Hepatitis B

rotavirus vaccine, live, oral, pentavalent

Phase 3

Rotavirus Infections

sitagliptin/metformin

Phase 3

Type 2 Diabetes Mellitus

Grazoprevir/Elbasvir

Phase 3

Hepatitis C

MK-6072

Phase 3

Clostridium Difficile Infection

Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine (GARDASIL™)

Phase 3

Papillomavirus Infections

V212

Phase 3

Herpes Zoster

laropiprant/niacin (MK0524A)

Phase 3

Hypercholesterolemia

Riociguat (Adempas, BAY63-2521)

Phase 3

Hypertension, Pulmonary

9vHPV vaccine

Phase 3

Papillomavirus Infections

Gonal-f®

Phase 3

Assisted Reproductive Techniques

Dexamethasone 4 mg

Phase 3

Non-Small-Cell Lung Carcinoma

COL-1620

Phase 3

Luteal Hormone Supplementation in In-vitro Fertilization

losartan potassium (+) hydrochlorothiazide

Phase 3

Hypertension

V441, diptheria, tetanus, acellular pertussis, inactivated poliomyelitis, hepatitis B (recombinant), & Haemophilus influenza type b conjugate vaccine

Phase 3

Diphtheria

Open-label Metformin

Phase 3

Type 2 Diabetes

Acid Nicotinique

Phase 3

Acute Coronary Syndrome (ACS)

Interferon-alpha2b - 1 year

Phase 3

Melanoma

Pre-treatment with rLH (Luveris 75 IU),

Phase 3

Infertility, Female

Varicella-zoster vaccine

Phase 3

Herpes Zoster

V501

Phase 3

Human

Preladenant

Phase 3

Parkinson Disease

Olaparib

Phase 3

Ovarian Cancer

Lantus™

Phase 3

Type 2 Diabetes Mellitus

Opevesostat

Phase 3

Prostate Cancer Metastatic

FTC/TDF + EFV or LPV/R +T20

Phase 3

HIV Infections

Sotatercept

Phase 3

Pulmonary Arterial Hypertension

Induction dose of (a) infliximab followed by combination of (b) pegylated interferon alfa-2b and (c) ribavirin

Phase 3

Hepatitis C, Chronic

7-valent pneumococcal-CRM197 conjugate vaccine

Phase 3

Otitis Media

budesonide and montelukast

Phase 3

Obstructive Sleep Apnea

Avonex®

Phase 3

Multiple Sclerosis, Relapsing-Remitting

Corifollitropin Alfa

Phase 3

Infertility, Female

Bezlotoxumab

Phase 3

Clostridium Difficile Infection

Metronidazole

Phase 3

Complicated Intra-abdominal Infections

Raptiva

Phase 3

Moderate to Severe Psoriasis

Pembrolizumab 400 mg

Phase 3

Small Cell Lung Cancer

mRNA-1273 Vaccine

Phase 3

Papillomavirus Infections

PCV20

Phase 3

Pneumococcal Infection

Rescue Medications

Phase 3

Cervical Cancer

MTX

Phase 3

Arthritis, Rheumatoid

Elbasvir

Phase 3

Hepatitis C

Etoricoxib

Phase 3

Knee Osteoarthritis

V501, Gardasil, human papillomavirus (type 6, 11, 16, 18) recombinant vaccine

Phase 3

Cervical Cancer

V920 Consistency Lot A

Phase 3

Prevention of Ebola Infection

raltegravir (Isentress)

Phase 3

HIV Infections

week 24

Phase 3

Peripheral Spondyloarthritis

Peginterferon alfa-2a

Phase 3

Hepatitis C, Chronic

9 valent human papillomavirus vaccine (Types 6, 11, 16, 18, 31, 33, 45, 52, 58)

Phase 3

HPV Positive Oropharyngeal Squamous Cell Carcinoma

Letermovir

Phase 3

Cytomegalovirus Infection

Ertugliflozin

Phase 3

Type 2 Diabetes Mellitus

0.9% sodium chloride (NaCl)

Phase 3

Anesthesia

Peginterferon alfa-2b

Phase 3

Carcinoma, Hepatocellular

V232 Modified Process Hepatitis B Vaccine: Lot A

Phase 3

Hepatitis B Infection

Ipragliflozin

Phase 3

Type 2 Diabetes Mellitus

PCV13

Phase 3

Pneumococcal Infections

Rocuronium bromide

Phase 3

Anesthesia

IMI/REL

Phase 3

Suspected or Documented Gram-negative Bacterial Infection

INFANRIX™ hexa

Phase 3

Bacterial Infections

Letermovir 480 mg once daily

Phase 3

Kidney Transplant; Complications

PR5I

Phase 3

Neisseria Meningitidis

Varicella Virus Vaccine Live (2007 Process) (Oka/Merck)

Phase 3

Varicella

Anacetrapib 100 mg

Phase 3

Hypercholesterolemia

MK0966, rofecoxib

Phase 3

Postoperative Pain

Cladribine (MAVENCLAD®)

Phase 3

Advanced Multiple Sclerosis

Posaconazole oral suspension

Phase 3

Mycoses

Tobramycin

Phase 3

Bacterial Conjunctivitis

Delstrigo

Phase 3

HIV-1-infection

ezetimibe with simvastatin

Phase 3

Hypercholesterolemia

Pegylated interferon alfa-2b

Phase 3

Hepatitis C

Follitropin alfa liquid formulation

Phase 3

Infertility

Gliclazide

Phase 3

Type 2 Diabetes Mellitus

Micronised Progesterone

Phase 3

Infertility

Imipenem+Cilastatin/Relebactam

Phase 3

Complicated Intra-abdominal Infection

MK-0524A

Phase 3

Hypercholesteremia

Basal Insulin

Phase 3

Type 2 Diabetes Mellitus

Ezetimibe + Atorvastatin

Phase 3

Hypercholesterolemia

Supportive care measures

Phase 3

Non-small Cell Lung Cancer (NSCLC)

Golimumab 50 mg SC

Phase 3

Arthritis

sac-TMT

Phase 3

Non-small Cell Lung Cancer

Grazoprevir 100 mg/Elbasvir 50 mg FDC tablet (MK-5172A)

Phase 3

Chronic Hepatitis C

Org 50081

Phase 3

Insomnia

ezetimibe (plus simvastatin)

Phase 3

Atherosclerosis

Doravirine

Phase 3

HIV-1

Telcagepant

Phase 3

Migraine

Epacadostat

Phase 3

Gastric Adenocarcinoma

rolofylline

Phase 3

Heart Failure, Congestive

ZOSTAVAX™ (concomitant)

Phase 3

Herpes Zoster

HBVAXPRO™

Phase 3

Hepatitis B

VARIVAX™

Phase 3

Varicella

Lenvatinib

Phase 3

Non-small Cell Lung Cancer

SC Tulisokibart

Phase 3

Ulcerative Colitis

V503 (9-valent Human Papillomavirus [HPV] L1 Virus-Like Particle [VLP] vaccine)

Phase 3

Human Papillomavirus Infection

Estrogens

Phase 3

Infertility

V116

Phase 3

Pneumococcal Infection

Omarigliptin

Phase 3

Type 2 Diabetes Mellitus

Vericiguat

Phase 3

Heart Failure

MR Prednisone

Phase 3

Rheumatoid Arthritis

DAPTACEL™

Phase 3

Bacterial Infections

Pembrolizumab 200 mg

Phase 3

Non-Small-Cell Lung Carcinoma

Enpatoran

Phase 3

Systemic Lupus Erythematosus (SLE)

V260

Phase 3

Rotavirus Gastroenteritis

IMI/REL FDC

Phase 3

Hospital-Acquired Bacterial Pneumonia

MK0974 50 mg

Phase 3

Migraine

sitagliptin 100 mg q.d./pioglitazone 30 mg q.d

Phase 3

Type 2 Diabetes Mellitus

Combination of (a) pegylated interferon alfa-2b and (b) rebetol

Phase 3

Liver Transplantation

Gefapixant 45 mg twice daily (BID)

Phase 3

Chronic Cough

Patritumab Deruxtecan

Phase 3

Malignant Neoplasm

Epinephrine

Phase 3

Malignant Neoplasms of Male Genital Organs

Vicriviroc

Phase 3

HIV Infections

Simvastatin 20 mg daily

Phase 3

Cardiovascular Disease

alendronate with cholecalciferol

Phase 3

Osteoporosis

MK-8748

Phase 3

Diabetic Retinopathy

Molnupiravir

Phase 3

Coronavirus Disease (COVID-19)

Gefapixant

Phase 3

Chronic Cough

ertapenem sodium (MK0826)

Phase 3

Urinary Tract Infection

Pegylated liposomal doxorubicin (SCH 200746)

Phase 3

Breast Cancer

peginterferon alfa-2b (SCH 54031)

Phase 3

Chronic Hepatitis C

Pembrolizumab SC

Phase 3

Non-Small Cell Lung Cancer

MK0869, aprepitant / Duration of Treatment: 3 days

Phase 3

Nausea

ISL

Phase 3

Human Immunodeficiency Virus Type 1 (HIV-1) Infection

Indinavir sulfate

Phase 3

HIV Infections

TR-701 FA

Phase 3

Skin and Subcutaneous Tissue Bacterial Infections

Ridaforolimus

Phase 3

Sarcoma

V503

Phase 3

Papillomavirus Infections

Gardasil

Phase 3

Papillomavirus Infections

Neostigmine

Phase 3

Anesthesia

5-Fluorouracil

Phase 3

Uterine Cervical Neoplasms

CB-183,315

Phase 3

Clostridium Difficile Infection

Saizen®

Phase 3

Fibromyalgia

Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live

Phase 3

Measles

ceftriaxone sodium

Phase 3

Infection

PCV15

Phase 3

Pneumonia, Pneumococcal

mFOLFOX6

Phase 3

Colorectal Carcinoma

eribulin

Phase 3

Metastatic Triple Negative Breast Cancer

Sitagliptin (MK0431)

Phase 3

Diabetes Mellitus, Type II

Sitagliptin 50 mg

Phase 3

Type 2 Diabetes Mellitus

Cisplatin 100 mg/m^2

Phase 3

Head and Neck Neoplasms

Efavirenz

Phase 3

HIV Infections

Enlicitide Decanoate

Phase 3

Hypercholesterolemia

Odanacatib

Phase 3

Osteoporosis Postmenopausal

pegylated interferon alpha-2b

Phase 3

Hepatitis B, Chronic

neostigmine and glycopyrrolate or atropine

Phase 3

Neuromuscular Blockade

Preservative-Free Tafluprost or vehicle

Phase 3

Glaucoma

Preladenant 2 mg tablet

Phase 3

Parkinson Disease

V419

Phase 3

Bacterial Infections

Suvorexant

Phase 3

Insomnia

Recombinant human luteinizing hormone (r-hLH)

Phase 3

Hypogonadism

Rocuronium

Phase 3

Anesthesia, General

Experimental: V503

Phase 3

Cervical Cancer

vaniprevir

Phase 3

Hepatitis C, Chronic

Peginterferon alfa-2b (PegIntron, SCH 54031)

Phase 3

Hepatitis D, Chronic

RNF

Phase 3

Multiple Sclerosis

H1 receptor antagonist

Phase 3

Ovarian Cancer

V501, Gardasil, human papillomavirus (type 6, 11, 16, 18) recombinant vaccine / Duration of Treatment: 4 years

Phase 3

Cervical Cancer

Telcagepant potassium 150 mg

Phase 3

Migraine

Cetrorelix acetate

Phase 3

Polycystic Ovarian Syndrome

Hepatitis A Vaccine, Purified Inactivated (VAQTA™)

Phase 3

Hepatitis A Virus Infection

Pegylated interferon alfa-2b (SCH 54031)

Phase 3

Hepatitis C, Chronic

Sugammadex 0.5 mg/kg

Phase 3

Anesthesia

VARIVAX® PE34 Process

Phase 3

Varicella

INS365 Ophthalmic Solution

Phase 3

Keratoconjunctivitis Sicca

Rotavirus vaccine

Phase 3

Bacterial Infections

MK-8591A

Phase 3

HIV-1 Infection

Belzutifan

Phase 3

Renal Cell Carcinoma

Interferon-beta-1a

Phase 3

Hepatitis C

Dinaciclib

Phase 3

Chronic Lymphocytic Leukemia (CLL)

Vorapaxar 2.5 mg

Phase 3

Cerebral Infarction

Rocurium

Phase 3

Anesthesia, General

Vericiguat tablet

Phase 3

Heart Failure

ATRIPLA™

Phase 3

Human Immunodeficiency Virus (HIV)

MK-1045

Phase 3

Lymphoma, Non-Hodgkin

Glipizide

Phase 3

Diabetes Mellitus, Type 2

Surotomycin

Phase 3

Clostridium Difficile Infection

Blinatumomab

Phase 3

B-cell Acute Lymphoblastic Leukemia

Anagrelide

Phase 3

Essential Thrombocythemia

Emtricitabine (FTC)/Tenofovir Disoproxil (TDF)

Phase 2

Primary Biliary Cholangitis

Arm A: Pemetrexed Cisplatin

Phase 2

Non Small Cell Lung Cancer

EVX-01

Phase 2

Melanoma Stage IV

PembroRT

Phase 2

Non-small Cell Lung Cancer, NSCLC

Brexucabtagene autoleucel ( other names: brexu-cel , Tecartus)

Phase 2

Recurrent Mantle Cell Lymphoma

MK1903

Phase 2

Dyslipidemia

MK-2206

Phase 2

PANCREAS

Peginterferon alfa-2a (Peg-IFN)

Phase 2

Hepatitis C, Chronic

denufosol tetrasodium Inhalation Solution

Phase 2

Cystic Fibrosis

CXA-101

Phase 2

Complicated Urinary Tract Infection

MK0524A, niacin (+) laropiprant / Duration of Treatment : 4 Weeks

Phase 2

Hypercholesterolemia

pegylated interferon

Phase 2

Chronic Hepatitis C

Multiple low dose cyclophosphamide

Phase 2

Multiple Myeloma

Azacitadine

Phase 2

Acute Myeloid Leukemia

Cisplatin (TP)

Phase 2

Squamous Cell Carcinoma of the Hypopharynx

pIL-12

Phase 2

Melanoma

LNS8801 -Small molecule, orally bioavailable, selective agonist of GPER

Phase 2

Solid Tumor, Adult

LY3537982

Phase 2

Carcinoma, Non-Small-Cell Lung

Butantan - DV

Phase 2

Dengue

denufosol tetrasodium (INS37217)

Phase 2

Cystic Fibrosis

OPT-80

Phase 2

Diarrhea

Dalotuzumab

Phase 2

Carcinoma, Non-small-cell Lung

MK-8777

Phase 2

Depression

ARQ 197

Phase 2

Pancreatic Neoplasms

ARQ 501

Phase 2

Cancer

Robatumumab

Phase 2

Colorectal Cancer

ADL5945 0.1 mg

Phase 2

Opioid Induced Constipation

MK0431, sitagliptin phosphate / Duration of Treatment: 21 Weeks

Phase 2

Diabetes Mellitus, Type II

M5717 330 mg

Phase 2

Acute Malaria

Vibostolimab

Phase 2

Melanoma

MK0493

Phase 2

Obesity

MK0812 / Duration of Treatment: 12 Weeks

Phase 2

Arthritis, Rheumatoid

INS37217 Nasal Spray

Phase 2

Perennial Allergic Rhinitis

MK0777

Phase 2

Generalized Anxiety Disorder

Uprifosbuvir

Phase 2

Hepatitis C

Pneumococcal Conjugate Vaccine (V114)

Phase 2

Pneumococcal Infections

V114 Aluminum-adjuvanted

Phase 2

Pneumococcal Infections

Vibostolimab/Pembrolizumab

Phase 2

Carcinoma, Renal Cell

MK-3120

Phase 2

Urothelial Carcinoma

MK0431, sitagliptin phosphate / Duration of Treatment: 12 Weeks

Phase 2

Type 2 Diabetes Mellitus

Navarixin

Phase 2

Solid Tumors

Daptomycin for Injection

Phase 2

Bacteremia

UFOX + Cetuximab

Phase 2

Previously Untreated Metastatic Colorectal Cancer

Ritonavir

Phase 2

HIV Infections

Raludotatug Deruxtecan (R-DXd)

Phase 2

Gastrointestinal Cancer

Tepotinib

Phase 2

Non-small Cell Lung Cancer

MK-3795

Phase 2

VHL Gene Mutation

V114 Lot 1

Phase 2

Pneumococcal Infections

adavosertib

Phase 2

Ovarian Cancer

MK0249

Phase 2

Attention-Deficit/Hyperactivity Disorder (ADHD)

MK-8435 (Org 25935) 4-8 mg

Phase 2

Schizophrenia

MK-6096

Phase 2

Migraine

Pembrolizumab/vibostolimab coformulation

Phase 2

Bladder Cancer

irinotecan hydrochloride

Phase 2

Metastatic Colorectal Cancer

MK-0941

Phase 2

Type 2 Diabetes Mellitus

Vaniprevir 600 mg b.i.d.

Phase 2

Hepatitis C, Chronic

IDX719

Phase 2

Hepatitis C, Chronic

MK2295

Phase 2

Pain, Postoperative

Quavonlimab

Phase 2

Advanced Solid Tumors

MK-1167

Phase 2

Alzheimer Disease

SCH 530348

Phase 2

Arterial Obstructive Diseases

Epinastine Nasal Spray

Phase 2

Seasonal Allergic Rhinitis

Merck L-830982

Phase 2

Schizophrenia

Avelumab

Phase 2

Squamous Non-Small Cell Lung Cancer

MK-4830

Phase 2

Carcinoma, Non-Small-Cell Lung

zoster vaccine live (Oka/Merck)

Phase 2

Shingles

Raludotatug Deruxtecan

Phase 2

Ovarian Cancer Recurrent

Coformulation favezelimab/pembrolizumab

Phase 2

Esophageal Squamous Cell Carcinoma (ESCC)

Fosaprepitant

Phase 2

Chemotherapy-induced Nausea and Vomiting

Gefapixant 45 mg

Phase 2

Chronic Cough

Farnesyl Protein Transferase Inhibitor

Phase 2

Leukemia

ADL5859

Phase 2

Peripheral Neuropathy

MK2461

Phase 2

Neoplasm

MK0991, caspofungin acetate

Phase 2

Aspergillosis

SCH 486757

Phase 2

Cough

Tecemotide (L-BLP25)

Phase 2

Lung Neoplasms

measles, mumps, and rubella virus vaccine live

Phase 2

Measles

AS900672-Enriched 50 microgram (mcg)

Phase 2

Infertility

Cilengitide

Phase 2

Carcinoma, Non-Small-Cell Lung

ecallantide

Phase 2

Bloodloss

Pembrolizumab (neoadjuvant)

Phase 2

Lung Neoplasm Malignant

MK0518

Phase 2

HIV Infections

ADL5945 0.25 mg

Phase 2

Constipation

ENB003

Phase 2

Cancer

MK-5684

Phase 2

Malignant Neoplasm

Attenuvax

Phase 2

HIV Infections

TU2218 + KEYTRUDA® (Pembrolizumab)

Phase 2

Solid Tumor

Ertugliflozin 1 mg

Phase 2

Diabetes Mellitus, Type 2

M5049 low dose

Phase 2

Systemic Lupus Erythematosus

Pegylated Interferon Alfa

Phase 2

Chronic Hepatitis C

KW-3902IV

Phase 2

Heart Failure, Congestive

Favezelimab

Phase 2

Advanced Non-Small Cell Lung Cancer

tildrakizumab

Phase 2

Psoriasis

SCH 900538

Phase 2

Seasonal Allergic Rhinitis

EBR/GZR FDC Tablet

Phase 2

HCV Infection

MK0916

Phase 2

Diabetes Mellitus, Type 2

V160

Phase 2

Cytomegalovirus (CMV) Infections

MK-2140 (zilovertamab vedotin)

Phase 2

Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Cabazitaxel

Phase 2

Prostatic Neoplasms, Castration-Resistant

L-dopa

Phase 2

Parkinson Disease

MK0364

Phase 2

Obesity

Single low dose cyclophosphamide

Phase 2

Carcinoma, Non-Small-Cell Lung

MK-8189

Phase 2

Schizophrenia, Acute Episode

Recombinant human growth hormone (r-hGH)

Phase 2

Hypochondroplasia

CyPep-1

Phase 2

Advanced Head and Neck Squamous Cell Carcinoma

Stavudine

Phase 2

HIV Infections

Pembrolizumab and Lenvatinib

Phase 2

Hepatocellular Carcinoma

Boserolimab

Phase 2

Small Cell Lung Cancer

2 NRTIs

Phase 2

Human Immunodeficiency Virus (HIV) Infection

PegIFN-2b

Phase 2

HIV Infections

PegIntron (peginterferon alfa-2b)

Phase 2

Hepatitis C, Chronic

Relebactam 250 mg

Phase 2

Intra-abdominal Infections

Atorvastatin/niacin extended-release

Phase 2

Carotid Atherosclerosis

Rebif

Phase 2

Multiple Sclerosis

MK-0873

Phase 2

Rheumatoid Arthritis

Matuzumab

Phase 2

Esophageal Cancer

V504

Phase 2

Cervical Cancer

imipenem/cilastatin 500 mg

Phase 2

Urinary Tract Infections

cetuximab, cisplatin

Phase 2

Breast Neoplasm

Interferon beta-1a

Phase 2

Alzheimer's Disease

V114 Medium Dose

Phase 2

Pneumococcal Infections

V181 High-Potency Level

Phase 2

Dengue Disease

cyclophosphamide (CPA)

Phase 2

Rectal Cancer

Biltricide (racemate praziquantel) oral tablets

Phase 2

Schistosomiasis

Emfilermin, recombinant human leukemia inhibitory factor (r-hLIF)

Phase 2

Infertility Implantation Failure

SCH 900636

Phase 2

Depressive Disorders

Pegylated Lyposomal Doxorubicin

Phase 2

Breast Neoplasm

MK0782

Phase 2

Stomach Ulcer

EMD 525797 250 mg

Phase 2

Metastatic Colorectal Cancer

TR701 FA

Phase 2

Major Cutaneous Abscess

Doravirine, Tenofovir, Lamivudine - Blinded

Phase 2

HIV-1

V940

Phase 2

Squamous Non-small Cell Lung Cancer

R-DXD

Phase 2

Lung Neoplasm

Efinopegdutide

Phase 2

Metabolic Dysfunction-Associated Steatotic Liver Disease

PRA023 IV

Phase 2

Crohn Disease

Zolinza (vorinostat)

Phase 2

Lymphoma

Metolazone

Phase 2

Heart Failure

Suvorexant 20 mg

Phase 2

Delirium in Old Age

ST-067

Phase 2

Cancer

Miransertib

Phase 2

PIK3CA-Related Overgrowth Spectrum (PROS)/Proteus Syndrome (PS)

MK-0893

Phase 2

Diabetes Mellitus, Type 2

ZA

Phase 2

Breast Cancer

L-756423

Phase 2

HIV Infections

timolol/dorzolamide combination

Phase 2

Glaucoma

AO-176

Phase 2

Solid Tumor

Esmeron®

Phase 2

Neuromuscular Blockade

NM283 plus Peg-IFNα-2a

Phase 2

Chronic Hepatitis C

Gefapixant 50 mg

Phase 2

Asthma

MK-2060

Phase 2

End-Stage Renal Disease

IDX184

Phase 2

Chronic Hepatitis C Infection

Pleconaril

Phase 2

Asthma

KVA12123 - Dose Escalation

Phase 2

Cancer

Gocatamig

Phase 2

Small-Cell Lung Cancer

MK-1200

Phase 2

Advanced Solid Tumors

SCH 727965

Phase 2

Breast Neoplasms

V114-A

Phase 2

Pneumococcal Infections

IFN beta 1a 44 mcg TIW

Phase 2

Multiple Sclerosis

Pegylated Liposomal Doxorubicin

Phase 2

Breast Neoplasm

Tepotinib 300 mg

Phase 2

Carcinoma, Hepatocellular

Lenvatinib Capsules

Phase 2

Hepatocellular Carcinoma

Avastin

Phase 2

High-grade Serous Ovarian Carcinoma

Atacicept

Phase 2

Rheumatoid Arthritis

Vibegron

Phase 2

Urinary Bladder, Overactive

Org 34517

Phase 2

Depression

MK-1029

Phase 2

Asthma

Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate

Phase 2

HIV-1 Infection

CRS-207

Phase 2

Metastatic Pancreatic Adenocarcinoma

Lenvatinib Oral Product

Phase 2

Merkel Cell Carcinoma

Coformulated favezelimab/pembrolizumab

Phase 2

Metastatic Urothelial Carcinoma

val-mCyd

Phase 2

Chronic Hepatitis C

Gefapixant 100 mg

Phase 2

Refractory Chronic Cough

Radium-223

Phase 2

Prostate Cancer

Vicriviroc 30 mg

Phase 2

HIV Infections

valopicitabine

Phase 2

Chronic Hepatitis C

MK0677

Phase 2

Alzheimer's Disease

Interferon-beta-1a, 44 microgram

Phase 2

Ulcerative Colitis

MK0991, caspofungin acetate/Duration of Treatment: variable

Phase 2

Candidiasis

TRUVADA®

Phase 2

HIV Infections

Antihistamine

Phase 2

Esophageal Squamous Cell Carcinoma

Oral testosterone undecanoate (Andriol)

Phase 2

Hypogonadism

Dalantercept

Phase 2

Squamous Cell Carcinoma of the Head and Neck

Sugar Pill

Phase 2

Osteoarthritis of the Knee

Sotatercept 0.3 mg/kg

Phase 2

Hypertension, Pulmonary

Vorapaxar

Phase 2

Atherosclerosis

Docetetaxel

Phase 2

Carcinoma, Non-Small-Cell Lung

Pertuzumab

Phase 2

Breast Neoplasms

epinastine 0.1%

Phase 2

Allergic Rhinitis

MK-8998

Phase 2

Schizophrenia

ATX-MS-1467

Phase 2

Multiple Sclerosis

Dalantercept plus sorafenib

Phase 2

Advanced Adult Hepatocellular Carcinoma

Nelfinavir mesylate

Phase 2

HIV Infections

AR51 (12, 10)

Phase 2

Bacterial Infections; Virus Diseases

EV

Phase 2

Bladder Cancer

MK0974

Phase 2

Migraine

diphenhydramine

Phase 2

Carcinoma, Non-Small-Cell Lung

MK-8616

Phase 2

Neuromuscular Blockade

Pembrolizumab 25 MG/ML [KEYTRUDA®]

Phase 2

Advanced Solid Tumor Malignancy

Benznidazole

Phase 2

Chagas Disease

FF-10832

Phase 2

Advanced Urothelial Carcinoma

raltegravir and etravirine

Phase 2

HIV-1 Infection

Ertugliflozin 25 mg

Phase 2

Diabetes Mellitus, Type 2

MK8141

Phase 2

Hypertension

MK0822A

Phase 2

Vitamin D Deficiency

MK0633

Phase 2

Atherosclerosis

MK633

Phase 2

Chronic Obstructive Pulmonary Disease (COPD)

Doxorubicin hydrochloride

Phase 2

Breast Neoplasms

r-FSH

Phase 2

Ovarian Stimulation

Enclitide Chloride

Phase 2

Hypercholesterolemia

Pimicotinib

Phase 2

Tenosynovial Giant Cell Tumor

coformulation pembrolizumab/quavonlimab

Phase 2

Small Cell Lung Carcinoma

ATRA

Phase 2

Melanoma

MK-2214

Phase 2

Early Alzheimer's Disease

Dabrafenib

Phase 2

Melanoma

MK0524A, niacin (+) laropiprant / Duration of Treatment: 17 Weeks

Phase 2

Flushing

ridaforolimus (MK8669)

Phase 2

Prostate Cancer

MK0683, vorinostat, Suberoylanilide Hydroxamic Acid (SAHA) / Duration of Treatment 6 Months

Phase 2

B-cell Lymphoma

Rolapitant Dose 1

Phase 2

Postoperative Nausea and Vomiting

MK0359

Phase 2

Pulmonary Disease, Chronic Obstructive

MK0524

Phase 2

Seasonal Allergies

peginterferon alfa 2b

Phase 2

Hepatitis C, Chronic

TS-1

Phase 2

Gastric Cancer

Rescue

Phase 2

Type II Diabetes Mellitus

Tivantinib

Phase 2

Advanced Solid Tumors

Recombinant human follicle stimulating hormone (r-hFSH)

Phase 2

Infertility

Itraconazole

Phase 2

Chronic Hepatitis C

Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine (V501)

Phase 2

HPV Infections

Pegylated Interferon (peg-IFN)

Phase 2

Hepatitis C

Ifinatamab Deruxtecan (I-DXd)

Phase 2

Small Cell Lung Cancer

Ruzasvir

Phase 2

Hepatitis C

Letermovir oral granules

Phase 2

Cytomegalovirus (CMV) Infection

Raltegravir Film-coated Tablet

Phase 2

HIV Infection

teicoplanin

Phase 2

Osteomyelitis

SCH 900271 15mg

Phase 2

Primary Hypercholesterolemia

MK5757

Phase 2

Schizophrenia

Samatasvir

Phase 2

Chronic Hepatitis C Virus

Ulevostinag

Phase 2

Head and Neck Squamous Cell Carcinoma (HNSCC)

ARQ 501 in combination with gemcitabine

Phase 2

Pancreatic Cancer

V205C, measles, mumps, and rubella virus vaccine live

Phase 2

Measles

medroxyprogesterone acetate tablets OR megestrol acetate

Phase 2

Endometrial Cancer

Posaconazole IV 6 mg/kg

Phase 2

Invasive Fungal Infection

Islatravir

Phase 2

HIV-1 Infection

RSV A Memphis 37b

Phase 2

Respiratory Syncytial Virus

SCH 619734

Phase 2

Cough

ADL5747

Phase 2

Osteoarthritis of the Knee

TR-701 200 mg

Phase 2

Skin Diseases, Infectious

Efinopegdutide 20 mg/mL

Phase 2

Nonalcoholic Fatty Liver Disease

Sitagliptin 25 mg

Phase 2

Glucose Intolerance

ADL5859 30 mg

Phase 2

Acute Pain

MK3207- 2.5 mg

Phase 2

Migraine

Grazoprevir (GZR)

Phase 2

Hepatitis C Virus

I-DXd

Phase 2

Esophageal Squamous Cell Carcinoma

SCH 56592

Phase 2

Onychomycosis

MK0524A, /Duration of Treatment : 8 Weeks

Phase 2

Flushing

Grazoprevir/Elbasvir FDC

Phase 2

Hepatitis C

MK-5442

Phase 2

Osteoporosis

Caspofungin

Phase 2

Candidiasis, Esophageal

M5717 60 mg

Phase 2

Malaria Infection

SCH 497079

Phase 2

Obesity

tretinoin

Phase 2

Acute Myeloid Leukemia

MK0826, ertapenem sodium /Duration of Treatment: 14 Days

Phase 2

Urinary Tract Infections

MK-0482

Phase 2

Carcinoma, Non-Small-Cell Lung

MK0736

Phase 2

Hypertension

Quadrivalent HPV (Types 6,11,16,18) L1 VLP Vaccine 20/40/40/20

Phase 2

Papillomavirus Infections

MK0686

Phase 2

Pain, Postoperative

MK-6213

Phase 2

Hypercholesterolemia

VigantOL oil plus interferon beta-1a (Rebif)

Phase 2

Relapsing-Remitting Multiple Sclerosis

Vicriviroc maleate

Phase 2

HIV

MK-8690

Phase 2

Colitis Ulcerative

Olaparib 400 mg

Phase 2

Metastatic Castration-Resistant Prostate Cancer

MK0429

Phase 2

Post-Menopausal Osteoporosis

Letermovir Pill

Phase 2

CMV

Ensifentrine

Phase 2

COPD

MK-0634 50 mg

Phase 2

Urinary Incontinence

ridaforolimus + dalotuzumab

Phase 2

Breast Cancer

rolofyline

Phase 2

Congestive Heart Failure

Posaconazole IV

Phase 2

Invasive Aspergillosis

MK-1029 150 mg

Phase 2

Asthma

r-hFSH

Phase 2

Infertility

Cilengitide 2000 mg once weekly

Phase 2

Squamous Cell Cancer

Navarixin 10 mg

Phase 2

Psoriasis

MK0639, indinavir sulfate / Duration of Treatment: 48 Weeks

Phase 2

HIV Infections

PR51 (3, 10)

Phase 2

Bacterial Infections; Virus Diseases

carboplatin AUC of 6, paclitaxel 175 mg/m2, and pembrolizumab 200 mg, i.v. on day 1, every 21 days for 3 cycles

Phase 2

Squamous Cell Carcinoma of Larynx

Methotrexate 1 GM Injection

Phase 2

Gestational Trophoblastic Neoplasias (GTN)

TEW-7197

Phase 2

Metastatic Colorectal Cancer

M9140

Phase 2

Solid Tumors

Imprime PGG

Phase 2

Malignant Neoplasm of Breast

Crinone 8%

Phase 2

Postmenopausal Endometrium

Mirdametinib

Phase 2

Central Nervous System Tumors

Bintrafusp Alfa

Phase 2

Nasopharyngeal Carcinoma

Pembrolizumab (Keytruda)

Phase 2

Thyroid Cancer

Axatilimab

Phase 2

TNBC - Triple-Negative Breast Cancer

Alendronate

Phase 2

Osteoporosis

Nirogacestat

Phase 2

Tumor

Boceprevir, Peg-interferon alfa 2b and Ribavirin

Phase 2

HCV Coinfection

Peg-Interferon α-2b or Peg-Interferon α-2a

Phase 2

HCV Infection

Pembrolizumab Injection [Keytruda]

Phase 2

Malignant Neoplasm of Breast

ATG-022

Phase 2

Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

ART Intensification

Phase 2

HIV-1 Infection

Allogeneic cytomegalovirus-specific T cells

Phase 2

Glioblastoma Multiforme

ADV/HSV-tk

Phase 2

Metastatic Non-small Cell Lung Cancer

Testosterone Enanthate

Phase 2

Male Hypogonadism

BET Bromodomain Inhibitor ZEN-3694

Phase 2

Castration-Resistant Prostate Carcinoma

olaparibp, embro

Phase 2

Ovarian Cancer

aprepitant, ondansetron, dexamethasone

Phase 2

Nausea

azacytidine

Phase 2

Lymphoma

galinpepimut-S

Phase 2

Acute Myelogenous Leukemia

Neoadjuvant Pembrolizumab

Phase 2

Breast Cancer

Entereg

Phase 2

Laparoscopic Colonic Resection

D-1553

Phase 2

Solid Tumor, Adult

Bilastine

Phase 2

Seasonal Allergic Rhinitis

Q901

Phase 2

Advanced Cancer

5HT3

Phase 2

Chemotherapy-Induced Nausea and Vomiting

FOLFIRI + Cetuximab

Phase 2

Metastatic Colorectal Cancer

Prednisone 5Mg

Phase 2

Prostate Cancer Aggressiveness

GVAX Pancreatic Cancer Vaccine

Phase 2

Pancreatic Cancer

Lenvatinib Mesylate

Phase 2

Kidney Cancer

Polatuzumab vedotin

Phase 2

Lymphoma, Large B-Cell, Diffuse

IMGN853

Phase 2

Endometrial Cancer

GAd-209-FSP low dose

Phase 2

Solid Tumor, Adult

Peptide Receptor Radionuclide Therapy (PRRT) using 177Lu-DOTA0-Tyr3-Octreotate

Phase 2

Metastatic Malignant Neoplasm in the Liver

Vinblastine

Phase 2

Classical Hodgkin Lymphoma

Defactinib

Phase 2

Resectable Pancreatic Ductal Adenocarcinoma (PDAC)

ACE-536

Phase 2

Beta-Thalassemia

Paclitaxel 45 mg/m^2

Phase 2

Non-small Cell Lung Cancer

Pembrolizuma

Phase 2

Metastatic Breast Cancer

Vorinostat Velcade Dexamethasone

Phase 2

Multiple Myeloma

Pembrolizumab with All-Trans Retinoic Acid

Phase 2

Stage IV Melanoma

Elpipodect

Phase 2

Schizophrenia

CXA-101/ tazobactam and metronidazole

Phase 2

Complicated Intra-abdominal Infection

ABL103

Phase 2

Solid Tumors

pembrolizumab, gemcitabine and cisplatin

Phase 2

Bladder Cancer

Ezetimibe/Simvastatin

Phase 2

Type 1 Diabetes Mellitus

R-CHOP Protocol

Phase 2

B Cell Lymphoma

MK-3475 (neoadjuvant)

Phase 2

Cancer of Head and Neck

Bemcentinib

Phase 2

Lung Cancer Metastatic

Pembrolizumab 200 mg IV infusion

Phase 2

Stage IIIB(N2) Non-small Cell Lung Cancer

Poly-ICLC

Phase 2

Metastatic Colon Cancer

Pegylated Interferon alpha 2b

Phase 2

HIV-1 Infection

UFT

Phase 2

Metastatic Colorectal Cancer

Vinblastine Sulfate

Phase 2

Stage II Bladder Cancer AJCC v8

DPX-Survivac

Phase 2

Relapsed Diffuse Large B-cell Lymphoma

Bacillus Calmette-Guérin (BCG)

Phase 2

Bladder Cancer

HIF-2alpha Inhibitor PT2385

Phase 2

Recurrent Glioblastoma

pTVG-HP

Phase 2

Castration-resistant Prostate Cancer

emtricitabine / tenofovir disoproxil fumarate / raltegravir .

Phase 2

HIV-2 Infection

GSK2636771

Phase 2

Melanoma and Other Malignant Neoplasms of Skin

Human Papillomavirus vaccine

Phase 2

Cervical High Grade Squamous Intraepithelial Lesion

Tinodasertib

Phase 2

Metastatic Colorectal Cancer

Azithromycin ophthalmic solution, 1%

Phase 2

Blepharitis

Aprepitant/Ramosetron/Dexamethasone

Phase 2

Chemotherapy-Induced Nausea and Vomiting

Zepatier

Phase 2

End Stage Renal Disease

Prednisone or prednisolone

Phase 2

Metastatic Castration-resistant Prostate Cancer

Sitagliptin + Metformin

Phase 2

Pre-diabetes

ACP-196 in combination with pembrolizumab

Phase 2

Metastatic Urothelial Carcinoma

Letermovir 480 MG [Prevymis]

Phase 2

Cytomegalovirus Infections

Cefepime

Phase 2

Other Infectious Diseases

Pegzilarginase

Phase 2

Small-cell Lung Cancer

Spevatamig (PT886)

Phase 2

Gastric or Gastroesophageal Junction Adenocarcinoma

Pembrolizumab 25 MG/1 ML Intravenous Solution

Phase 2

Metastatic Uveal Melanoma

MK-1775 and carboplatin

Phase 2

Epithelial Ovarian Cancer

EIDD-2801

Phase 2

SARS-CoV 2

Gemox, Cetuximab

Phase 2

Advanced Biliary Cancer

Encorafenib Oral Capsule + Cetuximab

Phase 2

Colorectal Cancer

cetuximab, cisplatin, capecitabine

Phase 2

Gastric Cancer

Epclusa

Phase 2

Lung Diseases

acetominophen

Phase 2

Migraine

FLOT

Phase 2

Esophagogastric Adenocarcinoma

Afatinib

Phase 2

Carcinoma, Non-Small-Cell Lung

Hyperpolarized 13C-Pyruvate

Phase 2

Neuroendocrine Tumors

Cyklokapron(R)

Phase 2

Bloodloss

IMG-7289

Phase 2

Thrombocythemia, Essential

cis/carboplatin and etoposide

Phase 2

Small Cell Lung Cancer (SCLC)

Recombinant Vesicular Stomatitis Vaccine for Ebola (rVSV∆G-ZEBOV-GP)

Phase 2

Ebola Virus Disease

Molnupiravir 200 mg

Phase 2

SARS-CoV-2 Infection, COVID-19

MK-0646

Phase 2

Neuroendocrine Tumors

Ibutamoren Mesylate (MK-0677)

Phase 2

Fibromyalgia

Pembrolizumab, Cetuximab

Phase 2

HNSCC

TILT-123

Phase 2

Platinum-refractory Ovarian Carcinoma

Capecitabine/ 5-FU

Phase 2

Colorectal Cancer

Cetuximab (Erbitux)

Phase 2

Cancer

FOLFOX-4+cetuximab

Phase 2

Colorectal Cancer

quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine or nonavalent human papillomavirus vaccine (HPV 6, 11, 16, 18, 31, 33, 45, 52, 58)

Phase 2

Cancer Survivor

Nesuparib

Phase 2

Endometrial Cancer

Odetiglucan

Phase 2

Colorectal Adenocarcinoma Metastatic in the Liver

rVSVΔG-ZEBOV-GP, V920

Phase 2

Ebola Virus Disease

Ataluren + Pembrolizumab

Phase 2

Colorectal Cancer

Cyclophosphamide 50mg

Phase 2

Metastatic Breast Cancer

Lonafarnib

Phase 2

Breast Cancer

breast cancer

2 drugs in this indication

cancer

2 drugs in this indication

HPV vaccine

1 drug in this indication

muscle invasive bladder cancer

1 drug in this indication

Muscle-invasive bladder cancer (MIBC), neoadjuvant and adjuvant treatment

1 drug in this indication

Non Small Cell Lung Cancer

1 drug in this indication

Melanoma Stage IV

1 drug in this indication

dMMR endometrial cancer

1 drug in this indication

Ebola

1 drug in this indication

oncology

1 drug in this indication

first-line treatment (specific indication not stated)

1 drug in this indication

cholesterol

1 drug in this indication

to reduce LDL-C in adults with hypercholesterolemia

1 drug in this indication

dMMR advanced or recurrent endometrial cancer

1 drug in this indication

cardiovascular disease

1 drug in this indication

Hypercholesterolemia (high levels of bad cholesterol)

1 drug in this indication

resectable muscle-invasive bladder cancer (MIBC)

1 drug in this indication

Hepatitis C, Chronic

1 drug in this indication

Dyslipidemia

1 drug in this indication

cholesterol-lowering

1 drug in this indication

PCSK9 inhibitor for LDL-C and Lp(a) lowering

1 drug in this indication

Hepatitis C

1 drug in this indication

PANCREAS

1 drug in this indication

HIV PrEP

1 drug in this indication

Melanoma

1 drug in this indication

Recurrent Mantle Cell Lymphoma

1 drug in this indication

Small Cell Lung Cancer

1 drug in this indication

kidney cancer

1 drug in this indication

Diabetic Macular Edema (DME)

1 drug in this indication

advanced renal cell carcinoma

1 drug in this indication

diabetic macular edema

1 drug in this indication

eye disease

1 drug in this indication

Non-small Cell Lung Cancer, NSCLC

1 drug in this indication

Source: CatalystAlert database (ClinicalTrials.gov, SEC EDGAR)

📑
Catalyst DossierPRO
The full research note — thesis, the if-approved scenario, financials & smart money. Compiled by CeliA.
→
Catalyst Verdict

Full breakdown — the signals behind the verdict

Market-Implied Move
Regulatory Approvals

Frequently asked questions

What is in MERCK's drug pipeline?→

CatalystAlert tracks 837 drug candidates in MERCK's (MRK) pipeline across Phase 3, Phase 2. Its lead program is ULO (Phase 3). Each drug's phase, indication and upcoming catalysts are listed on this page.

When is MERCK's next FDA catalyst?→

MERCK's (MRK) next tracked catalyst is a Phase 3 expected September 15, 2026. See the catalyst timeline on this page for the full schedule of PDUFA dates, trial readouts and FDA events.

How do I track MRK biotech catalysts?→

Add MRK to your CatalystAlert watchlist for alerts ahead of each catalyst, and follow MERCK's live catalyst calendar, drug pipeline and clinical-trial timeline on this page — sourced from ClinicalTrials.gov, FDA and SEC filings.

Get Catalyst Alerts
Receive weekly digests of upcoming catalysts

Weekly digest every Monday. Unsubscribe anytime.

Data is aggregated from public sources (FDA, SEC, ClinicalTrials.gov). While we strive for accuracy, information may be incomplete, delayed, or contain errors. Terms apply