What is CatalystAlert?

CatalystAlert is a biotech catalyst tracking platform with AI-powered predictions that helps investors monitor PDUFA dates, clinical trial results, FDA decisions, and predict stock price movements for over 1,000 biotechnology companies.

How much does CatalystAlert cost?

CatalystAlert offers a free tier with access to the catalyst calendar, company profiles, and basic features. Premium tiers (Starter $9.99/mo, Pro $19.99/mo, Elite $39.99/mo) unlock advanced ML predictions, entry timing signals, and priority alerts.

Where does CatalystAlert get its data?

CatalystAlert aggregates data from official sources including ClinicalTrials.gov, SEC EDGAR filings, FDA openFDA database, EMA, and company press releases. Our ML models are trained on 880+ historical catalyst events with complete price data.

What types of biotech catalysts are tracked?

We track PDUFA dates, Phase 1/2/3 clinical trial results, FDA Advisory Committee meetings (AdCom), NDA/BLA filings, earnings reports, conference presentations, EMA approvals, and other regulatory events worldwide.

How does CatalystAlert predict stock price movements?

Our XGBoost machine learning model (82.7% accuracy, 0.89 AUC-ROC) analyzes catalyst characteristics, therapeutic area, clinical phase, FDA designations, historical patterns, and market conditions to predict potential stock price impacts.

What is Likelihood of Approval (LOA)?

LOA is a probability score predicting the chance of FDA approval for a drug based on its phase, therapeutic area, trial design, and special designations like Breakthrough Therapy or Fast Track. Our Random Forest model is calibrated against BIO 2024 industry benchmarks.

How often is the data updated?

Core data syncs every 2-6 hours from official government databases. ML models are retrained weekly with new outcomes. Real-time alerts notify subscribers within minutes of major announcements.

Can I get alerts for specific catalysts?

Yes! Create a watchlist of companies you follow and enable push notifications to receive instant alerts when catalysts approach, results are announced, or significant price movements occur.

AI-Powered Biotech Intelligence

Never Miss a Biotech Catalyst

Track PDUFA dates, Phase 3 results, and FDA decisions for 1,315+ biotech stocks. ML predictions with 82.7% accuracy help you time your entries.

View Catalyst Calendar Best Entry Timing

Data updated 4m ago

1,315

Biotech Companies

9,183

Drug Pipelines

2,477

Upcoming Catalysts

82.7%

ML Accuracy

Upcoming Catalysts

The next big biotech events

View All

Jan 20, 2026

AZN.LPhase 2

AZD4117 Phase 2 Results Expected

AstraZeneca PLC

Jan 27, 2026

NVSPhase 2

NGI226 Phase 2 Results Expected

Novartis AG

Jan 27, 2026

ROCHE⭐Phase 3

Teriflunomide Phase 3 Results Expected

Roche Holding AG

Jan 27, 2026

ROCHE⭐Phase 3

Fenebrutinib Phase 3 Results Expected

Roche Holding AG

Jan 28, 2026

REGNPhase 2

REGN7544 Phase 2 Results Expected

Regeneron Pharmaceuticals, Inc.

Recent Results

Latest FDA decisions and trial outcomes

View All

VNDAapproved

FDA PDUFA Date Hetlioz (standard)

Vanda Pharmaceuticals Inc.

SAN.PAapproved

FDA PDUFA Date Tirzepatide (standard)

Sanofi

SAN.PAapproved

FDA PDUFA Date Sutimlimab (priority)

Sanofi

PHARapproved

FDA PDUFA Date leniolisib (priority)

Pharming Group N.V.

OMERapproved

FDA PDUFA Date OMIDRIA (standard)

Omeros Corporation

IPO Calendar

Upcoming Biotech IPOs

Track initial public offerings from biotechnology and pharmaceutical companies

Next Biotech IPOs

Upcoming initial public offerings

View Full IPO Calendar

Biotech IPOs

Total Deal Value

Why Track IPOs?

Biotech IPOs offer early access to innovative companies developing breakthrough therapies. Stay informed about new investment opportunities.

Explore IPOs

AI-Powered Analytics

Make Smarter Investment Decisions

Our machine learning models analyze thousands of clinical trials and FDA decisions to predict outcomes and help you understand the biotech landscape.

XGBoost Model

Stock Impact Prediction

Predict potential stock price movement based on upcoming catalysts

Directional prediction (up/down/neutral)
Confidence score with key factors
Trained on 880+ catalyst patterns

Random Forest

Trial Success Probability

Estimate likelihood of approval based on trial characteristics

Phase-specific success rates
Therapeutic area benchmarks
Designation impact analysis

BIO 2024 Data

Industry Benchmarks

Compare against industry-wide success rates and averages

Phase transition success rates
Therapeutic area LOA data
Historical trend analysis

Clinical Phase Success Rates

Industry averages for phase transitions (BIO 2024)

Phase 1 → 263.2%

Phase 2 → 330.7%

Phase 3 → NDA58.1%

NDA → Approval85.3%

Source: BIO Industry Analysis 2024

Likelihood of Approval by Area

Overall LOA from Phase 1 to approval by therapeutic area

26.1%

Hematology

19.1%

Infectious Disease

7.9%

Oncology

8.2%

Neurology

9.4%

Cardiovascular

15.3%

Autoimmune

Higher rates indicate historically better approval odds

How Our ML Works

Data-Driven Predictions You Can Trust

1. Data Collection: We collect historical data from ClinicalTrials.gov, FDA decisions, and market data.

2. Feature Engineering: Our models analyze phase, therapeutic area, designations, market cap, and more.

3. Model Training: XGBoost for impact prediction, Random Forest for LOA - calibrated for accurate probabilities.

4. Continuous Learning: Models retrain weekly with new outcomes to improve accuracy.

Explore Analytics

Predictions are for informational purposes only and NOT financial advice. Past performance does not guarantee future results. Always conduct your own research and consult a financial advisor before making investment decisions.

Everything You Need

Professional biotech intelligence for serious investors

Catalyst Calendar

Interactive calendar with all upcoming FDA dates and trial readouts

ML Predictions

AI-powered stock impact and entry timing predictions (82.7% accuracy)

Entry Timing

Optimal entry points calculated from historical catalyst patterns

Real-time Alerts

Push notifications for catalyst results and watchlist updates

Why CatalystAlert?

Real-time Updates

Data synced daily from ClinicalTrials.gov, SEC filings, and FDA announcements

Official Sources

All data comes directly from government databases and official company filings

Tiered Access

Free tier for browsing, premium tiers unlock ML predictions and alerts

Data Sources

ClinicalTrials.gov - Clinical trial phases and timelines
SEC EDGAR - 8-K filings and press releases
FDA openFDA - Drug approvals and PDUFA dates

Get Catalyst Alerts

Receive weekly digests of upcoming catalysts

Start Trading Smarter

Join thousands of biotech traders using AI-powered predictions to time their entries. Free tier available, upgrade anytime for ML predictions and alerts.

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