Novartis AG

PSMA-positive Metastatic Castration Resistant Prostate Cancer (mCRPC) With Prior Exposure to One Prior ARPI Who Are Candidates for Taxane-based Chemotherapy

AIN457A

Phase 2

Ankylosing Spondylitis

INC280

Phase 2

Non-small Cell Lung Cancer

Iptacopan (part 1)

Phase 2

Lupus Nephritis

MF59-eH5N1

Phase 2

Pandemic

UNR844-Cl

Phase 2

Presbyopia

Nilotinib followed by treatment-free

Phase 2

Chronic Myelogenous Leukemia

Entacapone

Phase 2

Parkinson's Disease

Extended Release Methylphenidate (Ritalin LA ) plus Behavior Therapy

Phase 2

Attention Deficit Hyperactivity Disorder

AHU377

Phase 2

Hypertension

[68Ga]Ga-NeoB

Phase 2

Breast Cancer

AFQ056

Phase 2

Parkinson's Disease

AUY922

Phase 2

Non-small-cell Lung Cancer

Patupilone

Phase 2

Metastatic Hormone Refractory Prostate Cancer

Investigational new drug, company code: BGG492

Phase 2

Partial Onset Seizures

Zoledronic Acid; Letrozole

Phase 2

Breast Cancer

TCH346

Phase 2

Amyotrophic Lateral Sclerosis

rapcabtagene autoleucel (YTB323)

Phase 2

Progressive Multiple Sclerosis

Deferasirox granule formulation

Phase 2

Transfusion-dependent Anemia

PTK787/ZK 222584

Phase 2

Von Hippel-Lindau Disease

HSC835

Phase 2

Acute Myelocytic Leukemia

STI571

Phase 2

Systemic Sclerosis, Scleroderma

PDR001

Phase 2

Melanoma

QAX576

Phase 2

Asthma

Indacaterol 300μg

Phase 2

Chronic Obstructive Pulmonary Disease

Drug Name	Phase	Indication	Designations
QAB149	Phase 3	COPD	-
Monovalent A/H1N1 influenza vaccine	Phase 3	Pandemic Influenza	-
Terbinafine hydrochloride (HCl)	Phase 3	Tinea Capitis	-
MenACWY-CRM197 (two doses)	Phase 3	Meningococcal Meningitis	-
Iptacopan (LNP023)	Phase 3	Paroxysmal Nocturnal Hemoglobinuria (PNH)	-
MenACWY-CRM conjugate vaccine	Phase 3	Meningococcal Meningitis	-
Zoledronic acid 4 mg	Phase 3	Non-Small-Cell Lung Cancer	-
Indacaterol 300 μg	Phase 3	Asthma	-
Licarbazepine	Phase 3	Bipolar I Disorder	-
sitagliptin	Phase 3	Diabetes Mellitus, Type 2	-
Aliskiren	Phase 3	Hypertension	-
Pelacarsen (TQJ230)	Phase 3	Atherosclerotic Cardiovascular Disease	-
Secukinumab	Phase 3	Psoriatic Arthritis	-
AIN457	Phase 3	Behcet Disease	-
Everolimus	Phase 3	Kidney Transplantation	-
Fulvestrant	Phase 3	Breast Cancer	-
AAA617	Phase 3	Oligometastatic Prostate Cancer (OMPC)	-
[18F]CTT1057	Phase 3	Prostatic Neoplasms	-
ranibizumab	Phase 3	Choroidal Neovascularization	-
NVA237	Phase 3	Chronic Obstructive Pulmonary Disease	-
Valsartan	Phase 3	Hypertension	-
cyclosporine	Phase 3	de Novo Kidney Transplant Recipients	-
Zoledronic acid	Phase 3	Cancer Prostate	-
Glimepiride	Phase 3	Diabetes Mellitus, Type 2	-
secukinumab 150 mg	Phase 3	Moderate to Severe Plaque-type Psoriasis	-
QVA149	Phase 3	Chronic Obstructive Pulmonary Disease (COPD)	-
Bexsero® vaccine (1 dose at study month zero)	Phase 3	Meningoccocal Disease	-
Meningococcal B Recombinant + Outer Membrane Vesicle vaccine (rMenB+OMV NZ)	Phase 3	N. Meningitidis Carriage	-
secukinumab 300 mg	Phase 3	Moderate to Severe Palmoplantar Psoriasis	-
Paclitaxel	Phase 3	Breast Cancer	-
Focalin XR	Phase 3	ADHD	-
Brolucizumab	Phase 3	Diabetic Macular Edema	-
BYM338/bimagrumab	Phase 3	Sporadic Inclusion Body Myositis	-
Vildagliptin	Phase 3	Diabetes Mellitus, Type 2	-
MF59-eH1N1_f	Phase 3	Influenza	-
Metformin	Phase 3	Diabetes Mellitus, Type 2	-
Ianalumab	Phase 3	Warm Autoimmune Hemolytic Anemia (wAIHA)	-
Brolucizumab 6 mg	Phase 3	Proliferative Diabetic Retinopathy	-
FTY720	Phase 3	Renal Transplantation	-
secukinumab 150mg	Phase 3	Plaque-type Psoriasis	-
Depiquick Birch (DPG103)	Phase 3	Allergic Rhinoconjunctivitis	-
MenACWY CRM	Phase 3	Meningococcal Infections	-
Influenza vaccine	Phase 3	Influenza	-
Indacaterol	Phase 3	Chronic Obstructive Pulmonary Disease	-
agomelatine	Phase 3	Major Depressive Disorder	-
Imatinib	Phase 3	Chronic Myeloid Leukemia	-
Ofatumumab	Phase 3	Relapsing Multiple Sclerosis	-
Deferasirox	Phase 3	Beta-thalassemia	-
canakinumab	Phase 3	NALP3 Mutation	-
Secukinumab (AIN457)	Phase 3	Psoriatic Arthritis	-
Remibrutinib Dose A	Phase 3	Hidradenitis Suppurativa	-
HCQ	Phase 3	Covid-19	-
Tegaserod	Phase 3	Heartburn	-
valsartan 160 mg	Phase 3	Chronic Heart Failure	-
letrozole	Phase 3	Breast Cancer	-
Haemophilus influenzae type b (Hib) vaccine	Phase 3	Haemophilus Influenzae Type b (Hib) Infection	-
Indacaterol 150 µg	Phase 3	Chronic Obstructive Pulmonary Disease	-
Lumiracoxib	Phase 3	Osteoarthritis	-
eH1N1_f	Phase 3	Novel 2009 Influenza H1N1	-
Valsartan/amlodipine 160/5 mg	Phase 3	Essential Hypertension	-
Cell culture derived seasonal trivalent influenza vaccine (cTIV)	Phase 3	Influenza	-
cTIV	Phase 3	Seasonal Influenza Vaccine	-
etanercept	Phase 3	Chronic Plaque Psoriasis	-
TQJ230	Phase 3	Elevated Lp(a) and Established Atherosclerotic Cardiovascular Disease	-
Trivalent split influenza vaccine (TIV)	Phase 3	Influenza Disease	-
preservative free inactivated split influenza vaccine using the strain composition 2006/2007	Phase 3	Influenza	-
LCZ696	Phase 3	Heart Failure	-
Amlodipine 5 mg	Phase 3	Hypertension	-
Valsartan 0.25 mg/kg	Phase 3	Hypertension	-
Meningococcal ACWY conjugate vaccine (MenACWY-CRM)	Phase 3	Meningococcal Disease	-
onasemnogene abeparvovec-xioi	Phase 3	Spinal Muscular Atrophy	-
Rivastigmine Transdermal Patch	Phase 3	Alzheimer's Disease	-
Iptacopan	Phase 3	Glomerulonephritis, IGA	-
Dabrafenib	Phase 3	Melanoma	-
secukinumab low dose	Phase 3	Moderate to Severe Chronic Plaque-type Psoriasis	-
Famciclovir	Phase 3	Genital Herpes	-
Crizanlizumab (SEG101)	Phase 3	Sickle Cell Disease (SCD)	-
Pimecrolimus	Phase 3	Atopic Dermatitis	-
INC424	Phase 3	Myelofibrosis	-
Ranibizumab 0.5mg	Phase 3	Visual Impairment Due to Choroidal Neovascularization (CNV) Secondary to Pathologic Myopia (PM)	-
valsartan + amlodipine	Phase 3	Hypertension	-
Rivastigmine	Phase 3	Vascular Dementia	-
Amlodipine	Phase 3	Essential Hypertension	-
Monovalent inactivated influenza vaccine	Phase 3	Pre-pandemic Influenza Vaccine	-
Ribociclib	Phase 3	Early Breast Cancer	-
Indacaterol 150 μg	Phase 3	Chronic Obstructive Pulmonary Disease (COPD)	-
Ranibizumab 0.5 mg	Phase 3	Macular Edema Secondary to Branch Retinal Vein Occlusion	-
Ligelizumab	Phase 3	Chronic Spontaneous Urticaria	-
Nilotinib	Phase 3	Gastrointestinal Stromal Tumors	-
Inclisiran	Phase 3	Familial Hypercholesterolemia - Homozygous	-
oxcarbazepine	Phase 3	Epilepsy	-
Omalizumab	Phase 3	Asthma	-
valsartan/amlodipine	Phase 3	Hypertension	-
Ofatumumab subcutaneous injection	Phase 3	Relapsing Multiple Sclerosis	-
Enteric-coated mycophenolate sodium (EC-MPS)	Phase 3	Renal Transplantation	-
DTwP-HepB-Hib Vaccine	Phase 3	Diphtheria	-
LNP023	Phase 3	IgA Nephropathy	-
Ali/Amlo 150/2.5 mg	Phase 3	Essential Hypertension	-
Trivalent influenza virus vaccine (TIV)	Phase 3	Pandemic Influenza Disease	-
Ruxolitinib	Phase 3	Primary Myelofibrosis (MF)	-
Tiotropium	Phase 3	Chronic Obstructive Pulmonary Disease	-
Lapatinib	Phase 3	Neoplasms, Breast	-
Fumaric acid	Phase 3	Psoriasis	-
Hydrochlorothiazide (HCTZ)	Phase 3	Hypertension	-
Ustekinumab	Phase 3	Plaque Psoriasis	-
MenACWY-CRM	Phase 3	Meningococcal Infections	-
diclofenac diethylamine gel 2.32%	Phase 3	Grade I/II Ankle Sprain	-
QAW039	Phase 3	Asthma	-
Cell culture-derived influenza subunit vaccine (cTIV)	Phase 3	Influenza	-
Secukinumab 300 mg, s.c.	Phase 3	Giant Cell Arteritis	-
Entecavir	Phase 3	Hepatitis B	-
Certoparin	Phase 3	Persistent Nonvalvular Atrial Fibrillation	-
Salmeterol 50 μg	Phase 3	Chronic Obstructive Pulmonary Disease (COPD)	-
Olmesartan	Phase 3	Essential Hypertension	-
Fingolimod	Phase 3	Chronic Inflammatory Demyelinating Polyradiculoneuropathy	-
vinorelbine	Phase 3	HER2/Neu Over-expressing Locally Advanced Breast Cancer	-
Hydrochlorothiazide	Phase 3	Hypertension	-
hATG	Phase 2	Aplastic Anemia	-
LTP	Phase 2	Healthy Volunteers, Pulmonary Arterial Hypertension	-
Aliskiren 3.125 mini-tablets	Phase 2	Hypertension	-
75 µg indacaterol maleate (LB)	Phase 2	Asthma	-
asciminib	Phase 2	Leukemia, Chronic Myelogenous	-
Relaxin	Phase 2	Heart Failure, Congestive	-
MCS110	Phase 2	Pigmented Villonodular Synovitis	-
tisagenlecleucel	Phase 2	Follicular Lymphoma	-
EYU688	Phase 2	Dengue	-
Calcium carbonate/magnesium hydroxide/Lansoprazole 15 mg	Phase 2	Heartburn	-
LIK066	Phase 2	Elevated Body Mass Index	-
LEZ763	Phase 2	Type II Diabetes	-
SBR759	Phase 2	Hyperphosphatemia Patients With Chronic Kidney Disease on 3x/Week Replacement Therapy	-
Indacaterol maleate 400 μg	Phase 2	Asthma	-
Ceritinib	Phase 2	ALK-positive Non-small Cell Lung Cancer	-
Surface Antigen, Inactivated, (Adjuvanted with MF59C.1), form. 2006-07	Phase 2	Influenza	-
CTL019	Phase 2	B-cell Acute Lymphoblastic Leukemia	-
TKI258	Phase 2	Solid Tumors and Advanced Endometrial Cancer	-
Deferasirox dispersible tablet	Phase 2	Chronic Iron Overload Due to Transfusion-dependant Anemias	-
Daunorubicin	Phase 2	Acute Leukaemia	-
Secukinumab 10 mg/kg	Phase 2	Dry Eye	-
QVM149 150/50/80 μg o.d.	Phase 2	Asthma	-
BEZ235 (Stage 1)	Phase 2	Pancreatic Neuroendocrine Tumors (pNET)	-
EGF816	Phase 2	Advanced Non-small Cell Lung Cancer	-
VAY736 1ml PFS	Phase 2	Sjögrens Disease	-
cyclosporine (reduced exposure) / everolimus	Phase 2	Kidney Transplantation	-
AEE788	Phase 2	Brain and Central Nervous System Tumors	-
imatinib mesylate	Phase 2	Leukemia	-
MenACWY-CRM197	Phase 2	Meningococcal Disease	-
GIA632	Phase 2	Atopic Dermatitis	-
Rapcabtagene autoleucel	Phase 2	Idiopathic Inflammatory Myopathies	-
Seasonal Influenza Vaccine	Phase 2	Influenza	-
Meningococcal Vaccine	Phase 2	Meningococcal Disease	-
Indacaterol (QAB149)	Phase 2	COPD	-
MenABCWY+OMV	Phase 2	Meningococcal Disease	-
Trametinib	Phase 2	Cancer	-
AFQ056 with L-dopa	Phase 2	Parkinson's Disease	-
RLX030	Phase 2	Chronic Heart Failure (CHF)	-
Sildenafil	Phase 2	Mild to Moderate Hypertension	-
NGI226	Phase 2	Achilles Tendinopathy	-
CJM112	Phase 2	Hidradenitis Suppurativa (Acne Inversa)	-
balicatib (AAE581)	Phase 2	Knee Osteoarthritis	-
ICL670, deferoxamine	Phase 2	Anemia, Sickle Cell	-
AEB071	Phase 2	Uveitis	-
Group B Streptococcus Trivalent Vaccine	Phase 2	Streptococcal Infection	-
eltrombopag	Phase 2	Thrombocytopaenia	-
serogroup B meningococcal vaccine	Phase 2	Meningococcal Disease	-
IGE025	Phase 2	Chronic Idiopathic Urticaria	-
AMO959	Phase 2	PSMA-positive Metastatic Castration Resistant Prostate Cancer (mCRPC) With Prior Exposure to One Prior ARPI Who Are Candidates for Taxane-based Chemotherapy	-
AIN457A	Phase 2	Ankylosing Spondylitis	-
INC280	Phase 2	Non-small Cell Lung Cancer	-
Iptacopan (part 1)	Phase 2	Lupus Nephritis	-
MF59-eH5N1	Phase 2	Pandemic	-
UNR844-Cl	Phase 2	Presbyopia	-
Nilotinib followed by treatment-free	Phase 2	Chronic Myelogenous Leukemia	-
Entacapone	Phase 2	Parkinson's Disease	-
Extended Release Methylphenidate (Ritalin LA ) plus Behavior Therapy	Phase 2	Attention Deficit Hyperactivity Disorder	-
AHU377	Phase 2	Hypertension	-
[68Ga]Ga-NeoB	Phase 2	Breast Cancer	-
AFQ056	Phase 2	Parkinson's Disease	-
AUY922	Phase 2	Non-small-cell Lung Cancer	-
Patupilone	Phase 2	Metastatic Hormone Refractory Prostate Cancer	-
Investigational new drug, company code: BGG492	Phase 2	Partial Onset Seizures	-
Zoledronic Acid; Letrozole	Phase 2	Breast Cancer	-
TCH346	Phase 2	Amyotrophic Lateral Sclerosis	-
rapcabtagene autoleucel (YTB323)	Phase 2	Progressive Multiple Sclerosis	-
Deferasirox granule formulation	Phase 2	Transfusion-dependent Anemia	-
PTK787/ZK 222584	Phase 2	Von Hippel-Lindau Disease	-
HSC835	Phase 2	Acute Myelocytic Leukemia	-
STI571	Phase 2	Systemic Sclerosis, Scleroderma	-
PDR001	Phase 2	Melanoma	-
QAX576	Phase 2	Asthma	-
Indacaterol 300μg	Phase 2	Chronic Obstructive Pulmonary Disease	-

Regulatory & News

Approvals, filings, and latest developments

Regulatory Approvals

NVS News